Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Sharad Kumar Suthar"'
Autor:
Sharad Kumar Suthar, Sang-Yoon Lee
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Despite the knowledge that mutation, multiplication, and anomalous function of α-synuclein cause progressive transformation of α-synuclein monomers into toxic amyloid fibrils in neurodegenerative diseases, the understanding of canonical signaling,
Externí odkaz:
https://doaj.org/article/1d74ffa6bfdd447197b7b0e792225c33
Autor:
Sharad Kumar Suthar, Sang-Yoon Lee
Publikováno v:
Brain Sciences, Vol 13, Iss 1, p 151 (2023)
Mutations in superoxide dismutase 1 (SOD1) result in misfolding and aggregation of the protein, causing neurodegenerative amyotrophic lateral sclerosis (ALS). In recent years, several new SOD1 variants that trigger ALS have been identified, making it
Externí odkaz:
https://doaj.org/article/99bff9e00b704cb38a6059b99e8a04b4
Autor:
Sharad Kumar Suthar, Mohammad Maqusood Alam, Jihye Lee, Jitender Monga, Alex Joseph, Sang-Yoon Lee
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
TSPO-associated protein 1 (TSPOAP1) is a cytoplasmic protein and is closely associated with its mitochondrial transmembrane protein partner translocator protein (TSPO). To decipher the canonical signalling pathways of TSPOAP1, its role in human disea
Externí odkaz:
https://doaj.org/article/35e4304558f943159a5053b80dbd4f1d
Autor:
Zsolt Borhegyi, Kinga Oravecz, László Kornya, Sharad Kumar Suthar, Ádám Kiss, Máté Déri, Suman Nag, Jacob L. Krans, Katalin Monostory, Máté Gyimesi, Kamirán Á. Hamow, András Málnási-Csizmadia, Ivan Tomasic, István Lőrincz, Patrick J. Tierney, Anna Á. Rauscher, Mihály Kovács, Pál Szabó
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 376:358-373
Blebbistatin, para-nitroblebbistatin (NBleb), and para-aminoblebbistatin (AmBleb) are highly useful tool compounds as they selectively inhibit the ATPase activity of myosin-2 family proteins. Despite the medical importance of the myosin-2 family as d
Autor:
Ajay Hooda, Manu Sharma, Ankesh Sharma, Sumit Bansal, Monika Chauhan, Jitender Monga, Sharad Kumar Suthar
Publikováno v:
Natural Product Research. 35:3939-3944
A simple and economical method was developed for the extraction and isolation of pentacyclic triterpenoid lantadene A from the leaves of Lantana camara. The lantadene A displays significant anti-in...
Autor:
Jitender Monga, Sharad Kumar Suthar, Deepak Rohila, Alex Joseph, Chetan Singh Chauhan, Manu Sharma
Publikováno v:
Phytomedicine. 101:154116
Despite recent advances in the treatment of squamous cell skin cancer (SCSC), the disease persists, and treatment resistance develops. Thus, identifying new targets and developing new therapeutic approaches showing low vulnerability to drug resistanc
Autor:
Mate Gyimesi, Adam I. Horvath, Demeter Turos, Sharad Kumar Suthar, Mate Penzes, Louise Canon, Carlos Kikuti, Kathleen Ruppel, Darshan V. Trivedi, James A. Spudich, Anna Á. Rauscher, Mihaly Kovacs, Samuel Komoly, Anne M. Houdusse, Andras Malnasi-Csizmadia
Publikováno v:
Biophysical Journal. 121:291a
Autor:
Sharad Kumar, Suthar, Ajay, Hooda, Ankesh, Sharma, Sumit, Bansal, Jitender, Monga, Monika, Chauhan, Manu, Sharma
Publikováno v:
Natural product research. 35(21)
A simple and economical method was developed for the extraction and isolation of pentacyclic triterpenoid lantadene A from the leaves of
Autor:
Mate Winternitz, András Málnási-Csizmadia, Sharad Kumar Suthar, Máté Gyimesi, Anna Á. Rauscher
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 204:114246
Simple and consistent chiral HPLC methods for the efficient separation of enantiomeric blebbistatin derivatives, namely parent compound blebbistatin and derivatives 4-nitroblebbistatin, 4-aminoblebbistatin, 4-dimethylaminoblebbistatin, and 4-t-butylb
Autor:
Ádám I. Horváth, András Málnási-Csizmadia, Sharad Kumar Suthar, Máté Gyimesi, Mihály Kovács, Demeter Túrós, György Hegyi
Publikováno v:
Biophysical Journal. 118:434a