Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sharada Shenvi Labadie"'
Autor:
Taygerly Joshua Paul Gergely, Eun Kyung Lee, Mcintosh Joel, Sarah C. Abbot, Jaehyeon Park, Sonal Rajyaguru, Yun-Chou Tan, Shalini Anand, Francisco Xavier Talamas, Sophie Le Pogam, Remy Lemoine, David S. Carter, Petra Inbar, Jun Chen, Leanna R. Staben, Armando G. Villaseñor, Javier de Vicente, Isabel Najera, Ryan Craig Schoenfeld, Leyi Gong, Seth F. Harris, Paul Weller, Sharada Shenvi Labadie, Ken A. Brameld, Aruna Railkar, Sangi Michael, Amy Fung, Jim Li, Vincent Leveque, Dana Davis
Publikováno v:
Journal of Medicinal Chemistry. 57:1914-1931
In the past few years, there have been many advances in the efforts to cure patients with hepatitis C virus (HCV). The ultimate goal of these efforts is to develop a combination therapy consisting of only direct-antiviral agents (DAAs). In this paper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8b3c89c500a0233782f42b5f71c4d4
https://doi.org/10.1021/jm401329s
https://doi.org/10.1021/jm401329s
Publikováno v:
Synlett. 1995:655-658
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f45dc0225b4ffeecfe246861e063f10
https://doi.org/10.1055/s-1995-5029
https://doi.org/10.1055/s-1995-5029
Autor:
Sharada Shenvi Labadie
Publikováno v:
Synthetic Communications. 24:709-719
3,5-Dimethyl-4-iodoisoxazole readily undergoes palladium-catalyzed coupling with arylboronic acids and organostannanes to form 4-aryl-3,5-dimethylisoxazoles. The unique nature of the isoxazole-ring is exploited to convert 4-aryl-3,5-dimethylisoxazole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::388f40bdd9d6282b2384cbed39b9a35f
https://doi.org/10.1080/00397919408012650
https://doi.org/10.1080/00397919408012650
Autor:
Lars G.J. Hammarström, Sharada Shenvi Labadie, Nancy Elisabeth Krauss, David Bernard Smith, Francisco Xavier Talamas
Publikováno v:
Tetrahedron Letters. 43:8071-8073
4,6-Dichloro-2-(methylthio)-5-nitropyrimidine has been utilized as a building block for an efficient nine-step synthesis of olomoucine. The methodology reported herein is applicable to the regiocontrolled solution and solid-phase synthesis of librari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6129c3b991d2ffeb57d6aea7650a8561
https://doi.org/10.1016/s0040-4039(02)01953-6
https://doi.org/10.1016/s0040-4039(02)01953-6
Autor:
Gill Adrian Liam, Csaba Lehel, Mcintosh Joel, Francisco Xavier Talamas, Roland J. Billedeau, Holger Wesche, David Clark, Eric Brian Sjogren, Matt Wright, Nigel Walker, Stacie A. Dalrymple, Sharada Shenvi Labadie, Camran Parast, Timothy D. Cushing, George Tonn, Michelle F. Browner, Keith A. M. Walker, Viola Bordunov, Pu-Ping Lu, Marie-Louise Smith, Chris Whitehead, Xiao He, Mario G. Cardozo, Juan C. Jaen, Chris Allen Broka, Peng Cheng, Youngsook Shin, Karen Berry, Vijay Baichwal, Shichang Miao, Ronald Charles Hawley, Xiaolin Hao, Michael DeGraffenreid, Marc Labelle
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(1)
A novel series of (E)-1-((2-(1-methyl-1H-imidazol-5-yl) quinolin-4-yl) methylene) thiosemicarbazides was discovered as potent inhibitors of IKKβ. In this Letter we document our early efforts at optimization of the quinoline core, the imidazole and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc82bc82b7e7cf09330f7c5b4a3deba2
https://pubmed.ncbi.nlm.nih.gov/21074993
https://pubmed.ncbi.nlm.nih.gov/21074993
Autor:
Karen Berry, Viola Bordunov, Shichang Miao, David Clark, George Tonn, Timothy D. Cushing, Ronald Charles Hawley, Gill Adrian Liam, Marc Labelle, Csaba Lehel, Pu-Ping Lu, Francisco Xavier Talamas, Vijay Baichwal, Roland J. Billedeau, Mario G. Cardozo, Mcintosh Joel, Peng Cheng, Marie-Louise Smith, Michael DeGraffenreid, Chris Whitehead, Stacie A. Dalrymple, Xiao He, Nigel Walker, Camran Parast, Xiaolin Hao, Holger Wesche, Matt Wright, Eric Brian Sjogren, Keith A. M. Walker, Juan C. Jaen, Chris Allen Broka, Sharada Shenvi Labadie, Michelle F. Browner, Youngsook Shin
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(1)
A novel series of (E)-1-((2-(1-methyl-1H-imidazol-5-yl) quinolin-4-yl) methylene) thiosemicarbazides was discovered as potent inhibitors of IKKβ. In this Letter we document our efforts at further optimization of this series, culminating in 2 with su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf43c755172d814362bce5fc139f29d9
https://pubmed.ncbi.nlm.nih.gov/21074992
https://pubmed.ncbi.nlm.nih.gov/21074992
Autor:
Sharada Shenvi Labadie
Publikováno v:
ChemInform. 25
3,5-Dimethyl-4-iodoisoxazole readily undergoes palladium-catalyzed coupling with arylboronic acids and organostannanes to form 4-aryl-3,5-dimethylisoxazoles. The unique nature of the isoxazole-ring is exploited to convert 4-aryl-3,5-dimethylisoxazole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88c6c5f99ea4b2462b47f0fabe410cfa
https://doi.org/10.1002/chin.199441094
https://doi.org/10.1002/chin.199441094
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cff796898b05d295ebb6c4f3780ad02f
https://doi.org/10.1002/chin.199546148
https://doi.org/10.1002/chin.199546148
Autor:
Sharada Shenvi Labadie
Publikováno v:
ChemInform. 29
A short synthesis of multi-substituted benzothiophenes using the Alder-Rickert reaction is described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4c24256a599c9ddef918c2c2aae263f
https://doi.org/10.1002/chin.199839102
https://doi.org/10.1002/chin.199839102