Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Shaoping Sun"'
Autor:
Jia Chen, Hong Li, Sicheng Guo, Zhe Yang, Shaoping Sun, JunJie Zeng, Hongjuan Gou, Yechang Chen, Feng Wang, Yanping Lin, Kun Huang, Hong Yue, Yuting Ma, Yubi Lin
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-14 (2022)
Abstract Background Brugada syndrome (Brs) and long QT syndrome (LQTs) are the most observed “inherited primary arrhythmia syndromes” and “channelopathies”, which lead to sudden cardiac death. Methods Detailed clinical information of Brs and
Externí odkaz:
https://doaj.org/article/9a89172c6457447ba1f5f31015588ffe
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Autism spectrum disorder (ASD) is a class of neurodevelopmental disorders characterized by genetic and environmental risk factors. The pathogenesis of ASD has a strong genetic basis, consisting of rare de novo or inherited variants among a variety of
Externí odkaz:
https://doaj.org/article/8b4a6c2a1a72421188deff2b307a5309
Publikováno v:
Polymers, Vol 12, Iss 2, p 380 (2020)
In this study, a redox-sensitive chitosan derivative with modifications by cholesterol, sulfhydryl, and mPEG (mPEG-CS(SH)-CHO) was successfully synthesized and characterized. Due to its amphiphilicity, the conjugate could spontaneously form micelles
Externí odkaz:
https://doaj.org/article/6593e3d99f434041ac15ce4872ed02b4
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 54, Iss 2 (2018)
ABSTRACT The aim of the present study was to characterize biotin-decorated docetaxel-loaded bovine serum albumin nanoparticles (DTX-BIO-BSA-NPs) and evaluate their antiproliferative activity in vitro. The particle size of prepared DTX-BIO-BSA-NPs was
Externí odkaz:
https://doaj.org/article/62abd59bce9a4268a8c7e5e6fa3a747d
Publikováno v:
Biomacromolecules. 24:178-189
In this study, a tumor-targeting and pH-sensitive inclusion complex based on the host-guest recognition between the chitosan and folic acid grafted HP-β-CD (FA-CS-CD) and stearic acid modified 2-benzimidazolemethanol (BM-SA) was designed and fabrica
Publikováno v:
Journal of Drug Delivery Science and Technology. 84:104538
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 18; Pages: 10801
In the present study, an amphiphilic polymer was prepared by conjugating methoxy poly(ethylene glycol) (mPEG) with tetraphenylethene (TPE) via disulfide bonds (Bi(mPEG-S-S)-TPE). The polymer could self-assemble into micelles and solubilize hydrophobi
Publikováno v:
European Polymer Journal. 189:111974
Publikováno v:
Pharmaceutical Chemistry Journal. 53:624-627
The cytotoxic activity of twenty three new biphenyl compounds was investigated, and the IC50 value of 1,2-dinitrodibenzo [b,d]oxepin-7(6H)-one (DNDBO) was found to be the lowest among these compounds. The underlying mechanism of DNDBO-induced cell de
Publikováno v:
Carbohydrate Polymers. 216:129-139
A novel biotin and arginine modified hydroxypropyl-β-cyclodextrin (biotin-Arg(pbf)-HP-β-CD) was successfully synthesized. The hydroxyl groups of HP-β-CD on the primary faces were coupled with carboxyl groups of biotin using arginine as the functio