Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Shaon Chakrabarti"'
Autor:
Archit Singh, Shaon Chakrabarti
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 12, p e1011725 (2023)
The dynamics of inheritance of histones and their associated modifications across cell divisions can have major consequences on maintenance of the cellular epigenomic state. Recent experiments contradict the long-held notion that histone inheritance
Externí odkaz:
https://doaj.org/article/752f002d03994dc49f1dcaa3c4069649
Autor:
Sangeeta Chawla, John O’Neill, Marina I. Knight, Yuqing He, Lei Wang, Erik Maronde, Sergio Gil Rodríguez, Gerben van Ooijen, Eduardo Garbarino-Pico, Eva Wolf, Ouria Dkhissi-Benyahya, Anjoom Nikhat, Shaon Chakrabarti, Shawn D. Youngstedt, Natalie Zi-Ching Mak, Ignacio Provencio, Henrik Oster, Namni Goel, Mario Caba, Maria Oosthuizen, Giles E. Duffield, Christopher Chabot, Seth J. Davis
Publikováno v:
Journal of Circadian Rhythms, Vol 22, Pp 2-2 (2024)
Chronobiology investigations have revealed much about cellular and physiological clockworks but we are far from having a complete mechanistic understanding of the physiological and ecological implications. Here we present some unresolved questions in
Externí odkaz:
https://doaj.org/article/db502127013240719d08119a18f1cd60
Autor:
Sangeeta Chawla, Henrik Oster, Giles E. Duffield, Erik Maronde, Mario E. Guido, Christopher Chabot, Ouria Dkhissi-Benyahya, Ignacio Provencio, Namni Goel, Shawn D. Youngstedt, Natalie Zi-Ching Mak, Mario Caba, Anjoom Nikhat, Shaon Chakrabarti, Lei Wang, Seth J. Davis
Publikováno v:
Journal of Circadian Rhythms, Vol 22, Pp 1-1 (2024)
Circadian Biology intersects with diverse scientific domains, intricately woven into the fabric of organismal physiology and behavior. The rhythmic orchestration of life by the circadian clock serves as a focal point for researchers across discipline
Externí odkaz:
https://doaj.org/article/a575223ac92d449cb7db174dcd3aca01
Autor:
Kamrine E. Poels, Adam J. Schoenfeld, Alex Makhnin, Yosef Tobi, Yuli Wang, Heidie Frisco-Cabanos, Shaon Chakrabarti, Manli Shi, Chelsi Napoli, Thomas O. McDonald, Weiwei Tan, Aaron Hata, Scott L. Weinrich, Helena A. Yu, Franziska Michor
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Osimertinib and dacomitinib are approved as first-line treatment of EGFR-mutant NSCLC but resistance can arise. Here, the authors use a computational model to identify an optimal dosing schedule for osimertinib and dacomitinib combination therapy tha
Externí odkaz:
https://doaj.org/article/f560d9720b2540fab5539f7d8afa3e27
Autor:
Kamrine E. Poels, Adam J. Schoenfeld, Alex Makhnin, Yosef Tobi, Yuli Wang, Heidie Frisco-Cabanos, Shaon Chakrabarti, Manli Shi, Chelsi Napoli, Thomas O. McDonald, Weiwei Tan, Aaron Hata, Scott L. Weinrich, Helena A. Yu, Franziska Michor
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/0d2dddae1cc34582bd3de123927fce55
Autor:
Shaon Chakrabarti, Andrew L. Paek, Jose Reyes, Kathleen A. Lasick, Galit Lahav, Franziska Michor
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
The origins of lineage correlations and heterogeneity in division and apoptosis times among single cells are incompletely understood. Here, a new lineage tracking data analysis approach reveals that circadian oscillations may underlie cell fate contr
Externí odkaz:
https://doaj.org/article/01e9efd3bfb140d087a5b3c73a4ee514
Autor:
Franziska Michor, Shaon Chakrabarti
Supplemental data for the main manuscript. Contains derivations of main formulae used in text, analysis of different dosing schedules, estimation of parameters for the TATTON trial and discussions regarding assumptions made in the analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92af3df7ae66c79e321f396e56d2ea38
https://doi.org/10.1158/0008-5472.22415355
https://doi.org/10.1158/0008-5472.22415355
Autor:
Franziska Michor, Shaon Chakrabarti
The identification of optimal drug administration schedules to battle the emergence of resistance is a major challenge in cancer research. The existence of a multitude of resistance mechanisms necessitates administering drugs in combination, signific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6443b6f6c2042b231bae9d6d7cbb405
https://doi.org/10.1158/0008-5472.c.6509247.v1
https://doi.org/10.1158/0008-5472.c.6509247.v1
Publikováno v:
bioRxiv
Detecting oscillations in time series remains a challenging problem even after decades of research. In chronobiology, rhythms in time series (for instance gene expression, eclosion, egg-laying and feeding) datasets tend to be low amplitude, display l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82100c1b09b3a0a0ffb3e271b2a41cc7
https://europepmc.org/articles/PMC10055182/
https://europepmc.org/articles/PMC10055182/
Autor:
Archit Singh, Shaon Chakrabarti
The dynamics of inheritance of histones and their associated modifications across cell divisions can have major consequences on maintenance of the cellular epigenomic state. Recent experiments contradict the long-held notion that histone inheritance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::037faf30f07fde16d80bb9eef45abdd8
https://doi.org/10.1101/2022.08.31.505992
https://doi.org/10.1101/2022.08.31.505992