Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Sharad K. Mittal"'
Autor:
Mingshun Lee, Elsayed Elbasiony, Wonkyung J. Cho, Vinay K. Pulimamidi, Olufemi S. Folorunso, Sharad K. Mittal, Reza Dana, Sunil K. Chauhan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Different therapeutic modalities, including steroids, have been used to treat corneal scarring. However, the ability of steroids to reduce corneal scarring is limited and associated with numerous side effects. Our previous studies have demon
Externí odkaz:
https://doaj.org/article/7f9f9d437de3417d8e072498f628253d
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Keratitis induced by bacterial toxins, including lipopolysaccharide (LPS), is a major cause of corneal opacity and vision loss. Our previous study demonstrates hepatocyte growth factor (HGF) promotes epithelial wound healing following mechan
Externí odkaz:
https://doaj.org/article/1e0b335af2e940a69638ebd7eb4d8ba1
Autor:
Sharad K. Mittal, William Foulsham, Sachin Shukla, Elsayed Elbasiony, Masahiro Omoto, Sunil K. Chauhan
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 10, Pp 1030-1040 (2019)
Abstract Mesenchymal stromal cells (MSCs) are multipotent stem cells that participate in tissue repair and possess considerable immunomodulatory potential. MSCs have been shown to promote allograft survival, yet the mechanisms behind this phenomenon
Externí odkaz:
https://doaj.org/article/cacc75198e384647935177e5aa3be9be
Autor:
William Foulsham, Sharad K. Mittal, Takeshi Nakao, Giulia Coco, Yukako Taketani, Sunil K. Chauhan, Reza Dana
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Abstract Adenosine triphosphate (ATP) is released into the extracellular environment during transplantation, and acts via purinergic receptors to amplify the alloimmune response. Here, using a well-established murine model of allogeneic corneal trans
Externí odkaz:
https://doaj.org/article/ab2e2f2678754b1596ab77c1e6dae7fd
Autor:
Xiaoxiao Lu, Abirami Kugadas, Kirsten Smith-Page, Jeffrey Lamb, Tiffany Lin, Yusha Ru, Sharon Celeste Morley, Raina Fichorova, Sharad K. Mittal, Sunil K. Chauhan, Sejiro Littleton, Daniel Saban, Mihaela Gadjeva
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Why ocular mucosa is paucibacterial is unknown. Many different mechanisms have been suggested but the comprehensive experimental studies are sparse. We found that a deficiency in L-plastin (LCP1), an actin bundling protein, resulted in an ocular comm
Externí odkaz:
https://doaj.org/article/aec72e9a91194cf59bd2689b12f81611
Autor:
Sharad K. Mittal, Masahiro Omoto, Afsaneh Amouzegar, Anuradha Sahu, Alexandra Rezazadeh, Kishore R. Katikireddy, Dhvanit I. Shah, Srikant K. Sahu, Sunil K. Chauhan
Publikováno v:
Stem Cell Reports, Vol 7, Iss 4, Pp 583-590 (2016)
Transparency of the cornea is indispensable for optimal vision. Ocular trauma is a leading cause of corneal opacity, leading to 25 million cases of blindness annually. Recently, mesenchymal stem cells (MSCs) have gained prominence due to their inflam
Externí odkaz:
https://doaj.org/article/4ef1513cc5a346609b252ade2bd01736
Publikováno v:
Stem Cells Translational Medicine. 12:221-233
Mounting evidence suggests mesenchymal stromal cells (MSCs) suppress CD4+ T-cell activation, but whether MSCs directly regulate activation and expansion of allogeneic T cells has not been fully deciphered. Here, we identified that both human and muri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99873ea188f9dcd6add85f37d0da2052
https://doi.org/10.1093/stcltm/szad012
https://doi.org/10.1093/stcltm/szad012
Autor:
Sharad K. Mittal, WonKyung Cho, Elsayed Elbasiony, Yilin Guan, William Foulsham, Sunil K. Chauhan
Publikováno v:
American Journal of Transplantation. 22:1564-1577
Mesenchymal stem cells (MSCs) and regulatory T cells (Tregs) both have been shown to modulate the alloimmune response and promote transplant survival. Mounting evidence suggests that MSCs augment Treg function, but the mechanisms underlying this phen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99681b8f3dd264d81b579b758833485f
https://doi.org/10.1111/ajt.17001
https://doi.org/10.1111/ajt.17001
Autor:
Elsayed Elbasiony, WonKyung J. Cho, Aastha Singh, Sharad K. Mittal, Driss Zoukhri, Sunil K. Chauhan
Publikováno v:
npj Aging. 9
The lacrimal gland undergoes significant structural and functional deterioration with aging. Marked with increased inflammation and fibrosis, the aged lacrimal gland is unable to perform its protective function. As a result, the ocular surface become
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::973c887989a146c0a95b4a5a16b399da
https://doi.org/10.1038/s41514-023-00099-0
https://doi.org/10.1038/s41514-023-00099-0
Publikováno v:
The American Journal of Pathology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b80e4ced1416cced83a3adcf61fd124e
https://doi.org/10.1016/j.ajpath.2023.01.003
https://doi.org/10.1016/j.ajpath.2023.01.003