Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shaomin Qian"'
Autor:
Julie A. Mund, Xiaohong Li, Abbi Smith, George E. Sandusky, Qingbo Lu, Shaomin Qian, Waylan K. Bessler, Andrew E. Horvai, William Dyer, Steven D. Rhodes, Yongzheng He, Amy E. Armstrong, D. Wade Clapp, Li Jiang
Publikováno v:
Hum Mol Genet
Plexiform neurofibroma (PN) tumors are a hallmark manifestation of neurofibromatosis type 1 (NF1) that arise in the Schwann cell (SC) lineage. NF1 is a common heritable cancer predisposition syndrome caused by germline mutations in the NF1 tumor supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd27dafef94c9892a5195f8cf0110e81
https://doi.org/10.1093/hmg/ddz095
https://doi.org/10.1093/hmg/ddz095
Autor:
Jenna N. Regan, April M. Hoggatt, Cheikh I. Seye, Maxwell T. Shelton, Paul Herring, Khalid S. Mohammad, Shaomin Qian
Publikováno v:
Atherosclerosis. 257:38-46
Background and aims Mutations in the 5'-nucleotidase ecto (NT5E) gene that encodes CD73, a nucleotidase that converts AMP to adenosine, are linked to arterial calcification. However, the role of purinergic receptor signaling in the pathology of intim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0462cf480861f99e269fb890b3372a91
Autor:
Yava L. Jones-Hall, April M. Hoggatt, Shaomin Qian, Paul Herring, Carl F. Ware, Cheikh I. Seye
Publikováno v:
Vascular pharmacology
Background Lymphotoxin alpha (LTα) is expressed in human atherosclerotic lesions and genetic variations in the LTα pathway have been linked to myocardial infarction. Activation of the P2Y2 nucleotide receptor (P2Y2R) regulates the production of LT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd90a9c65d53f6354ba2ac79f49d327
Publikováno v:
Journal of Vascular Research. 53:163-171
Objectives: Extracellular nucleotide release at the site of arterial injury mediates the proliferation and migration of vascular smooth muscle cells. Our aim was to investigate the role of the P2Y2 nucleotide receptor (P2Y2R) in neointimal hyperplasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25a36da1826c1f0ef2f802a7f9e94634
https://doi.org/10.1159/000449059
https://doi.org/10.1159/000449059
Autor:
Shaomin Qian, Cheikh I. Seye, Alexander G. Obukhov, April M. Hoggatt, Timothy A. Hacker, Paul Herring, Hongying Tang, Xingjuan Chen
Objective— Nucleotide P2Y 2 receptor (P2Y 2 R) contributes to vascular inflammation by increasing vascular cell adhesion molecule-1 expression in endothelial cells (EC), and global P2Y 2 R deficiency prevents fatty streak formation in apolipoprotei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49bdb1106ed1857f9f92cd24cc29215
https://europepmc.org/articles/PMC5268079/
https://europepmc.org/articles/PMC5268079/
Autor:
Shaomin, Qian, Jenna N, Regan, Maxwell T, Shelton, April, Hoggatt, Khalid S, Mohammad, Paul B, Herring, Cheikh I, Seye
Publikováno v:
Atherosclerosis. 257
Mutations in the 5'-nucleotidase ecto (NT5E) gene that encodes CD73, a nucleotidase that converts AMP to adenosine, are linked to arterial calcification. However, the role of purinergic receptor signaling in the pathology of intimal calcification is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::757900d20446f341dcd0b2c6aa3a6f78
https://pubmed.ncbi.nlm.nih.gov/28038380
https://pubmed.ncbi.nlm.nih.gov/28038380
Publikováno v:
Journal of vascular research. 53(3-4)
Extracellular nucleotide release at the site of arterial injury mediates the proliferation and migration of vascular smooth muscle cells. Our aim was to investigate the role of the P2Y2 nucleotide receptor (P2Y2R) in neointimal hyperplasia. Approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef65e97d1ce4b9e677991690a1d59306
https://pubmed.ncbi.nlm.nih.gov/27723650
https://pubmed.ncbi.nlm.nih.gov/27723650
Publikováno v:
Circulation Research. 117
Objective: Vascular calcification is widespread in individuals with atherosclerosis, and is associated with inflammatory changes and expression of osteoblast-like cell phenotypes. Recent studies identified extracellular nucleotides and P2Y receptor c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bc3372e287c17940ff29a6ce86cb189
https://doi.org/10.1161/res.117.suppl_1.341
https://doi.org/10.1161/res.117.suppl_1.341
Autor:
Clark E Boccone, Krishna M. Vattem, James P. Walsh, Ronald C. Wek, Ying Jiang, Takahiro Abe, Shaomin Qian, Xiaolan Lu
Publikováno v:
Biochemical Journal. 375:673-680
Diacylglycerol kinases (DAGKs) catalyse ATP-dependent phosphorylation of sn-1,2-diacylglycerol that arises during stimulated phosphatidylinositol turnover. DAGKα is activated in vitro by Ca2+ and by acidic phospholipids. The regulatory region of DAG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdaa48e2156adaa4337a3c94ad8d01ec
https://doi.org/10.1042/bj20031052
https://doi.org/10.1042/bj20031052
Publikováno v:
Circulation Research. 111
Rationale: Nucleotides acting via P2Y 2 nucleotide receptors (P2Y 2 R) regulate both migration of vascular smooth muscle cells and endothelial recruitment of monocyte/macrophage in vivo. Objective: We aimed to determine whether inactivation of the P2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c8e42ea2f80a1f36bbe6378450c2fb9
https://doi.org/10.1161/res.111.suppl_1.a343
https://doi.org/10.1161/res.111.suppl_1.a343