Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Shaoguang Wu"'
Autor:
Sivaranjani Namasivayam, Curtis Tilves, Hua Ding, Shaoguang Wu, Jada C Domingue, Camilo Ruiz-Bedoya, Ankit Shah, Eric Bohrnsen, Benjamin Schwarz, Mickayla Bacorn, Qing Chen, Shira Levy, Maria Gloria Dominguez Bello, Sanjay K Jain, Cynthia L Sears, Noel T Mueller, Suchitra K Hourigan
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Exposing C-section infants to the maternal vaginal microbiome, coined “vaginal seeding”, partially restores microbial colonization. However, whether vaginal seeding decreases metabolic disease risk is unknown. Therefore, we assessed the effect of
Externí odkaz:
https://doaj.org/article/ed1023d96e4e4dfa90f0fb2d54bb814f
Autor:
Sheetal Parida, Sumit Siddharth, Himavanth R. Gatla, Shaoguang Wu, Guannan Wang, Kathleen Gabrielson, Cynthia L. Sears, Brian H. Ladle, Dipali Sharma
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionObesity, an independent risk factor for breast cancer growth and metastatic progression, is also closely intertwined with gut dysbiosis; and both obese state and dysbiosis promote each other. Enteric abundance of Bacteroides fragilis is s
Externí odkaz:
https://doaj.org/article/d5bdc0018bcb483684d115d9a90c3c90
Autor:
Annemarie Boleij, Payam Fathi, William Dalton, Ben Park, Xinqun Wu, David Huso, Jawara Allen, Sepideh Besharati, Robert A. Anders, Franck Housseau, Amanda E. Mackenzie, Laura Jenkins, Graeme. Milligan, Shaoguang Wu, Cynthia L. Sears
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Boleij et al. show that G protein-coupled receptor 35 (GPR35) regulates the responses to enterotoxigenic Bacteroides fragilis (ETBF) in colonic epithelial cells. They find that GPR35-deficiency nearly protected mice from ETBF-induced death, suggestin
Externí odkaz:
https://doaj.org/article/2986eba9551643dc8608d3a4c5b5b496
Autor:
Jawara Allen, Axel Rosendahl Huber, Cayetano Pleguezuelos-Manzano, Jens Puschhof, Shaoguang Wu, Xinqun Wu, Charelle Boot, Aurelia Saftien, Heather M. O’Hagan, Hao Wang, Ruben van Boxtel, Hans Clevers, Cynthia L. Sears
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT Enterotoxigenic Bacteroides fragilis (ETBF) is consistently found at higher frequency in individuals with sporadic and hereditary colorectal cancer (CRC) and induces tumorigenesis in several mouse models of CRC. However, whether specific mut
Externí odkaz:
https://doaj.org/article/c8b925b4810c4dcabf9cb25d68e6536b
Autor:
Jessica Queen, Jada C. Domingue, James Robert White, Courtney Stevens, Barath Udayasuryan, Tam T. D. Nguyen, Shaoguang Wu, Hua Ding, Hongni Fan, Madison McMann, Alina Corona, Tatianna C. Larman, Scott S. Verbridge, Franck Housseau, Daniel J. Slade, Julia L. Drewes, Cynthia L. Sears
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Fusobacteria are commonly associated with human colorectal cancer (CRC), but investigations are hampered by the absence of a stably colonized murine model. Further, Fusobacterium nucleatum subspecies isolated from human CRC have not been inv
Externí odkaz:
https://doaj.org/article/0a9d26e8a85f4e6d870c28b44bda70be
Autor:
Rahwa Taddese, Rian Roelofs, Derk Draper, Xinqun Wu, Shaoguang Wu, Dorine W. Swinkels, Harold Tjalsma, Annemarie Boleij
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
ObjectiveThe opportunistic pathogen Streptococcus gallolyticus is one of the few intestinal bacteria that has been consistently linked to colorectal cancer (CRC). This study aimed to identify novel S. gallolyticus-induced pathways in colon epithelial
Externí odkaz:
https://doaj.org/article/7faf83399274470ea74eb45cd450e5cf
Autor:
Laxmi Sunuwar, Azra Frkatović, Sodbo Sharapov, Qinchuan Wang, Heather M. Neu, Xinqun Wu, Talin Haritunians, Fengyi Wan, Sarah Michel, Shaoguang Wu, Mark Donowitz, Dermot McGovern, Gordan Lauc, Cynthia Sears, Joanna Melia
Publikováno v:
JCI Insight, Vol 5, Iss 20 (2020)
ZIP8 is a metal transporter with a role in manganese (Mn) homeostasis. A common genetic variant in ZIP8 (rs13107325; A391T) ranks in the top 10 of pleiotropic SNPs identified in GWAS; A391T has associations with an increased risk of schizophrenia, ob
Externí odkaz:
https://doaj.org/article/c8a8d7250ef44726afdebb8c100fb512
Autor:
Paul Metz, Martijn J. H. Tjan, Shaoguang Wu, Mehrosh Pervaiz, Susanne Hermans, Aishwarya Shettigar, Cynthia L. Sears, Tina Ritschel, Bas E. Dutilh, Annemarie Boleij
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Objective: The human intestinal microbiome plays an important role in inflammatory bowel disease (IBD) and colorectal cancer (CRC) development. One of the first discovered bacterial mediators involves Bacteroides fragilis toxin (BFT, also named as fr
Externí odkaz:
https://doaj.org/article/1225d98a62fe433b9ef8caabf065e352
Publikováno v:
ACS Sensors. 7:1495-1505
Delineating the molecular and morphological changes that cancer cells undergo in response to extracellular stimuli is crucial for identifying factors that promote tumor progression. Label-free optical imaging offers a potentially promising route for
Autor:
Cynthia L. Sears, Ken S. Lau, Franck Housseau, Robert J. Coffey, Fengyi Wan, Christian Jobin, Seth T. Walk, Robert A. Anders, Martha J. Shrubsole, Karen Carroll, Patricia Simner, Hua Ding, Shaoguang Wu, Xinqun Wu, Cody N. Heiser, Victoria L. Campodónico, Fuad Mohammad, James R. White, John Michel, Sarah Tomkovich, Christine M. Dejea, Courtney Stevens, Madison McMann, Lana Kim, June L. Chan, Ada J. Tam, Jada C. Domingue, Reece J. Knippel, Nicholas O. Markham, Jie Chen, Julia L. Drewes
Supplementary Figure from Human Colon Cancer–Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c36d44bf3f5e625f3e60e16ee8e663e
https://doi.org/10.1158/2159-8290.22541276
https://doi.org/10.1158/2159-8290.22541276