Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Shaosen Zhang"'
Autor:
Shaosen Zhang, Xinyi Xiao, Yonglin Yi, Xinyu Wang, Lingxuan Zhu, Yanrong Shen, Dongxin Lin, Chen Wu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-36 (2024)
Abstract Tumorigenesis is a multistep process, with oncogenic mutations in a normal cell conferring clonal advantage as the initial event. However, despite pervasive somatic mutations and clonal expansion in normal tissues, their transformation into
Externí odkaz:
https://doaj.org/article/c3fcb517b58a460d9ed4c86c501c3b87
Autor:
Peicong Ge, Zihan Yin, Chuming Tao, Chaofan Zeng, Xiaofan Yu, Shixiong Lei, Junsheng Li, Yuanren Zhai, Long Ma, Qiheng He, Chenglong Liu, Wei Liu, Bojian Zhang, Zhiyao Zheng, Siqi Mou, Zhikang Zhao, Shuang Wang, Wei Sun, Min Guo, Shuai Zheng, Jia Zhang, Xiaofeng Deng, Xingju Liu, Xun Ye, Qian Zhang, Rong Wang, Yan Zhang, Shaosen Zhang, Chengjun Wang, Ziwen Yang, Nijia Zhang, Mingxing Wu, Jian Sun, Yujia Zhou, Zhiyong Shi, Yonggang Ma, Jianpo Zhou, Shaochen Yu, Jiaxi Li, Junli Lu, Faliang Gao, Wenjing Wang, Yanming Chen, Xingen Zhu, Dong Zhang, Jizong Zhao
Publikováno v:
Chinese Neurosurgical Journal, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Background Moyamoya disease (MMD) is a rare and complex cerebrovascular disorder characterized by the progressive narrowing of the internal carotid arteries and the formation of compensatory collateral vessels. The etiology of MMD remains en
Externí odkaz:
https://doaj.org/article/b89e7299a03f4992888ba38e5512f4a9
Publikováno v:
STAR Protocols, Vol 5, Iss 4, Pp 103316- (2024)
Summary: Multiple sampling strategies to cover different or dynamic stages of malignant continuum with organoid cultures provide a valuable platform for epithelium homeostasis, transformation, and cancer progression. Here, we present a protocol to in
Externí odkaz:
https://doaj.org/article/1550859cd643477189f1fb0539394b50
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-20 (2023)
Abstract Hepatic mitochondrial dysfunction contributes to the progression of nonalcoholic fatty liver disease (NAFLD). However, the factors that maintain mitochondrial homeostasis, especially in hepatocytes, are largely unknown. Hepatocytes synthesiz
Externí odkaz:
https://doaj.org/article/d7f4d433397a483ebfadab467dda674f
Autor:
Xinyu Yang, Xinjie Chen, Shaosen Zhang, Wenyi Fan, Ce Zhong, Tianyuan Liu, Guoyu Cheng, Liang Zhu, Qingyi Liu, Yiyi Xi, Wen Tan, Dongxin Lin, Chen Wu
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113270- (2023)
Summary: Esophageal squamous-cell carcinoma (ESCC) is commonly treated with radiotherapy; however, radioresistance hinders its clinical effectiveness, and the underlying mechanism remains elusive. Here, we develop patient-derived xenografts (PDXs) fr
Externí odkaz:
https://doaj.org/article/d04156876e2748fdb04c7362e6f83f66
Autor:
Shaosen Zhang, Shengjun Sun, Yuanren Zhai, Xiaochen Wang, Qian Zhang, Zhiyong Shi, Peicong Ge, Dong Zhang
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/3059406716ab429392b6ad153fa6832b
Autor:
Shaosen Zhang, Shengjun Sun, Yuanren Zhai, Xiaochen Wang, Qian Zhang, Zhiyong Shi, Peicong Ge, Dong Zhang
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
ObjectiveBrain arteriovenous malformation (bAVM) is an important reason for intracranial hemorrhage. This study aimed at developing and validating a model for predicting bAVMs rupture by using three-dimensional (3D) morphological features extracted f
Externí odkaz:
https://doaj.org/article/95bfeb157fa246698a19cf6ffcb2a3e1
Autor:
Xiannian Zhang, Linna Peng, Yingying Luo, Shaosen Zhang, Yang Pu, Yamei Chen, Wenjia Guo, Jiacheng Yao, Mingming Shao, Wenyi Fan, Qionghua Cui, Yiyi Xi, Yanxia Sun, Xiangjie Niu, Xuan Zhao, Liping Chen, Yuqian Wang, Yachen Liu, Xinyu Yang, Chengcheng Wang, Ce Zhong, Wen Tan, Jianbin Wang, Chen Wu, Dongxin Lin
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Esophageal squamous-cell carcinomas (ESCC) have poor prognosis, and detailed molecular profiles are necessary to identify prognostic markers. Here the authors analyse 60 ESCC patient samples using scRNA-seq, TCR-seq and genomics; they find mucosal im
Externí odkaz:
https://doaj.org/article/966baaf37bd24053a182f83c179aec72
Autor:
Weiling Liu, Chuanwang Miao, Shaosen Zhang, Yachen Liu, Xiangjie Niu, Yiyi Xi, Wenjia Guo, Jiahui Chu, Ai Lin, Hongjin Liu, Xinyu Yang, Xinjie Chen, Ce Zhong, Yuling Ma, Yuqian Wang, Shihao Zhu, Shuning Liu, Wen Tan, Dongxin Lin, Chen Wu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-14 (2021)
Abstract Radiotherapy remains the mainstay for treatment of various types of human cancer; however, the clinical efficacy is often limited by radioresistance, in which the underlying mechanism is largely unknown. Here, using esophageal squamous cell
Externí odkaz:
https://doaj.org/article/6d320b61d42248d7b7ad6a2cdbb98293
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Tumor-secreted proteins can provide numerous molecular targets for cancer diagnosis and treatment. Of note, pyruvate kinase M2 (PKM2) is secreted by tumor cells to promote malignant progression, while its regulatory mechanism or the interacting netwo
Externí odkaz:
https://doaj.org/article/ad31ba94d92049dfa7537414566f4a92