Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sharafuddin Khairuddin"'
Autor:
Wing Shan Yu, Anna Chung-Kwan Tse, Li Guan, Jennifer Lok Yu Chiu, Shawn Zheng Kai Tan, Sharafuddin Khairuddin, Stephen Kugbere Agadagba, Amy Cheuk Yin Lo, Man-Lung Fung, Ying-Shing Chan, Leanne Lai Hang Chan, Lee Wei Lim
Publikováno v:
Brain Stimulation, Vol 15, Iss 3, Pp 843-856 (2022)
Background: Given that visual impairment is bi-directionally associated with depression, we examined whether transcorneal electrical stimulation (TES), a non-invasive treatment for visual disorders, can ameliorate depressive symptoms. Objective: The
Externí odkaz:
https://doaj.org/article/696f7d04a6344fbc99e7ba7393cf1e20
Autor:
Sharafuddin Khairuddin, Wei Ling Lim, Luca Aquili, Ka Chun Tsui, Anna Chung-Kwan Tse, Shehani Jayalath, Ruhani Varma, Trevor Sharp, Abdelhamid Benazzouz, Harry Steinbusch, Arjan Blokland, Yasin Temel, Lee Wei Lim
Publikováno v:
Cells, Vol 12, Iss 11, p 1449 (2023)
High-frequency stimulation (HFS) is a promising therapy for patients with depression. However, the mechanisms underlying the HFS-induced antidepressant-like effects on susceptibility and resilience to depressive-like behaviors remain obscure. Given t
Externí odkaz:
https://doaj.org/article/5b6883878c3048faa8369eb2c6f1ca84
Autor:
Tatyana Strekalova, Ekaterina Veniaminova, Evgeniy Svirin, Ekaterina Kopeikina, Tatyana Veremeyko, Amanda W. Y. Yung, Andrey Proshin, Shawn Zheng Kai Tan, Sharafuddin Khairuddin, Lee Wei Lim, Klaus-Peter Lesch, Susanne Walitza, Daniel C. Anthony, Eugene D. Ponomarev
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1759 (2021)
A deficiency in GM3-derived gangliosides, resulting from a lack of lactosylceramide-alpha-2,3-sialyltransferase (ST3GAL5), leads to severe neuropathology, including epilepsy and metabolic abnormalities. Disruption of ganglioside production by this en
Externí odkaz:
https://doaj.org/article/b5aba7368ea34b16b074c8815ed02464
Autor:
Sze Chun Chau, Pit Shan Chong, Hongkai Jin, Ka Chun Tsui, Sharafuddin Khairuddin, Anna Chung Kwan Tse, Sze Yuen Lew, George Lim Tipoe, Chi Wai Lee, Man-Lung Fung, Kah Hui Wong, Lee Wei Lim
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6089
Cerebellar ataxia is a neurodegenerative disorder with no definitive treatment. Although previous study demonstrated the neuroprotective effects of Hericium erinaceus (H.E.), the mechanisms of H.E. treatment on the neuroinflammatory response, neurotr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42026c510672f8ba196ed5030e2fa8c5
Chronic mild stress paradigm as a rat model of depression: facts, artifacts, and future perspectives
Autor:
Tatyana Strekalova, Yanzhi Liu, Daniel Kiselev, Sharafuddin Khairuddin, Jennifer Lok Yu Chiu, Justin Lam, Ying-Shing Chan, Dmitrii Pavlov, Andrey Proshin, Klaus-Peter Lesch, Daniel C. Anthony, Lee Wei Lim
Publikováno v:
Psychopharmacology
Rationale The chronic mild stress (CMS) paradigm was first described almost 40 years ago and has become a widely used model in the search for antidepressant drugs for major depression disorder (MDD). It has resulted in the publication of almost 1700
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8404092674d245f954d2a47252721572
https://doi.org/10.1007/s00213-021-05982-w
https://doi.org/10.1007/s00213-021-05982-w
Autor:
Kah-Hui Wong, Tze Lok Cecil Hoo, Lee Wei Lim, Luca Aquili, Sharafuddin Khairuddin, Boon Chin Heng
Publikováno v:
Neuroscience & Biobehavioral Reviews. 118:384-396
Orexins are highly involved in regulating the circadian rhythm, the brain's reward mechanism, and the neuroendocrine response to stress. The disruption of orexin regulation is known to be associated with depression. Preclinical studies in rodents hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd63f66dbe9a42cef95b93e2d0ac1a3e
https://doi.org/10.1016/j.neubiorev.2020.07.040
https://doi.org/10.1016/j.neubiorev.2020.07.040
Autor:
Evgeniy Svirin, Daniel C. Anthony, Eugene D. Ponomarev, Andrey Proshin, Amanda W. Y. Yung, Ekaterina Kopeikina, Shawn Zheng Kai Tan, Klaus-Peter Lesch, Tatyana Veremeyko, Sharafuddin Khairuddin, Tatyana Strekalova, Ekaterina Veniaminova, Susanne Walitza, Lee Wei Lim
Publikováno v:
Biomolecules
Biomolecules, 11(12):1759. Multidisciplinary Digital Publishing Institute (MDPI)
Biomolecules, Vol 11, Iss 1759, p 1759 (2021)
Biomolecules, 11(12):1759. Multidisciplinary Digital Publishing Institute (MDPI)
Biomolecules, Vol 11, Iss 1759, p 1759 (2021)
A deficiency in GM3-derived gangliosides, resulting from a lack of lactosylceramide-alpha-2,3-sialyltransferase (ST3GAL5), leads to severe neuropathology, including epilepsy and metabolic abnormalities. Disruption of ganglioside production by this en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a278f65cd7b143567993343a58f90a9e
https://doi.org/10.3390/biom11121759
https://doi.org/10.3390/biom11121759
Autor:
Man-Lung Fung, Sharafuddin Khairuddin, Naveed Ahmed Khan, Luca Aquili, Fung Yin Ngo, Lee Wei Lim, YS Chan, Wei Ling Lim, Yasin Temel
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 9, Iss 3260, p 3260 (2020)
Journal of Clinical Medicine, Vol 9, Iss 3260, p 3260 (2020)
Major depression contributes significantly to the global disability burden. Since the first clinical study of deep brain stimulation (DBS), over 446 patients with depression have now undergone this neuromodulation therapy, and 29 animal studies have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685209c9461a4b92f11c60763f72501a
https://shura.shu.ac.uk/27727/1/jcm-09-03260-v2.pdf
https://shura.shu.ac.uk/27727/1/jcm-09-03260-v2.pdf
Autor:
Lee Wei Lim, Sharafuddin Khairuddin, Man-Lung Fung, George L. Tipoe, Anna Chung-Kwan Tse, Kah-Hui Wong, Lih Fhung Hiew, Chun Lok Lau, Pit Shan Chong
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-18 (2020)
Cerebellar ataxia is a neurodegenerative disorder with no definitive treatment. Although several studies have demonstrated the neuroprotective effects of Hericium erinaceus (H.E.), its mechanisms in cerebellar ataxia remain largely unknown. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3091d73089fdbc7cfb67e8234823b580
https://pubmed.ncbi.nlm.nih.gov/32913245
https://pubmed.ncbi.nlm.nih.gov/32913245
Autor:
Junhao Koh, Sharafuddin Khairuddin, Wei Ling Lim, Lee Wei Lim, Man-Lung Fung, Luca Aquili, Lih Fhung Hiew
Publikováno v:
Behavioural brain research. 385
Measures of anxiety in behavioural tests remain largely unclear even decades after their establishment. Differences in the severity of anxiety measured by anxiety tests is an important issue that must be addressed. To test the hypothesis that the add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48dbdfab0b140951e3e3b4838d9bc40
https://pubmed.ncbi.nlm.nih.gov/32097707
https://pubmed.ncbi.nlm.nih.gov/32097707