Výsledky vyhledávání - "Sharad V. Kuberkar"

Akademický článek

A convenient synthesis of 3-cyano-4-imino-2-methylthio-4H-pyrimido [2,1-b] [1,3] benzothiazole and its reactions with selected nucleophiles

Autor: Mayura S. Pingle, Sambhaji P. Vartale, Vijay N. Bhosale, Sharad V. Kuberkar

Publikováno v: ARKIVOC, Vol 2006, Iss 10, Pp 190-198 (2006)

Externí odkaz: https://doaj.org/article/2c704c7492454c8cb0cac63423afb604

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Synthesis and Pharmacological Evaluation of Tetrazolobenzimidazoles as Novel Anti-inflammatory Agents

Autor: Rajesh B. Nawale, Manjiri R. Peharkar, Mayura A. Kale, Sharad V. Kuberkar

Publikováno v: Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry. 15:118-126

Background: Currently used anti-inflammatory drugs are associated with some severe side effects such as gastric irritation, which may range from simple discomfort to ulcer formation. Therefore, the development of potent anti-inflammatory drugs with f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64ac4809fdac47ab13ec67131577fa72
https://doi.org/10.2174/1871523015666160915153904

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Synthesis and in-vitro anticancer activity of 3-cyano-6,9-dimethyl-4-imino 2-methylthio 4H-pyrimido [2,1-b] [1,3] benzothiazole and its 2-substituted derivatives

Autor: Vijay N. Bhosale, Giridhar R. Shendarkar, Anil B. Chidrawar, Gangadhar S. Waghmare, Sharad V. Kuberkar

Publikováno v: Journal of Pharmacy Research. 7:823-827

Aim Novel heterocycle 3-cyano 6,9-dimethyl 4-imino 2-methylthio 4H pyrimido [2,1- b ] [1,3] benzothiazole 3 has been prepared by using 2-amino 4,7-dimethtyl benzothiazole 1 and bis-methylthio methylene malononitrile 2. Method Compound 3 prepared from

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c4b54f39eae4d0f035b2c601549474e7
https://doi.org/10.1016/j.jopr.2013.08.028

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Novel synthesis and biological activity of 2-substituted derivatives of 3-cyano-4-imino-2-methylthio-8-methoxy-4H-pyrimido[2,1-b][1,3]benzothiazole and 3-amino-4-imino-8-methoxy-2H-pyrazolo[3′,4′:4,5]pyrimido[2,1-b][1,3]benzothiazole

Autor: S. G. Badne, Vijay N. Bhosale, Sharad V. Kuberkar, D. K. Swamy

Publikováno v: Journal of Heterocyclic Chemistry. 48:849-855

2-Amino-6-methoxybenzothiazole 1 on reaction with bis(methylthio)methylene malononitrile 2 in the presence of dimethyl formamide and catalytic amount of anhydrous potassium carbonate afforded 3-cyano-4-imino-8-methoxy-4H-pyrimido[2,1-b][1,3]benzothia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8118ef6941198ad291895b799c7b857a
https://doi.org/10.1002/jhet.559

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Synthesis and some novel reactions of 8-chloro-2H-[1,2,4]triazino[3,4-b] [1,3]benzothiazole-3,4-dione and 6-chloro-2-hydrazino-1,3-benzothiazole

Autor: Santosh G. Badne, Sambhaji P. Vartale, Sharad V. Kuberkar, Vijay N. Bhosale

Publikováno v: Journal of Chemical Research. 2005:632-635

3,8-Dichloro-4H-[1,2,4]triazino[3,4-b][1,3]benzothiazole-4-one on reaction independently with sodium hydroxide solution and sodium azide undergo novel ring contraction reactions to give 7-chloro[1,2,4]triazolo[3,4-b][1,3] benzothiazole and 8-chloro t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc4159e58815d3595734b4f4fbefdde0
https://doi.org/10.3184/030823405774663084

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ChemInform Abstract: Novel Synthesis and Biological Activity of 2-Substituted Derivatives of 3-Cyano-4-imino-2-methylthio-8-methoxy-4H-pyrimido[2,1-b] [1,3]benzothiazole and 3-Amino-4-imino-8-methoxy-2H-pyrazolo[3′,4′:4,5]pyrimido[2,1-b] [1,3]benzothiazol

Autor: Vijay N. Bhosale, Sharad V. Kuberkar, S. G. Badne, D. K. Swamy

Publikováno v: ChemInform. 42

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8600d5732aa61a9b94a26e6b0ad96421
https://doi.org/10.1002/chin.201151155

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Exploring CYP1A1 as anticancer target: homology modeling and in silico inhibitor design

Autor: Sharad v. Kuberkar, Abhay T. Sangamwar, Leena B. Labhsetwar

Publikováno v: Journal of molecular modeling. 14(11)

Microsomal cytochrome P450 family 1 enzymes has great importance in the bioactivation of mutagens. P450 catalyzed reactions involve a wide range of substrates, and this versatality is reflected in a structural diversity, evident in the active sites o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aee377b431341e6d3e7e2337659c0239
https://pubmed.ncbi.nlm.nih.gov/18665399

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