Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Shaoqiu Leng"'
Autor:
Xiaoyu Zhang, Shaoqiu Leng, Xinyue Liu, Xiang Hu, Yan Liu, Xin Li, Qi Feng, Wei Guo, Nailin Li, Zi Sheng, Shuwen Wang, Jun Peng
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-19 (2024)
Abstract Background Vasculopathy is the most common complication of diabetes. Endothelial cells located in the innermost layer of blood vessels are constantly affected by blood flow or vascular components; thus, their mechanosensitivity plays an impo
Externí odkaz:
https://doaj.org/article/2e99eb2cf36c43809ace2f5cee130523
Autor:
Yan Liu, Xinyi Zuo, Peng Chen, Xiang Hu, Zi Sheng, Anli Liu, Qiang Liu, Shaoqiu Leng, Xiaoyu Zhang, Xin Li, Limei Wang, Qi Feng, Chaoyang Li, Ming Hou, Chong Chu, Shihui Ma, Shuwen Wang, Jun Peng
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-18 (2022)
Abstract Immune thrombocytopenia (ITP) is an autoimmune disorder, in which megakaryocyte dysfunction caused by an autoimmune reaction can lead to thrombocytopenia, although the underlying mechanisms remain unclear. Here, we performed single-cell tran
Externí odkaz:
https://doaj.org/article/24c622ba58554496b1e245eae3efbfe5
Autor:
Shaoqiu Leng, Xiaoyu Zhang, Shuwen Wang, Jing Qin, Qiang Liu, Anli Liu, Zi Sheng, Qi Feng, Xiang Hu, Jun Peng
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Altered microenvironmental stiffness is a hallmark of inflammation. It is sensed by the mechanically activated cation channel Piezo1 in macrophages to induce subsequent immune responses. However, the mechanism by which the mechanosensitive signals sh
Externí odkaz:
https://doaj.org/article/75911c6b192e4eafa0718dc9f4783e0a
Autor:
Shuwen Wang, Xiaoyu Zhang, Shaoqiu Leng, Qirui Xu, Zi Sheng, Yanqi Zhang, Jie Yu, Qi Feng, Ming Hou, Jun Peng, Xiang Hu
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Cancer immunotherapy by immune checkpoint blockade has been effective in the treatment of certain tumors. However, the association between immune checkpoints and autoimmune diseases remains elusive and requires urgent investigation. Primary immune th
Externí odkaz:
https://doaj.org/article/90a45ee8403642b182a4717f402301e0
Publikováno v:
Clinical and Experimental Immunology. 211:68-77
Common variable immunodeficiency (CVID) is a ‘late-onset’ primary immunodeficiency characterized by variable manifestations and genetic heterogeneity. A monogenic cause of CVID has been reported in 10% of patients. In this study, we identified tw
Autor:
Jing Qin, Qiang Liu, Anli Liu, Shaoqiu Leng, Shuwen Wang, Chaoyang Li, Ji Ma, Jun Peng, Miao Xu
Publikováno v:
British Journal of Haematology. 198:765-775
Autor:
Yu Hou, Jie Xie, Shuwen Wang, Daqi Li, Lingjun Wang, Haoyi Wang, Xiaofei Ni, Shaoqiu Leng, Guosheng Li, Ming Hou, Jun Peng
Publikováno v:
Cell Mol Immunol
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature cells and natural inhibitors of adaptive immunity. Intracellular metabolic changes in MDSCs exert a direct immunological influence on their suppressive activity. Our
Lineage Tracing Reveals the Dynamic Contribution of Id2+ Progenitor Cells to Branching Morphogenesis
Publikováno v:
Stem Cells and Development. 31:67-77
Autor:
Nan Jiang, Yin Wang, Qi Feng, Shuwen Wang, Shaoqiu Leng, Xiaoyu Zhang, Qiang Liu, Jun Peng, Xin Li
Publikováno v:
International Journal of Laboratory Hematology.
Autor:
Xiaoyu Zhang, Zeping Zhou, Jun Peng, Shuwen Wang, Shaoqiu Leng, Yanqi Zhang, Ju Li, Qi Feng, Xiang Hu
Publikováno v:
Annals of Hematology. 100:2453-2462
Primary immune thrombocytopenia (ITP) is an autoimmune disorder characterized by decreased platelet count. While corticosteroids are a useful first-line therapy for ITP patients, their long-term effectiveness is limited, and the determinants of corti