Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Shaoxing Zhu"'
Autor:
Nanhui Chen, Zengjun Wang, Ming Chen, Qi Ma, Yi He, Yujie Wang, Xin Li, Mingxing Qiu, Lei Shi, Shaoxing Zhu, Qun Xie, Xiuheng Liu, Benkang Shi, Guowen Lin, Weizhong Yang, Yongbin Liao, Haibin Zhang, Shusheng Wang, Jiexian Li, Shaogang Wang, Lijun Dong, Hui Chen, Jiaju Lu, Yongyi Cheng, Xiaoping Zhang, Lulin Ma, Liqun Zhou, He Wang, Shen Li, Dingwei Ye
Publikováno v:
Cancer Biology & Medicine, Vol 20, Iss 12, Pp 1047-1059 (2023)
Objective: Real-word data on long-acting luteinizing hormone-releasing hormone (LHRH) agonists in Chinese patients with prostate cancer are limited. This study aimed to determine the real-world effectiveness and safety of the LHRH agonist, goserelin,
Externí odkaz:
https://doaj.org/article/740ba6f7e2c940af8ffebb36db2754d7
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Renal cell carcinoma (RCC) is a common urologic disease. Currently, surgery is the primary treatment for renal cancer; immunotherapy is not as effective a treatment strategy as expected. Hence, understanding the mechanism in the tumor immune microenv
Externí odkaz:
https://doaj.org/article/46a7763435bd469f95654c0cec302ffc
Autor:
Xiaojian Qin, Dongmei Ji, Weijie Gu, Weiqing Han, Hong Luo, Chuanjun Du, Qing Zou, Zhongquan Sun, Chaohong He, Shaoxing Zhu, Tie Chong, Xin Yao, Ben Wan, Xinfeng Yang, Aobing Bai, Chunlei Jin, Jianjun Zou, Dingwei Ye
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background Antagonizing the androgen-receptor (AR) pathway is an effective treatment strategy for patients with metastatic castration-resistant prostate cancer (CRPC). Here, we report the results of a first-in-human phase 1/2 study which ass
Externí odkaz:
https://doaj.org/article/f3e95c021c5e4e5aa2350a0e4c884c8d
Publikováno v:
World Journal of Surgical Oncology, Vol 20, Iss 1, Pp 1-8 (2022)
Abstract Objective Second primary renal cell carcinoma (2nd RCC) refers to renal cell carcinoma (RCC) diagnosed after another unrelated malignancy. This study aims to compare the clinical manifestation, pathology, treatment, and prognostic features o
Externí odkaz:
https://doaj.org/article/752091f861b34cca9033e36b4d367ffd
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionPSMD2 plays an oncogenic role in multiple human malignancies, while it is still unclear that the potential roles and underlying mechanisms of PSMD2 in BCa.MethodsThe RNA-seq from TCGA and GTEx database was utilized to preliminarily analyz
Externí odkaz:
https://doaj.org/article/27901273fbe6419c9f9e4110d7f41089
Autor:
Zhuo Chen, Xiao Liu, Zhengjie Zhu, Jinchao Chen, Chen Wang, Xi Chen, Shaoxing Zhu, Aiqin Zhang
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Clear cell renal cell carcinoma (ccRCC) is the most common histological subtype of renal cell carcinoma (RCC). Anoikis plays an essential function in tumourigenesis, whereas the role of anoikis in ccRCC remains unclear.Methods: Anoikis-re
Externí odkaz:
https://doaj.org/article/11f04b0dea544ecaa1949d90d2fa2f11
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Bladder cancer (BCa) is a life-threaten disease with an increasing incidence with age, and immunotherapy has become an important treatment for BCa, while the efficiency of the immune system declines with age. It is vital to reveal the mechanisms of t
Externí odkaz:
https://doaj.org/article/0434a639873c44ff87e3065295edcd8a
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Background and ObjectivesThe adrenal gland is a common organ involved in metastasis. This study aimed to compare adrenal metastases (AMs) and adrenal benign masses (ABMs) of patients with extra-adrenal malignancies during the staging or follow-up.Met
Externí odkaz:
https://doaj.org/article/0ca99989866f4467a84788b7dac80806
IC50: an unsuitable measure for large-sized prostate cancer spheroids in drug sensitivity evaluation
Autor:
Yipeng Xu, Gabriela Pachnikova, He Wang, Yaoyao Wu, Dorothea Przybilla, Reinhold Schäfer, Zihao Chen, Shaoxing Zhu, Ulrich Keilholz
Publikováno v:
Biomolecules & Biomedicine, Vol 22, Iss 4 (2022)
Preclinical models of tumors have the potential to become valuable tools for commercial drug research and development, and 3D culture systems are gaining traction in this area, particularly in prostate cancer (PCa) research. However, nearly all 3D dr
Externí odkaz:
https://doaj.org/article/55af9b551abd4e14a0e501ec883fd077
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
ObjectivesTo evaluate the nature, diagnosis, treatment and prognosis of second primary renal cell carcinoma (SPRCC).Materials and MethodsWe retrospectively collected data from 118 patients with SPRCC. Clinical characteristics, imaging features and tr
Externí odkaz:
https://doaj.org/article/fdf83679149148ff82807d124f3c21b0