Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sharbani, Phukan"'
Autor:
Boris Pasche, Albert de la Chapelle, Antonio Di Cristofano, Laura Valle, Chiang-Ching Huang, Guang-Yu Yang, Jie Liao, Michael Pennison, Diana S. Rosman, Maureen Sadim, Yanfei Xu, Sharbani Phukan, Qinghua Zeng
Supplementary Figure 1 from Tgfbr1 Haploinsufficiency Is a Potent Modifier of Colorectal Cancer Development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f4a33d39d4ae12c565bf358646241d
https://doi.org/10.1158/0008-5472.22377507.v1
https://doi.org/10.1158/0008-5472.22377507.v1
Autor:
Paul J. Grippo, Boris Pasche, David J. Bentrem, Maureen Sadim, Sharbani Phukan, Yanfei Xu, Akilesh Honasoge, Eric C. Cheon, Morgan R. Barron, Qinghua Zeng, Matthew J. Strouch, Kevin Adrian
Supplementary Table 2 from Tgfbr1 Haploinsufficiency Inhibits the Development of Murine Mutant Kras-Induced Pancreatic Precancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8668d731d9ce784b2c4d58c6dfb3fa
https://doi.org/10.1158/0008-5472.22381893
https://doi.org/10.1158/0008-5472.22381893
Autor:
Paul J. Grippo, Boris Pasche, David J. Bentrem, Maureen Sadim, Sharbani Phukan, Yanfei Xu, Akilesh Honasoge, Eric C. Cheon, Morgan R. Barron, Qinghua Zeng, Matthew J. Strouch, Kevin Adrian
Supplementary Table 1 from Tgfbr1 Haploinsufficiency Inhibits the Development of Murine Mutant Kras-Induced Pancreatic Precancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a418bd6a5820c31be5bc5e06a6887953
https://doi.org/10.1158/0008-5472.22381896.v1
https://doi.org/10.1158/0008-5472.22381896.v1
Autor:
Paul J. Grippo, Boris Pasche, David J. Bentrem, Maureen Sadim, Sharbani Phukan, Yanfei Xu, Akilesh Honasoge, Eric C. Cheon, Morgan R. Barron, Qinghua Zeng, Matthew J. Strouch, Kevin Adrian
To dissect the role of constitutively altered Tgfbr1 signaling in pancreatic cancer development, we crossed Elastase-KrasG12D (EL-Kras) mice with Tgfbr1 haploinsufficient mice to generate EL-Kras/Tgfbr1+/− mice. Mice were euthanized at 6 to 9 month
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12aa2bcf36af0b511540d79e3ab328d5
https://doi.org/10.1158/0008-5472.c.6500016.v1
https://doi.org/10.1158/0008-5472.c.6500016.v1
Autor:
Paul J. Grippo, Boris Pasche, David J. Bentrem, Maureen Sadim, Sharbani Phukan, Yanfei Xu, Akilesh Honasoge, Eric C. Cheon, Morgan R. Barron, Qinghua Zeng, Matthew J. Strouch, Kevin Adrian
Supplementary Table Legends 1-2 from Tgfbr1 Haploinsufficiency Inhibits the Development of Murine Mutant Kras-Induced Pancreatic Precancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a359843e9e0392e04c9d5cfc03c650be
https://doi.org/10.1158/0008-5472.22381890
https://doi.org/10.1158/0008-5472.22381890
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 23:988-993
Objective— Early growth response gene (Egr)-1 is a key transcription factor involved in vascular pathophysiology. Its role in diabetic vascular complications, however, remains unclear. Because hyperinsulinemia and hyperglycemia are major risk facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8cc2770b727e3a13b69c3aa2544a2f
https://doi.org/10.1161/01.atv.0000071351.07784.19
https://doi.org/10.1161/01.atv.0000071351.07784.19
Autor:
Matthew J. Strouch, Akilesh Honasoge, Paul J. Grippo, Eric C. Cheon, Sharbani Phukan, Qinghua Zeng, Yanfei Xu, Maureen Sadim, David J. Bentrem, Boris Pasche, Kevin Adrian, Morgan R. Barron
Publikováno v:
Cancer research. 69(24)
To dissect the role of constitutively altered Tgfbr1 signaling in pancreatic cancer development, we crossed Elastase-KrasG12D (EL-Kras) mice with Tgfbr1 haploinsufficient mice to generate EL-Kras/Tgfbr1+/− mice. Mice were euthanized at 6 to 9 month
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d108d548baccdbc2d91d64f8440cd7e6
https://pubmed.ncbi.nlm.nih.gov/19951995
https://pubmed.ncbi.nlm.nih.gov/19951995
TGFBR1*6A is a common hypomorphic variant of the type 1 transforming growth factor β receptor (TGFBR1), which has been associated with increased cancer risk in some studies. Although TGFBR1*6A is capable of switching TGF-β growth-inhibitory signals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a0b4960e261ea0ebbbbefd3ebc7a84d
https://europepmc.org/articles/PMC2673101/
https://europepmc.org/articles/PMC2673101/
Autor:
Kenneth Offit, Yu Chen, Carole Oddoux, Lisa Baddi, Helen Huang, Diana S. Rosman, Loren S. Michel, Sharbani Phukan, Virginia G. Kaklamani, Habibul Ahsan, Junjian Liu, Ciarán Bradley, Boris Pasche, Alfred Rademaker, Harry Ostrer, Bree McDaniel, Chris Hegarty
Publikováno v:
Cancer research. 65(8)
There is growing evidence that common variants of the transforming growth factor-β (TGF-β) signaling pathway may modify breast cancer risk. In vitro studies have shown that some variants increase TGF-β signaling, whereas others have an opposite ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc8cc27e6d4e5eb9d78335a5e489f53e
https://pubmed.ncbi.nlm.nih.gov/15833881
https://pubmed.ncbi.nlm.nih.gov/15833881
Autor:
Boris, Pasche, Thomas J, Knobloch, Yansong, Bian, Junjian, Liu, Sharbani, Phukan, Diana, Rosman, Virginia, Kaklamani, Lisa, Baddi, Farida S, Siddiqui, Wendy, Frankel, Thomas W, Prior, David E, Schuller, Amit, Agrawal, Jas, Lang, M Eileen, Dolan, Everett E, Vokes, William S, Lane, Chiang-Ching, Huang, Trinidad, Caldes, Antonio, Di Cristofano, Heather, Hampel, IngMarie, Nilsson, Gunnar, von Heijne, Riccardo, Fodde, V V V S, Murty, Albert, de la Chapelle, Christopher M, Weghorst
Publikováno v:
JAMA-Journal of the American Medical Association, 294(13), 1634-1646. American Medical Association
TGFBR1*6A is a common polymorphism of the type I transforming growth factor beta receptor (TGFBR1). Epidemiological studies suggest that TGFBR1*6A may act as a tumor susceptibility allele. How TGFBR1*6A contributes to cancer development is largely un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8050103421981c59190d8b5ea63a6f43
https://pure.eur.nl/en/publications/441618dc-7ac6-4829-a9ef-a2673d80813c
https://pure.eur.nl/en/publications/441618dc-7ac6-4829-a9ef-a2673d80813c