Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Sharath Balakrishna"'
Autor:
Jagadisha Tavarekere Venkataravanappa, Prasad Kothegala Chandrashekaraiah, Sharath Balakrishna
Publikováno v:
Journal of Krishna Institute of Medical Sciences University, Vol 13, Iss 2, Pp 20-30 (2024)
Background: Chronic Suppurative Otitis Media (CSOM) is an uncontrolled inflammation in the middle ear due to bacterial infections and has been linked to the overactivation of the Toll-Like Receptor 4 (TLR4) pathway. The pathway is activated by Lipopo
Externí odkaz:
https://doaj.org/article/c2d8d524ae5a4164afc050bd10350c74
Publikováno v:
Indian Journal of Dermatology, Vol 67, Iss 2, Pp 133-137 (2022)
Background: Vitiligo is an autoimmune disorder involving inflammatory damage to melanocytes. STAT3 genetic variant (rs744166 T > C) increases inflammatory signaling via JAK/STAT pathway. Aim: The purpose of this study was to check whether this transl
Externí odkaz:
https://doaj.org/article/18e2a4c25dc240c095936f308344b88f
Publikováno v:
Journal of Krishna Institute of Medical Sciences University, Vol 10, Iss 4, Pp 13-20 (2021)
Background: Diabetic Retinopathy (DR), a microvascular complication of Type 2 Diabetes Mellitus (T2DM) is due to retinal neovascularization mediated by Vascular Endothelial Growth Factor (VEGF). Neovascularization involves proteolytic degradation of
Externí odkaz:
https://doaj.org/article/a4aedb7a9a3249e2a7dfb78f05efc271
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 16, Iss 9, Pp BC01-BC04 (2022)
Introduction: Non Alcoholic Fatty Liver Disease (NAFLD) is one of the common liver disease characterised by fat accumulation in hepatocytes. NAFLD is a broad spectrum of simple steatosis, Non Alcoholic Steatohepatisis (NASH), cirrhosis and hepatocell
Externí odkaz:
https://doaj.org/article/16f571da26094056b24583d0ffe9869b
Publikováno v:
Archives of Medicine and Health Sciences, Vol 9, Iss 2, Pp 225-228 (2021)
Background and Aim: Phosphoglucomutase 1 (PGM1) is an enzyme that catalyzes the key step that links glycogen synthesis with glucose metabolism. Single nucleotide polymorphism (SNP) (rs11208257) is a functional variant in the PGM1 gene that codes for
Externí odkaz:
https://doaj.org/article/be1746c7dc084c8d95ed32c4182ded5a
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 16, Iss 1, Pp OC01-OC04 (2022)
Introduction: Excessive signalling via the Receptor for Advanced Glycation End products (RAGE) is implicated in inflammatory renal damage in Diabetic Nephropathy (DN). RAGE signaling is modulated by its soluble form (sRAGE) that arises due to ectodom
Externí odkaz:
https://doaj.org/article/ec22c4e4653a425e8d74bc117c89d2a9
Autor:
Chandrakala Nagarajappa, Sheela Shikaripur Rangappa, Ravishankar Suryanarayana, Sharath Balakrishna
Publikováno v:
Hypertension in Pregnancy, Vol 38, Iss 2, Pp 124-128 (2019)
Objective: To evaluate the association of protein carbonylation with preeclampsia and its correlation with urinary protein misfolding.Method: Protein carbonyl and misfolded protein levels were measured in the midstream urine sample (58 preeclamptic a
Externí odkaz:
https://doaj.org/article/9d4aa2b64e76481cb6fef3e8369658fb
Publikováno v:
Indian Journal of Dermatology, Vol 64, Iss 3, Pp 182-186 (2019)
Background: Genetic variations associated with nonprogression of HIV infection to AIDS are enriched in psoriasis patients. HCP5 gene 335 T > G and chemokine C receptor type 5 (CCR5) gene Δ32 polymorphisms are associated with HIV nonprogression pheno
Externí odkaz:
https://doaj.org/article/fd733ce7625541318e5e2f9d99cf1316
Publikováno v:
Archives of Medicine and Health Sciences, Vol 7, Iss 2, Pp 177-180 (2019)
Background: Alpha-1 antitrypsin (A1AT) is a protease inhibitor that plays an important role in regulating oxidative stress in preeclampsia (PE). Recent studies have shown that A1AT is misfolded in PE. However, the cause of A1AT misfolding is not know
Externí odkaz:
https://doaj.org/article/43e5ea468bcc4324a2140e2e37407151
Autor:
Krishnaveni Changalvala, Pushpa Kotur, Mitesh Shetty, KS Praveen Kumar, TV Jagadish, Sharath Balakrishna, KV Venkateshu
Publikováno v:
Journal of Clinical and Diagnostic Research, Vol 14, Iss 2, Pp GC09-GC13 (2020)
Introduction: Pre-Eclampsia (PE) is a pregnancy-specific disorder which further complicates and leads to eclampsia. The Factor V Leiden (FVL) is an autosomal dominant genetic abnormality with incomplete penetrance predisposes to thrombosis. It codes
Externí odkaz:
https://doaj.org/article/eb2ecba762094e87ba14a75a8fa8a2cb