Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Sharad K. Sharma"'
Publikováno v:
PLOS Global Public Health, Vol 3, Iss 1 (2023)
Birth registration, an essential component of the civil registration system, is expected to be complete and universal. This study assesses the progress made in recent years and identifies gaps in birth registration in Nepal. Data from the Multiple In
Externí odkaz:
https://doaj.org/article/0c0143c99cee48059297551670d2dd31
Autor:
George H. Addona, David Jonathan Bennett, Brian J. Long, Sheila Ranganath, Anuradha Khilnani, Archie Tse, B. Wesley Trotter, Jared Cumming, Saso Cemerski, Ian Knemeyer, Vincenzo Pucci, Hyun Chong Woo, Sharad K. Sharma, Shuxia Zhao, Bo-Sheng Pan, Jennifer Piesvaux, Heidi M. Ferguson, Ellen C. Minnihan, Sarah Javaid, Manjiri Sathe, Jeremy Presland, Long Cui, Yiping Chen, Kalyan Chakravarthy, Jason Laskey, Eric S. Muise, Yanhong Ma, Johnny E. Kopinja, Samanthi A. Perera
Supplemental Figure 2: STING agonists stimulate cytokines in tumor, plasma and peripheral tissues following IT dosing.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fcaf4831f75b8eb5c4beefa54ae209
https://doi.org/10.1158/1535-7163.22522690.v1
https://doi.org/10.1158/1535-7163.22522690.v1
Autor:
George H. Addona, David Jonathan Bennett, Brian J. Long, Sheila Ranganath, Anuradha Khilnani, Archie Tse, B. Wesley Trotter, Jared Cumming, Saso Cemerski, Ian Knemeyer, Vincenzo Pucci, Hyun Chong Woo, Sharad K. Sharma, Shuxia Zhao, Bo-Sheng Pan, Jennifer Piesvaux, Heidi M. Ferguson, Ellen C. Minnihan, Sarah Javaid, Manjiri Sathe, Jeremy Presland, Long Cui, Yiping Chen, Kalyan Chakravarthy, Jason Laskey, Eric S. Muise, Yanhong Ma, Johnny E. Kopinja, Samanthi A. Perera
Supplementary Methods and Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3debc597dc269548a67fe876b174413a
https://doi.org/10.1158/1535-7163.22522684
https://doi.org/10.1158/1535-7163.22522684
Autor:
George H. Addona, David Jonathan Bennett, Brian J. Long, Sheila Ranganath, Anuradha Khilnani, Archie Tse, B. Wesley Trotter, Jared Cumming, Saso Cemerski, Ian Knemeyer, Vincenzo Pucci, Hyun Chong Woo, Sharad K. Sharma, Shuxia Zhao, Bo-Sheng Pan, Jennifer Piesvaux, Heidi M. Ferguson, Ellen C. Minnihan, Sarah Javaid, Manjiri Sathe, Jeremy Presland, Long Cui, Yiping Chen, Kalyan Chakravarthy, Jason Laskey, Eric S. Muise, Yanhong Ma, Johnny E. Kopinja, Samanthi A. Perera
Supplemental Table 1: Log2Ratio and p values for all 310 genes shown in Figure 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5490569e56c5aaab6a439f8f48897ab7
https://doi.org/10.1158/1535-7163.22522681.v1
https://doi.org/10.1158/1535-7163.22522681.v1
Autor:
Maciej M. Markiewski, Magdalena Karbowniczek, Othon Almanza, Wojciech Gorczyca, David P. Fairlie, Sasikanth Manne, Linley Riediger, Clayton Cleveland, Priya Sharma, Sharad K. Sharma, Navin K. Chintala, Surya Kumari Vadrevu
PDF file - 209KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::433209b2814aba2b923b2655e0b17b3d
https://doi.org/10.1158/0008-5472.22404069
https://doi.org/10.1158/0008-5472.22404069
Autor:
Maciej M. Markiewski, Magdalena Karbowniczek, Othon Almanza, Wojciech Gorczyca, David P. Fairlie, Sasikanth Manne, Linley Riediger, Clayton Cleveland, Priya Sharma, Sharad K. Sharma, Navin K. Chintala, Surya Kumari Vadrevu
PDF file - 85KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c30130999f0a914aa452ed4e31a33c4
https://doi.org/10.1158/0008-5472.22404075
https://doi.org/10.1158/0008-5472.22404075
Autor:
Maciej M. Markiewski, Magdalena Karbowniczek, Othon Almanza, Wojciech Gorczyca, David P. Fairlie, Sasikanth Manne, Linley Riediger, Clayton Cleveland, Priya Sharma, Sharad K. Sharma, Navin K. Chintala, Surya Kumari Vadrevu
PDF file - 981KB, Liver metastasis, C5aR expression on myeloid, 4T1 and T cells, infiltration of CD8+ T cells and MDSCs in livers of breast tumor-bearing mice (S1). MDSCs infiltrate lungs of breast tumor bearing mice prior to metastases (S2). Complem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e89bf89b860017f07f1d461dfb6bfdc
https://doi.org/10.1158/0008-5472.22404072
https://doi.org/10.1158/0008-5472.22404072
Publikováno v:
Pediatric allergy, immunology, and pulmonology. 26(1)
Newborns and young children rely on innate immunity to protect against infections until the adaptive immune system matures. Immunization helps facilitate protection, but multiple doses are needed to establish sufficient antibody levels and T-cell-fac
Autor:
Saso Cemerski, Jennifer Piesvaux, Jason Laskey, Brian Long, B. Wesley Trotter, Jared N. Cumming, Shuxia Zhao, Eric S. Muise, Yanhong Ma, Ellen C. Minnihan, Samanthi A. Perera, Sheila Ranganath, Sarah Javaid, Bo-Sheng Pan, Sharad K. Sharma, Yiping Chen, Jeremy Presland, Long Cui, Manjiri Sathe, Archie Tse, Kalyan Chakravarthy, Vincenzo Pucci, Ian Knemeyer, Hyun Chong Woo, David Jonathan Bennett, Anuradha D. Khilnani, George H. Addona, Heidi Ferguson, Johnny E. Kopinja
Publikováno v:
Molecular cancer therapeutics. 21(2)
The innate immune agonist STING (STimulator of INterferon Genes) binds its natural ligand 2′3′-cGAMP (cyclic guanosine-adenosine monophosphate) and initiates type I IFN production. This promotes systemic antigen-specific CD8+ T-cell priming that
Autor:
Laura Price, Samanthi A. Perera, Daniel F. Wyss, Johnny E. Kopinja, Saso Cemerski, Sharad K. Sharma, Timothy J. Henderson, Serena Xu, Andrew M. Haidle, Min Lu, George H. Addona, Greg O’Donnell, Berengere Sauvagnat, Gottfried K. Schroeder, Ilona Kariv, Larissa Rakhilina, Sriram Tyagarajan, Bo-Sheng Pan, Hyun Chong Woo, Brian Long, Jared N. Cumming, Brandon Cash, Yiping Chen, Ryan D. Otte, B. Wesley Trotter, Jeremy Presland, Jennifer Piesvaux, Brian M. Lacey, Rui Liang, Peter J. Dandliker, Ellen C. Minnihan, Charles A. Lesburg, Ian Knemeyer, Yanhong Ma, Guo Feng, David Jonathan Bennett, Michael D. Altman, Alexei V. Buevich, Jason Laskey, James P. Jewell, Wonsuk Chang
Publikováno v:
Signal Transduction and Targeted Therapy
Pharmacological activation of the STING (stimulator of interferon genes)-controlled innate immune pathway is a promising therapeutic strategy for cancer. Here we report the identification of MSA-2, an orally available non-nucleotide human STING agoni