Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sharareh Movafagh"'
Autor:
Katja Kaipio-Salmi, Ulriikka Jaakkola, Rosemary D. Higgins, Jaana Kallio, Markku Koulu, Zofia Zukowska, Sharareh Movafagh, Helena Seppälä, Yixun Geng, Matti K. Karvonen, Ullamari Pesonen, E. Vainio-Jylhä, Jukka Tuohimaa, Matti Pöllönen, Edward Lee
Publikováno v:
Annals of Medicine. 36:232-240
Neuropeptide Y is a sympathetic neurotransmitter, a potent endothelium-derived angiogenic factor and a vascular mitogen. We have studied the role of the functional leucine7 to proline7 polymorphism of the signal peptide region of preproneuropeptide Y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2976861a8d81efc29e4792d9995a12a
https://doi.org/10.1080/07853890410031236
https://doi.org/10.1080/07853890410031236
Autor:
Sarah Spiegel, James R. Van Brocklyn, Fang Wang, Sharareh Movafagh, Sheldon Milstien, John P. Hobson, Zofia Zukowska-Grojec
Publikováno v:
Journal of Biological Chemistry. 274:35343-35350
Sphingosine 1-phosphate (SPP) has been shown to inhibit chemotaxis of a variety of cells, in some cases through intracellular actions, while in others through receptor-mediated effects. Surprisingly, we found that low concentrations of SPP (10-100 nM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::924da9ed73cfa44c5aebb5aae00e5e91
https://doi.org/10.1074/jbc.274.50.35343
https://doi.org/10.1074/jbc.274.50.35343
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 20(11)
Previously we discovered that NPY induces ischemic angiogenesis by activating Y2 and Y5 receptors. The receptors that mediate specific steps of the complex process of angiogenesis are unknown. Here, we studied in vitro NPY receptors subtypes involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e495666103f09bb88a1d2e344082757c
https://pubmed.ncbi.nlm.nih.gov/16891622
https://pubmed.ncbi.nlm.nih.gov/16891622
Publikováno v:
Peptides. 24(1)
Which of Y1-Y5 receptors (Rs) mediate NPY's angiogenic activity was studied using Y2R-null mice and R-specific antagonists. In Y2R-null mice, NPY-induced aortic sprouting and in vivo Matrigel capillary formation were decreased by 50%; Y1R-antagonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788c528af04d764b07f3c7120dd29a90
https://pubmed.ncbi.nlm.nih.gov/12576090
https://pubmed.ncbi.nlm.nih.gov/12576090
Publikováno v:
Peptides. 23(1)
Age-related changes in NPY-driven angiogenesis were investigated using Matrigel and aortic sprouting assays in young (2 months.) and aged (18 months.) mice. In both assays, NPY-induced vessel growth decreased significantly with age. In parallel, aged
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a84e6b31d94639e08f0cc76b87b72aa
https://pubmed.ncbi.nlm.nih.gov/11814620
https://pubmed.ncbi.nlm.nih.gov/11814620
Autor:
Janice Rone, Hong Ji, Ewa Karwatowska-Prokopczuk, Derrick S. Grant, Hynda K. Kleinman, Zofia Zukowska-Grojec, Wesley Rose, Eric Grouzmann, Wen-Tien Chen, Yunyun Yeh, Sharareh Movafagh
Publikováno v:
Circulation research. 83(2)
Abstract —Sympathetic nerves have long been suspected of trophic activity, but the nature of their angiogenic factor has not been determined. Neuropeptide Y (NPY), a sympathetic cotransmitter, is the most abundant peptide in the heart and the brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb12030a416ac0773502cdd81c5a6d4
https://pubmed.ncbi.nlm.nih.gov/9686758
https://pubmed.ncbi.nlm.nih.gov/9686758