Peficitinib halts acute kidney injury via JAK/STAT3 and growth factors immunomodulation.

Autor: Ibrahim H; Pharmacology and Toxicology Department, Faculty of Pharmacy, Mansoura University, Mansoura, 33516, Egypt; Pharmacist at Urology and Nephrology Center, Mansoura University, Mansoura, 33516, Egypt., Sharawy MH; Pharmacology and Toxicology Department, Faculty of Pharmacy, Mansoura University, Mansoura, 33516, Egypt. Electronic address: maha_sharawy@hotmail.com., Hamed MF; Pathology Department, Faculty of Veterinary Medicine, Mansoura University, Mansoura, 33516, Egypt., Abu-Elsaad N; Pharmacology and Toxicology Department, Faculty of Pharmacy, Mansoura University, Mansoura, 33516, Egypt.

Publikováno v: European journal of pharmacology [Eur J Pharmacol] 2024 Sep 28; Vol. 984, pp. 177020. Date of Electronic Publication: 2024 Sep 28.

Roflumilast extenuates inflammation and oxidative stress in cadmium-induced hepatic and testicular injury in rats.

Autor: Sulayman Aboulqassim NS; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt; Department of Pharmacology &Toxicology Faculty of Pharmacy, Derna university, Derna, Libya. Electronic address: naima.alsad@gmail.com., Hazem SH; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt. Electronic address: sarahesham12@mans.edu.eg., Sharawy MH; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt. Electronic address: maha_hesham@mans.edu.eg., Suddek GM; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt. Electronic address: ghmsuddek@mans.edu.eg.

Publikováno v: International immunopharmacology [Int Immunopharmacol] 2023 Nov; Vol. 124 (Pt B), pp. 111027. Date of Electronic Publication: 2023 Oct 12.

Nifuroxazide mitigates doxorubicin-induced cardiovascular injury: Insight into oxidative/NLRP3/GSDMD-mediated pyroptotic signaling modulation.

Autor: Amin FM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt., Sharawy MH; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt., Amin MN; Biochemistry Department, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt; Biochemistry Department, Faculty of Pharmacy, King Salman International University, Ras-Sedr, South Sinai Governorate, Egypt., El-Sherbiny M; Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, P.O. Box 71666, Riyadh 11597, Saudi Arabia; Department of Anatomy, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt., Said E; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt; Department of Pharmacology and Toxicology, Faculty of Pharmacy, New Mansoura University, New Mansoura, 7723730, Egypt. Electronic address: eman.sa3eed@nmu.edu.eg., Salem HA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt., Ibrahim TM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.

Publikováno v: Life sciences [Life Sci] 2023 Feb 01; Vol. 314, pp. 121311. Date of Electronic Publication: 2022 Dec 19.

Canagliflozin interrupts mTOR-mediated inflammatory signaling and attenuates DMBA-induced mammary cell carcinoma in rats.

Autor: Sabaa M; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt., Sharawy MH; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt., El-Sherbiny M; Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, P.O. Box 71666, Riyadh 11597, Saudi Arabia; Department of Anatomy, Faculty of Medicine, Mansoura University, Mansoura, Egypt. Electronic address: msharbini@mcst.edu.sa., Said E; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt; Department of Pharmacology and Toxicology, Faculty of Pharmacy, New Mansoura University, 7723730 New Mansoura, Egypt. Electronic address: emansaid@mans.edu.eg., Salem HA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt., Ibrahim TM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Nov; Vol. 155, pp. 113675. Date of Electronic Publication: 2022 Sep 15.

Anti-fibrotic activity of sitagliptin against concanavalin A-induced hepatic fibrosis. Role of Nrf2 activation/NF-κB inhibition.

Autor: Sharawy MH; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt. Electronic address: maha_sharawy@hotmail.com., El-Kashef DH; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt., Shaaban AA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt; Department of Pharmacology and Biochemistry, Faculty of Pharmacy, Delta University for Science and Technology, Gamasa 11152, Egypt., El-Agamy DS; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt; Department of Pharmacology and Toxicology, College of Pharmacy, Taibah University, Al-Madinah Al-Munawwarah, Saudi Arabia.

Publikováno v: International immunopharmacology [Int Immunopharmacol] 2021 Nov; Vol. 100, pp. 108088. Date of Electronic Publication: 2021 Aug 25.