Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Shaozhi Fu"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background The combination of immune checkpoint inhibitors with radiotherapy can enhance the immunomodulation by RT and reduce the growth of distant unirradiated tumors (abscopal effect); however, the results are still not very satisfactory.
Externí odkaz:
https://doaj.org/article/0e3b46e589f74c6784ae1b2936175882
Autor:
Jie Dai, Jianmei Li, Yuqin Zhang, Qian Wen, Yun Lu, Yu Fan, Fancai Zeng, Zhiyong Qian, Yan Zhang, Shaozhi Fu
Publikováno v:
Biomaterials Research, Vol 27, Iss 1, Pp 1-17 (2023)
Abstract Background Hypoxia is a frequent characteristic observed in solid tumors and is strongly associated with tumor metastasis, angiogenesis, and drug resistance. While the vasculature of hypoxic tumor tissues poses obstacles to the efficient adm
Externí odkaz:
https://doaj.org/article/e65594f1c0334251a0b0739c64838dc9
Autor:
Yun Lu, Lan Chen, Zhouxue Wu, Ping Zhou, Jie Dai, Jianmei Li, Qian Wen, Yu Fan, Fancai Zeng, Yue Chen, Shaozhi Fu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 169, Iss , Pp 115846- (2023)
Breast cancer is characterized by insidious onset, rapid progression, easy recurrence, and metastasis. Conventional monotherapies are usually ineffective due to insufficient drug delivery. Therefore, the combination of multimodal therapy with tumor m
Externí odkaz:
https://doaj.org/article/0d8217ba5e594da38be50b0546ec31c3
Autor:
Susu Xiao, Yu Wang, Wenqiong Ma, Ping Zhou, Biqiong Wang, Zhouxue Wu, Qian Wen, Kang Xiong, Yanlin Liu, Shaozhi Fu
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 2713-2722 (2022)
Malignant ascites is a common complication of some advanced cancers. Although intraperitoneal (IP) administration of chemotherapy drugs is routinely used to treat cancerous ascites, conventional drugs have poor retention and therefore need to be admi
Externí odkaz:
https://doaj.org/article/2886d4ba08cd4e3d95541eb0a0cb8416
Autor:
Jing Wang, Yan Zhang, GuangPeng Zhang, Li Xiang, HaoWen Pang, Kang Xiong, Yun Lu, JianMei Li, Jie Dai, Sheng Lin, ShaoZhi Fu
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 588-599 (2022)
Chemotherapy is the primary treatment for advanced non-small-cell lung cancer (NSCLC). However, related dose-dependent toxicity limits its clinical use. Therefore, it is necessary to explore new strategies for improving the clinical outcomes while re
Externí odkaz:
https://doaj.org/article/4b2459a85baf49588da1071d5389bb5d
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionZinc finger and SCAN domain-containing protein 18 (ZSCAN18) has been investigated as a putative biomarker of multiple human cancers. However, the expression profile, epigenetic modification, prognostic value, transcription regulation, and
Externí odkaz:
https://doaj.org/article/4f0f7705c6b743d2a06ac635419aa601
Autor:
Yanlin Liu, Wenqiong Ma, Ping Zhou, Qian Wen, Qinglian Wen, Yun Lu, Ling Zhao, Huan Shi, Jie Dai, Jianmei Li, Shaozhi Fu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 160, Iss , Pp 114380- (2023)
Chemotherapy is one of the main therapeutic strategies for the treatment of malignant melanoma. Conventional chemotherapeutic agents often lack targeting abilities, and efficacy is hampered by their high toxic effects to normal tissues and rapid clea
Externí odkaz:
https://doaj.org/article/580b0a8c591243be82c8783b14914bb6
Bacteria-driven hypoxia targeting delivery of chemotherapeutic drug proving outcome of breast cancer
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Local hypoxia is a common feature of many solid tumors and may lead to unsatisfactory chemotherapy outcomes. Anaerobic bacteria that have an affinity to hypoxic areas can be used to achieve targeted drug delivery in tumor tissues. In this st
Externí odkaz:
https://doaj.org/article/511e824dcfb74c8fb655dd9dfaf34635
Autor:
Shan Tang, Yan Zhang, Yunfei Li, Yuke Xu, Haoyuan Ding, Yue Chen, Peirong Ren, Hua Ye, Shaozhi Fu, Sheng Lin
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
PurposeThis retrospective study aimed to investigate 18F-fluorodeoxyglucose (18F-FDG)-positron emission tomography/computed tomography (PET/CT) as a predictor of response to hypofractionated radiotherapy (HFRT) combined with programmed cell death-1 (
Externí odkaz:
https://doaj.org/article/973d5224f3b54fd69c8a4a3c64fa638c
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-19 (2021)
Abstract Recent insights into the molecular and cellular mechanisms underlying cancer development have revealed the tumor microenvironment (TME) immune cells to functionally affect the development and progression of breast cancer. However, insufficie
Externí odkaz:
https://doaj.org/article/cf23633f4f674f6ea94e10cb3de117a5