Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sharada Prasad Yadav"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience
Cellular localization, assembly and abnormal aggregation of neurofilaments depend on phosphorylation. Pathological processes associated with neurodegeneration exhibit aberrant accumulation of microtubule associated aggregated forms of hyperphosphoryl
Publikováno v:
Biochemistry. 47:2134-2142
To investigate as to whether a peptide derived from hemolysin E (HlyE) can inhibit the cytotoxic activity of this protein or not, several peptides were examined for their efficacy to inhibit the lytic activity of the protein against human red blood c
Publikováno v:
Development (Cambridge, England)
Defects in cilia centrosomal genes cause pleiotropic clinical phenotypes, collectively called ciliopathies. Cilia biogenesis is initiated by the interaction of positive and negative regulators. Centriolar coiled coil protein 110 (CP110) caps the dist
Publikováno v:
Journal of Biological Chemistry. 279:55042-55050
Melittin, a naturally occurring antimicrobial peptide, exhibits strong lytic activity against both eukaryotic and prokaryotic cells. Despite a tremendous amount of work done, very little is known about the amino acid sequence, which regulates its tox
Publikováno v:
Journal of Biological Chemistry. 278:51023-51034
Hemolysin E (HlyE) is a 34 kDa protein toxin, recently isolated from a pathogenic strain of Escherichia coli, which is believed to exert its toxic activity via formation of pores in the target cell membrane. With the goal of understanding the involve
Autor:
Hong Hao, Sharada Prasad Yadav, Jung-Woong Kim, Benjamin E. Reese, Patrick W. Keeley, Raman Sood, Souparnika H. Manjunath, Bo Sun, Douglas S. Kim, Shobi Veleri, Hyun-Jin Yang, Anand Swaroop, Paul P. Liu
Publikováno v:
Human molecular genetics, vol 23, iss 16
The Maf-family leucine zipper transcription factor NRL is essential for rod photoreceptor development and functional maintenance in the mammalian retina. Mutations in NRL are associated with human retinopathies, and loss of Nrl in mice leads to a con
Autor:
Sharada Prasad Yadav, Marie-Audrey Ines Kautzmann, Jacob Nellissery, Hyun-Jin Yang, Martin Seifert, Matthew Brooks, Anand Swaroop, Bernward Klocke, Hong Hao
Publikováno v:
Human molecular genetics. 23(8)
Phototransduction machinery in vertebrate photoreceptors is contained within the membrane discs of outer segments. Daily renewal of 10% of photoreceptor outer segments requires stringent control of gene expression. Rhodopsin constitutes over 90% of t
Autor:
Aqeel Ahmad, Jimut Kanti Ghosh, Sharada Prasad Yadav, Richa Verma, Brijesh K. Pandey, Dharamsheela Singh, Raj Kamal Tripathi, Neeta Asthana
Publikováno v:
Biochimica et biophysica acta. 1788(2)
Hemolysin E (HlyE), a pore-forming protein-toxin and a potential virulence factor of Escherichia coli , exhibits cytotoxic activity to mammalian cells. However, very little is known about how the different individual segments contribute in the toxic
Publikováno v:
Biochimica et biophysica acta. 1768(6)
To find out the sequence requirement of the H-205 peptide, containing an amphipathic leucine zipper motif corresponding to the amino acid (a.a.) region 205–234 of hemolysin E (HlyE) to induce efficient permeation in zwitterionic lipid vesicles, the
Autor:
Swati Prakash Srivastava, Aqeel Ahmad, Jimut Kanti Ghosh, Kalyan Mitra, Sharada Prasad Yadav, Neeta Asthana
Publikováno v:
The Journal of biological chemistry. 281(31)
The toxicity of naturally occurring or designed antimicrobial peptides is a major barrier for converting them into drugs. To synthesize antimicrobial peptides with reduced toxicity, several amphipathic peptides were designed based on the leucine zipp