Epidemiology and Outcomes of Antibiotic De-escalation in Patients with Suspected Sepsis in US Hospitals.

Autor: Kam KQ; Department of Population Medicine, Harvard Pilgrim Health Care Institute, Boston, MA, USA.; Infectious Disease Service, Department of Pediatrics, KK Women's & Children's Hospital, Singapore, Singapore.; SingHealth Duke-NUS Pediatrics Academic Clinical Program (ACP), Duke-NUS Medical School, Singapore, Singapore., Chen T; Department of Population Medicine, Harvard Pilgrim Health Care Institute, Boston, MA, USA., Kadri SS; Critical Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, MD.; Critical Care Medicine Branch, National Heart Lung and Blood Institute, Bethesda, MD., Lawandi A; Critical Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, MD.; Division of Infectious Diseases, Department of Medicine, McGill University Health Centre, Quebec, Canada., Yek C; Critical Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, MD.; Critical Care Medicine Branch, National Heart Lung and Blood Institute, Bethesda, MD., Walker M; Critical Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, MD.; Critical Care Medicine Branch, National Heart Lung and Blood Institute, Bethesda, MD., Warner S; Critical Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, MD.; Critical Care Medicine Branch, National Heart Lung and Blood Institute, Bethesda, MD., Fram D; Commonwealth Informatics, Waltham, MA, USA., Chen HC; Commonwealth Informatics, Waltham, MA, USA., Shappell CN; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., DelloStritto L; Department of Population Medicine, Harvard Pilgrim Health Care Institute, Boston, MA, USA., Jin R; Department of Population Medicine, Harvard Pilgrim Health Care Institute, Boston, MA, USA., Klompas M; Department of Population Medicine, Harvard Pilgrim Health Care Institute, Boston, MA, USA.; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Rhee C; Department of Population Medicine, Harvard Pilgrim Health Care Institute, Boston, MA, USA.; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2024 Dec 06. Date of Electronic Publication: 2024 Dec 06.

Trends in antibiotic utilization for patients hospitalized with COVID-19 with and without signs of sepsis.

Autor: Shappell CN; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Klompas M; Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, MA, USA.; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Chan C; Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, MA, USA., Chen T; Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, MA, USA., Rhee C; Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, MA, USA.; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.

Publikováno v: Antimicrobial stewardship & healthcare epidemiology : ASHE [Antimicrob Steward Healthc Epidemiol] 2024 Oct 03; Vol. 4 (1), pp. e143. Date of Electronic Publication: 2024 Oct 03 (Print Publication: 2024).

Use of Electronic Clinical Data to Track Incidence and Mortality for SARS-CoV-2-Associated Sepsis.

Autor: Shappell CN; Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, Massachusetts.; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts., Klompas M; Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, Massachusetts.; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts., Chan C; Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, Massachusetts., Chen T; Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, Massachusetts., Kanjilal S; Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, Massachusetts.; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts., McKenna C; Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, Massachusetts., Rhee C; Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, Massachusetts.; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

Publikováno v: JAMA network open [JAMA Netw Open] 2023 Sep 05; Vol. 6 (9), pp. e2335728. Date of Electronic Publication: 2023 Sep 05.

Do Prolonged Infusions of β-Lactam Antibiotics Improve Outcomes in Critically Ill Patients With Sepsis?

Autor: Shappell CN; Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts.; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts., Klompas M; Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts.; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts., Rhee C; Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts.; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

Publikováno v: JAMA [JAMA] 2023 Jul 11; Vol. 330 (2), pp. 126-128.

Quantifying the Burden of Viral Sepsis During the Coronavirus Disease 2019 Pandemic and Beyond.

Autor: Shappell CN; Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, MA.; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA., Klompas M; Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, MA.; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, MA., Rhee C; Department of Population Medicine, Harvard Medical School/Harvard Pilgrim Health Care Institute, Boston, MA.; Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, MA.

Publikováno v: Critical care medicine [Crit Care Med] 2021 Dec 01; Vol. 49 (12), pp. 2140-2143.