Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sharadvi Thati"'
Publikováno v:
Pharmaceutics, Vol 4, Iss 2, Pp 276-295 (2012)
New lymphatic imaging technologies are needed to better assess immune function and cancer progression and treatment. Lymphatic uptake depends mainly on particle size (10–100 nm) and charge. The size of carriers for imaging and drug delivery can be
Externí odkaz:
https://doaj.org/article/f3848781833746238f2ef540780ddcd7
Autor:
Joshua O Sestak, Bradley P Sullivan, Sharadvi Thati, Laura Northrup, Brittany Hartwell, Lorena Antunez, M Laird Forrest, Charlotte M Vines, Teruna J Siahaan, Cory Berkland
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 1, Iss C (2014)
Autoimmune diseases such as multiple sclerosis (MS) are typified by the misrecognition of self-antigen and the clonal expansion of autoreactive T cells. Antigen-specific immunotherapies (antigen-SITs) have long been explored as a means to desensitize
Externí odkaz:
https://doaj.org/article/8ab9ff58c3e740d79df828ab13b98770
Autor:
Dhanushka B. Weerasekara, Jean R. Salash, Melissa M. Pressnall, Sharadvi Thati, J. Daniel Griffin, Matthew A. Christopher, Susan M. Lunte, Cory Berkland
Publikováno v:
Molecular Pharmaceutics. 16:607-617
Contemporary approaches to treating autoimmune diseases like Multiple Sclerosis broadly modulate the immune system and leave patients susceptible to severe adverse effects. Antigen-specific immunotherapies (ASIT) offer a unique opportunity to selecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094d53856e34f0b9fa74b9af1a3f17d0
https://doi.org/10.1021/acs.molpharmaceut.8b00887
https://doi.org/10.1021/acs.molpharmaceut.8b00887
Autor:
Melissa M. Pressnall, Cory Berkland, Stephanie N. Johnson, Chad J. Pickens, Bradley P. Sullivan, Martin A. Leon, Matthew A. Christopher, Sharadvi Thati
Publikováno v:
Mol Pharm
Multiple sclerosis represents the world's most common cause of neurological disability in young people and is attributed to a loss of immune tolerance toward proteins of the myelin sheath. Typical treatment options for MS patients involve immunomodul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e592de3d625738f0a07595abc55c45
https://pubmed.ncbi.nlm.nih.gov/31083955
https://pubmed.ncbi.nlm.nih.gov/31083955
Autor:
Nicholas R. Larson, Sharadvi Thati, Eduardo Rosa-Molinar, Jimmy Y. Song, Cory Berkland, Christian Schöneich, Martin A. Leon, C. Russell Middaugh, Noraida Martinez-Rivera, M. Laird Forrest, Irma Torres-Vazquez, Natalia Subelzu
Glatiramer acetate (GA) is widely prescribed for the treatment of relapsing-remitting multiple sclerosis, however, the mechanism of action is still not fully understood. We investigated the structural properties of GA and examined alterations to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d34cc733ec50f25cd467d2a1c0330113
https://europepmc.org/articles/PMC6372117/
https://europepmc.org/articles/PMC6372117/
Autor:
Sharadvi Thati, Joshua Sestak, Teruna J. Siahaan, Christopher Kuehl, Cory Berkland, Brittany L. Hartwell, M. Laird Forrest
Publikováno v:
Journal of Pharmaceutical Sciences. 104:714-721
Soluble Antigen Arrays (SAgAs) were developed for treating mice with experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis. SAgAs are composed of hyaluronan with grafted EAE antigen and LABL peptide (a ligand of ICAM-1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d56760db1fc9d12defe9165c2388af87
https://doi.org/10.1002/jps.24272
https://doi.org/10.1002/jps.24272
Autor:
Sharadvi Thati, Joshua Sestak, Bradley P. Sullivan, Brittany L. Hartwell, Lorena R. Antunez, Cory Berkland
Publikováno v:
Journal of Pharmaceutical Sciences. 104:346-361
Continued development of multivalent nanomaterials has provided opportunities for the advancement of antigen-specific immunotherapies. New insights emerge when considering the backdrop of vaccine design, which has long employed multivalent presentati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c7be9d61026c012c4d606ba9193c473
https://doi.org/10.1002/jps.24273
https://doi.org/10.1002/jps.24273
Autor:
Teruna J. Siahaan, Michael A. Thompson, Bradley P. Sullivan, Sharadvi Thati, Cory Berkland, Joshua Sestak, Christopher Kuehl
Publikováno v:
Journal of pharmaceutical sciences. 106(11)
Antigen-specific immunotherapy has been used to hyposensitize patients to allergens and offers an enticing approach for attenuating autoimmune diseases. Applying antigen-specific immunotherapy to mucosal surfaces such as the lungs may engage unique i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8f7862762481fa9ab2bcf9034e98993
https://pubmed.ncbi.nlm.nih.gov/28625726
https://pubmed.ncbi.nlm.nih.gov/28625726
Autor:
M. Laird Forrest, Teruna J. Siahaan, Laura Northrup, Joshua Sestak, Meagan Mullins, Sharadvi Thati, Cory Berkland
Publikováno v:
Journal of Controlled Release. 168:334-340
The immune response to antigens is directed in part by the presence or absence of costimulatory signals. The ability to coincidently present both antigen and, for example, a peptide that inhibits or activates the costimulatory pathway, would be a val
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a7361a4aa16204a968a16b21bccc43
https://doi.org/10.1016/j.jconrel.2013.03.015
https://doi.org/10.1016/j.jconrel.2013.03.015
Publikováno v:
Pharmaceutics, Vol 4, Iss 2, Pp 276-295 (2012)
Pharmaceutics
Pharmaceutics; Volume 4; Issue 2; Pages: 276-295
Pharmaceutics
Pharmaceutics; Volume 4; Issue 2; Pages: 276-295
New lymphatic imaging technologies are needed to better assess immune function and cancer progression and treatment. Lymphatic uptake depends mainly on particle size (10–100 nm) and charge. The size of carriers for imaging and drug delivery can be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265d163415a9bb570885cd13c39149c5
http://www.mdpi.com/1999-4923/4/2/276
http://www.mdpi.com/1999-4923/4/2/276