Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Shaoxun Wang"'
Autor:
Xue Li, Quan Jiang, Guiyu Song, Mahsa Nouri Barkestani, Qianxun Wang, Shaoxun Wang, Matthew Fan, Caodi Fang, Bo Jiang, Justin Johnson, Arnar Geirsson, George Tellides, Jordan S. Pober, Dan Jane-wit
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Internalization of complement membrane attack complexes (MACs) assembles NLRP3 inflammasomes in endothelial cells (EC) and promotes IL-β-mediated tissue inflammation. Informed by proteomics analyses of FACS-sorted inflammasomes, we identify
Externí odkaz:
https://doaj.org/article/73d4be8bbed044429f60bcc1d5d0dca6
Autor:
Shaoxun Wang, Guiyu Song, Mahsa Nouri Barkestani, Zuzana Tobiasova, Qianxun Wang, Quan Jiang, Roberto Lopez, Yasmin Adelekan-Kamara, Matthew Fan, Jordan S. Pober, George Tellides, Dan Jane-wit
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionIschemia reperfusion injury (IRI) confers worsened outcomes and is an increasing clinical problem in solid organ transplantation. Previously, we identified a “PtchHi” T-cell subset that selectively received costimulatory signals from
Externí odkaz:
https://doaj.org/article/4ca01d1d88114534882289e450ed8b40
Autor:
Xue Li, Quan Jiang, Guiyu Song, Mahsa Nouri Barkestani, Qianxun Wang, Shaoxun Wang, Matthew Fan, Caodi Fang, Bo Jiang, Justin Johnson, Arnar Geirsson, George Tellides, Jordan S. Pober, Dan Jane-wit
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/787081c29d7e4b8bb572acf783f37322
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
Although the causes of cognitive impairment are multifactorial, emerging evidence indicates that cerebrovascular dysfunction plays an essential role in dementia. One of the most critical aspects of cerebrovascular dysfunction is autoregulation of cer
Externí odkaz:
https://doaj.org/article/bef8919a9b214ddbbdc65b9a4ecda7a2
Autor:
Guiyu Song, Shaoxun Wang, Mahsa Nouri Barkestani, Clancy Mullan, Matthew Fan, Bo Jiang, Quan Jiang, Xue Li, Dan Jane-wit
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Endothelial cells (ECs) form a critical immune interface regulating both the activation and trafficking of alloreactive T cells. In the setting of solid organ transplantation, donor-derived ECs represent sites where alloreactive T cells encounter maj
Externí odkaz:
https://doaj.org/article/51ee28ec69b04556a16ba58a7581c2e1
Autor:
Huawei Zhang, Chao Zhang, Yedan Liu, Wenjun Gao, Shaoxun Wang, Xing Fang, Ya Guo, Man Li, Ruen Liu, Richard J. Roman, Peng Sun, Fan Fan
Publikováno v:
Physiological Reports, Vol 8, Iss 2, Pp n/a-n/a (2020)
Abstract We recently reported that KO of Dual‐specificity protein phosphatase 5 (Dusp5) enhances myogenic reactivity and blood flow autoregulation in the cerebral and renal circulations in association with increased levels of pPKC and pERK1/2 in th
Externí odkaz:
https://doaj.org/article/9f34c41df2414f319e7936b45ad178f9
Autor:
Letao Fan, Shaoxun Wang, Xiaochen He, Ezekiel Gonzalez‐Fernandez, Claude Lechene, Fan Fan, Richard J. Roman
Publikováno v:
Physiological Reports, Vol 7, Iss 8, Pp n/a-n/a (2019)
Abstract This study describes a modified technique to fill the renal vasculature with a silicon rubber (Microfil) compound and obtain morphologic information about the intrarenal distribution of capillary blood flow under a variety of conditions. Kid
Externí odkaz:
https://doaj.org/article/2f21f99aa78246ff8039ae69afcdac78
Autor:
Lawrence Huang, Feng Cheng, Xuetao Zhang, Jacek Zielonka, Matthew A. Nystoriak, Weiwei Xiang, Kunal Raygor, Shaoxun Wang, Aditya Lakshmanan, Weiya Jiang, Sai Yuan, Kevin S. Hou, Jiayi Zhang, Xitao Wang, Arsalan U. Syed, Matea Juric, Takamune Takahashi, Manuel F. Navedo, Rong A. Wang
Publikováno v:
Science advances, vol 9, iss 21
Mechanisms underlying arteriovenous malformations (AVMs) are poorly understood. Using mice with endothelial cell (EC) expression of constitutively active Notch4 (Notch4* EC ), we show decreased arteriolar tone in vivo during brain AVM initiation. Red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::739e8cfdac82aba13118a0755b8d7fd5
https://escholarship.org/uc/item/4dn6d0gq
https://escholarship.org/uc/item/4dn6d0gq
Autor:
Shaoxun Wang, Guiyu Song, Barkestani, Mahsa Nouri, Zuzana Tobiasova, Qianxun Wang, Quan Jiang, Lopez, Roberto, Adelekan-Kamara, Yasmin, Fan, Matthew, Pober, Jordan S., Tellides, George, Jane-wit, Dan
Publikováno v:
Frontiers in Immunology; 2023, p1-15, 15p
Autor:
Wenjun Gao, Ezekiel Gonzalez-Fernandez, Kirby N Thomas, Fan Fan, Letao Fan, Yedan Liu, Shaoxun Wang, Richard J. Roman
Publikováno v:
Physiol Genomics
Hypertension is a leading risk factor for stroke, heart disease, chronic kidney disease, vascular cognitive impairment, and Alzheimer’s disease. Previous genetic studies have nominated hundreds of genes linked to hypertension, and renal and cogniti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca54f28ea94e8af9bd813dcfb0d5627
https://doi.org/10.1152/physiolgenomics.00119.2021
https://doi.org/10.1152/physiolgenomics.00119.2021