Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Shaokun Chen"'
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract Post‐replicative DNA N6‐methyladenine (pr6mdA) can form via bona fide methylase‐catalyzed adenine methylation, playing a pivotal role in embryonic development and other biological processes. Surprisingly, pre‐methylated adenine can b
Externí odkaz:
https://doaj.org/article/59b532f368f943f083d3cb61bacd341f
Autor:
Jinshan Xing, Xin Luo, Keran Jia, Shuang Liu, Shaokun Chen, Gan Qiao, Chunxiang Zhang, Jingyan Yi
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-11 (2023)
Abstract Background Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder in women of reproductive age that still lacks effective treatment. Inflammation is one of the important features of PCOS. Asparagus (ASP) has anti-inflam
Externí odkaz:
https://doaj.org/article/548c0ab1d841470b848758084268c491
Autor:
Cong Lyu, Yamei Niu, Weiyi Lai, Yu Wang, Yaning Wang, Peibin Dai, Chunhui Ma, Shaokun Chen, Yao Li, Guibin Jiang, Zhiyong Liang, Wenbin Ma, Zhengliang Gao, Wei-Min Tong, Hailin Wang
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-15 (2022)
Abstract The entity of DNA N6-methyladenine (6mA) in mammals remains elusive and subsequently its roles in diseases are poorly understood. Here we exploited a bacterial DNA contamination-free and ultrasensitive UHPLC-MS/MS assay to reassess DNA 6mA i
Externí odkaz:
https://doaj.org/article/9dfac327a6ab418eabca4d82c3b2024f
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Objectives: Pulmonary artery hypertension (PAH) is a serious disease for which there is no effective treatment. Its pathogenesis is complex and has not yet been clarified. Tex261 is a protein-coding gene whose functional enrichment nodes include the
Externí odkaz:
https://doaj.org/article/65bdbe44bffe4cfd857570c82398cc32
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-20 (2019)
Abstract Background Pulmonary artery hypertension (PAH), which is characterized by an increase in pulmonary circulation blood pressure, is a fatal disease, and its pathogenesis remains unclear. Methods In this study, RNA sequencing (RNA-seq), tandem
Externí odkaz:
https://doaj.org/article/53b6b6d6b3e64f518cdd99b57f34bde2
Autor:
Chunhong Feng, Kai He, Chunyan Zhang, Song Su, Bo Li, Yuxiao Li, Chun-Yan Duan, Shaokun Chen, Run Chen, Youping Liu, Hong Li, Mei Wei, Xianming Xia, Rongyang Dai
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e90388 (2014)
Less is known about the roles of c-Jun N-terminal kinase (JNK) in cholangiocarcinoma (CCA). Here, we report that JNK exerts its oncogenic action in human CCA cells, partially due to the mammalian target of rapamycin (mTOR) pathway regulated glucose-r
Externí odkaz:
https://doaj.org/article/5813ddf161e64dc7951e51c2014def5b
Autor:
Jinshan Xing, Gan Qiao, Xin Luo, Shuang Liu, Shaokun Chen, Geng Ye, Chunxiang Zhang, Jingyan Yi
Publikováno v:
Clinical Science. 137:453-468
Polycystic ovary syndrome (PCOS), a common reproductive endocrine disorder in women of reproductive age, causes anovulatory infertility. Increased apoptosis of granulosa cells has been identified as one of the key factors contributing to abnormal fol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db154d64b46569ecad0d271812bbf35f
https://doi.org/10.1042/cs20220408
https://doi.org/10.1042/cs20220408
Publikováno v:
Chemical Research in Toxicology. 35:387-391
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy that causes endless pain for patients and accounts for thousands of deaths worldwide. The development of an effective AML treatment is a topic of ongoing interest. Here, we demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb192f7216e87418b0c09e813d99c080
https://doi.org/10.1021/acs.chemrestox.2c00044
https://doi.org/10.1021/acs.chemrestox.2c00044
Publikováno v:
Acta Geologica Sinica - English Edition. 95:1065-1072
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::375870ee43a5b17f0d1672a8cfa11ed2
https://doi.org/10.1111/1755-6724.14719
https://doi.org/10.1111/1755-6724.14719
Publikováno v:
Analytical Chemistry. 93:4794-4799
Benefiting from specific target recognition by antibodies, the immunoassay is one of the widely used assays for the detection of biologically and environmentally important small molecules in broad fields. It can be challenge to isolate small molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d05cb7c19fe8cfd9a89c852e0c9ef3bd
https://doi.org/10.1021/acs.analchem.0c05386
https://doi.org/10.1021/acs.analchem.0c05386