Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Sharareh Emadi"'
Autor:
Wei Xin, Sharareh Emadi, Stephanie Williams, Qiang Liu, Philip Schulz, Ping He, Now Bahar Alam, Jie Wu, Michael R. Sierks
Publikováno v:
Biomolecules, Vol 5, Iss 3, Pp 1634-1651 (2015)
Misfolding and aggregation of α-synuclein into toxic soluble oligomeric α-synuclein aggregates has been strongly correlated with the pathogenesis of Parkinson’s disease (PD). Here, we show that two different morphologically distinct oligomeric α
Externí odkaz:
https://doaj.org/article/fdb65b4277c44de983a273a6e59110e9
Publikováno v:
Neurobiology of Disease, Vol 20, Iss 1, Pp 74-81 (2005)
A key event in Alzheimer's disease (AD) pathogenesis is the conversion of the peptide beta-amyloid (Aβ) from its soluble monomeric form into various aggregated morphologies in the brain. Preventing aggregation of Aβ is being actively pursued as a p
Externí odkaz:
https://doaj.org/article/0d5408e3da704e9aa72ea492ae4b3504
Publikováno v:
International Journal of Cell Biology, Vol 2013 (2013)
In Alzheimer’s disease (AD), tau aggregates into fibrils and higher order neurofibrillary tangles, a key histopathological feature of AD. However, soluble oligomeric tau species may play a more critical role in AD progression since these tau specie
Externí odkaz:
https://doaj.org/article/d688659d761a4c66bdd046b811805a97
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55886 (2013)
Cigarette smoking is associated with a decreased incidence of Parkinson disease (PD) through unknown mechanisms. Interestingly, a decrease in the numbers of α4β2 nicotinic acetylcholine receptors (α4β2-nAChRs) in PD patients suggests an α4β2-nA
Externí odkaz:
https://doaj.org/article/72db4bd4e95c483dbefe6f2b4c44b66b
Autor:
Sharareh Emadi, Bin Feng, Ling Chi, Tiantian Guo, Dhruv Shah, Shivam P Patel, Pablo R. Brumovsky, David M. Pierce, Martin Han
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Colorectal hypersensitivity and sensitization of both mechanosensitive and mechanically insensitive afferents develop after intracolonic instillation of 2,4,6-trinitrobenzenesulfonic acid (TNBS) in the mouse, a model of postinfectious irritable bowel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91e8e957c1e975d117ae95d213fa2d6
https://europepmc.org/articles/PMC8238166/
https://europepmc.org/articles/PMC8238166/
Autor:
Pejman Ghelich, Yi-Syuan Guo, Khanh Thi My Tran, Sharareh Emadi, Martin Han, Tiantian Guo, Longtu Chen, Nicholas F. Nolta, Bin Feng
Publikováno v:
Sens Actuators B Chem
The peripheral nervous system (PNS) is an attractive target for modulation of afferent input (e.g., nociceptive input signaling tissue damage) to the central nervous system. To advance mechanistic understanding of PNS neural encoding and modulation r
Autor:
Yuankai Huang, Amvrossios C. Bagtzoglou, Baikun Li, Sharareh Emadi, Farzaneh MahmoodPoor Dehkordy, Yan Li
Publikováno v:
Chemical Engineering Journal. 334:1383-1391
Anaerobic hydrogen production (AHP) is a biochemical process capable of producing hydrogen and fatty acids from organic substrates in acidogenic phase. Currently, almost all of anaerobic systems use centrally stirred mixing where the flow is essentia
Autor:
Casey Bednarz, Jayla Millender, Shunyi Li, Kevin W.-H. Lo, Joemart Contreras, Guleid Awale, Thinh T. Le, Thanh D. Nguyen, Eli J. Curry, Ritopa Das, Sharareh Emadi, Yang Liu, David W. Rowe, Xiaonan Xin
Publikováno v:
Nano Energy. 76:105028
Electrical stimulation (ES) has been shown to induce and enhance bone regeneration. By combining this treatment with tissue-engineering approaches (which rely on biomaterial scaffolds to construct artificial tissues), a replacement bone-graft with st
Ultrasound that is widely used in medical diagnosis has drawn growing interests as a noninvasive means of neuromodulation. Focused pulsed ultrasound (FPUS) effectively modulates neural encoding and transmission in the peripheral nervous system (PNS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb9ad7df9b7571330f9f2033817a98f
https://europepmc.org/articles/PMC6217852/
https://europepmc.org/articles/PMC6217852/
Autor:
Peter Burkhard, Karen M. Bingham Ferlez, Labdhi Seth, Sharareh Emadi, Zoltan Beck, Gary R. Matyas, Stephen A. Kaba, Derek M. Musser, Carl R. Alving, David E. Lanar
Publikováno v:
Vaccine.
We have developed FMP014, a vaccine candidate against Plasmodium falciparum malaria, which is comprised of 60 identical monomer protein chains that form an icosahedral shaped self-assembling protein nanoparticle (SAPN). Each monomer contains selected