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Akademický článek

Cross-Omics Analyses Reveal the Effects of Ambient PM2.5 Exposure on Hepatic Metabolism in Female Mice

Autor: Ruifeng Yan, Shaoyang Ji, Tingting Ku, Nan Sang

Publikováno v: Toxics, Vol 12, Iss 8, p 587 (2024)

Ambient particulate matter (PM2.5) is a potential risk factor for metabolic damage to the liver. Epidemiological studies suggest that elevated PM2.5 concentrations cause changes in hepatic metabolism, but there is a lack of laboratory evidence. Here,

Externí odkaz: https://doaj.org/article/e347426a45004d0b991ccbb3e7da4ed4

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Akademický článek

The unique interplay of mitochondrial oxidative phosphorylation (OXPHOS) and immunity and its potential implication for the sex‐ and age‐related morbidity of severe COVID‐19 patients

Autor: Yinchuan Li, Lei Li, Guanghao Wu, Gangcai Xie, Lirong Yi, Jie Zhu, ShiYu Liang, Ya‐ru Huang, Juan Chen, Shaoyang Ji, Fei Sun, Rui‐tian Liu

Publikováno v: MedComm, Vol 4, Iss 5, Pp n/a-n/a (2023)

Abstract Aged male patients are more vulnerable to severe or critical symptoms of COVID‐19, but the underlying mechanism remains elusive. In this study, we analyzed previously published scRNA‐seq data from a large cohort of COVID‐19 patients, c

Externí odkaz: https://doaj.org/article/bc60874592334979887655ac7b59b49f

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Akademický článek

NAMPT encapsulated by extracellular vesicles from young adipose-derived mesenchymal stem cells treated tendinopathy in a 'One-Stone-Two-Birds' manner

Autor: Guanghao Wu, Qihang Su, Jie Li, Chao Xue, Jie Zhu, Qiuchen Cai, Jingbiao Huang, Shaoyang Ji, Biao Cheng, Hengan Ge

Publikováno v: Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-20 (2023)

Abstract Background Tendinopathy is the leading sports-related injury and will cause severe weakness and tenderness. Effective therapy for tendinopathy remains limited, and extracellular vesicles (EVs) derived from adipose tissue-derived mesenchymal

Externí odkaz: https://doaj.org/article/e2344269869e45c69d47b64c32e2bd85

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