Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sharada H. Sharma"'
Publikováno v:
European Journal of Cancer Prevention. 28:472-482
Suppression of colorectal cancer by means of chemoprevention is gaining great attention owing to promising outcomes with less adverse effects in preclinical and clinical trials. The present study aims to explore the mechanism of chemoprevention by p-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a89107914910b695d2fab38ad235044
https://doi.org/10.1097/cej.0000000000000496
https://doi.org/10.1097/cej.0000000000000496
Publikováno v:
Toxicology mechanisms and methods. 30(4)
Angiogenesis, disturbance in redox homeostasis, and deregulated redox signaling are considered as common hallmarks of cancer progression and chemo resistance. In this context, PERK (protein kinase PKR-like ER kinase) branch of the unfolded protein re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9264b8f06474ac3277466df362eba9c7
https://pubmed.ncbi.nlm.nih.gov/32028820
https://pubmed.ncbi.nlm.nih.gov/32028820
Publikováno v:
Biomedicine & Pharmacotherapy. 100:367-373
Colorectal cancer is the third most common cancer worldwide. The development of effective, inexpensive and safe chemopreventive agents would be of great benefit as it involves use of natural products to prevent or suppress the progression of precurso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359834d9c14d3eb1e9e70319645fbd9e
https://doi.org/10.1016/j.biopha.2018.02.035
https://doi.org/10.1016/j.biopha.2018.02.035
Publikováno v:
Biomedicine & Pharmacotherapy. 94:577-588
Oxidative stress and gut microbial enzymes are intricately linked to the onset of colon carcinogenesis. Phytochemicals that modulate these two factors hold promise for the development of such agents as anticancer drugs. The present study evaluates th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d001cc7d1d94d40d4a47f6c4abd7459
https://doi.org/10.1016/j.biopha.2017.07.146
https://doi.org/10.1016/j.biopha.2017.07.146
Publikováno v:
European Journal of Pharmacology. 795:169-178
Multistep model of colon carcinogenesis has provided the framework to advance our understanding of the molecular basis of colon cancer. This multistage process of carcinogenesis takes a long period to transform from a normal epithelial cell to invasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f77f8629d236d822dc824efe4e52d0
https://doi.org/10.1016/j.ejphar.2016.12.008
https://doi.org/10.1016/j.ejphar.2016.12.008
Publikováno v:
Chemico-biological interactions. 291
p-CA is a naturally occurring phenolic acid present in most plants and in all commonly consumed vegetables and fruits. Here we demonstrated the anti-cancer effect of the food borne phytochemical p-CA both in vitro and in vivo models of colon cancer u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d80c0702e3022e225a5c1ed375eff22
https://pubmed.ncbi.nlm.nih.gov/29879413
https://pubmed.ncbi.nlm.nih.gov/29879413
Autor:
Prabu Chinnaswamy, David Raj Chellappan, Sharada H. Sharma, Senthilkumar Thulasingam, Sangeetha Nagarajan
Publikováno v:
European journal of pharmacology. 796
Targeting tumor metabolism by natural products is a novel approach and provides rationale for anti-cancer drug discovery. The present study aims to explore the impact of morin and/or esculetin on c-myc induced energy metabolism in 1,2-dimethylhydrazi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b51d3df7ad989fa41a613bae160862
https://pubmed.ncbi.nlm.nih.gov/27989504
https://pubmed.ncbi.nlm.nih.gov/27989504
Publikováno v:
Life sciences. 145
Recent studies have shown that tumor development and progression depend not only on the perturbed genes that govern cell proliferation, but is also highly determined by the non-tumor cells of the stromal compartment surrounding the tumor called tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b10a848dfa43364268d7dadfc6eb87e
https://pubmed.ncbi.nlm.nih.gov/26679106
https://pubmed.ncbi.nlm.nih.gov/26679106