Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Shaodong Dai"'
Structural Basis of Nucleic Acid Recognition and 6mA Demethylation by Caenorhabditis elegans NMAD-1A
Autor:
Guohui Shang, Meiting Yang, Min Li, Lulu Ma, Yunlong Liu, Jun Ma, Yiyun Chen, Xue Wang, Shilong Fan, Mengjia Xie, Wei Wu, Shaodong Dai, Zhongzhou Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 686 (2024)
N6-methyladenine (6mA) of DNA is an emerging epigenetic mark in the genomes of Chlamydomonas, Caenorhabditis elegans, and mammals recently. Levels of 6mA undergo drastic fluctuation and thus affect fertility during meiosis and early embryogenesis. He
Externí odkaz:
https://doaj.org/article/8b7a77df75214cd8a59c70db9f3cdc9f
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide with critical roles in the development of peripheral sensitization and pain. One of the CGRP family peptides, islet amyloid polypeptide (IAPP), is an important autoantigen in
Externí odkaz:
https://doaj.org/article/2d94f38efa924f2ab504842e15a02f74
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Increasing evidence suggested that the islet amyloid polypeptide (IAPP) is an essential autoantigen in the pathogenesis of type 1 diabetes (T1D) in humans and non-obese diabetic (NOD) mice. A unique disulfide containing IAPP-derived peptide KS20 is o
Externí odkaz:
https://doaj.org/article/62af46cb4f1049809eaf22a21eee7045
Autor:
Yang Wang, Alexandra Tsitsiklis, Stephanie Devoe, Wei Gao, H. Hamlet Chu, Yan Zhang, Wei Li, Wing Ki Wong, Charlotte M. Deane, David Neau, Jill E. Slansky, Paul G. Thomas, Ellen A. Robey, Shaodong Dai
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Certain CD8 T cell responses are particularly effective at controlling infection, as exemplified by elite control of HIV in individuals harboring HLA-B57. To understand the structural features that contribute to CD8 T cell elite control, we focused o
Externí odkaz:
https://doaj.org/article/7ffa5a501e02421090f8abaab1877c09
Autor:
Alexandra Tsitsiklis, Derek J. Bangs, Lydia K. Lutes, Shiao W. Chan, Kristina M. Geiger, Andrew J. Modzelewski, Lara Labarta-Bajo, Yang Wang, Elina I. Zuniga, Shaodong Dai, Ellen A. Robey
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The CD8+ T cell response to the intracellular parasite Toxoplasma gondii varies dramatically between mouse strains, resulting in stark differences in control of the parasite. Protection in BALB/c mice can be attributed to an unusually strong and prot
Externí odkaz:
https://doaj.org/article/4aa56ee319d5430d9240f09b8b10ac7c
Autor:
Joseph Ray Cepeda, Nitin S Sekhar, Junying Han, Wei Xiong, Ningyan Zhang, Liping Yu, Shaodong Dai, Howard W. Davidson, John W. Kappler, Zhiqiang An, Li Zhang
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Activation of T cells specific for insulin B chain amino acids 9 to 23 (B:9–23) is essential for the initiation of type 1 diabetes (T1D) in non-obese diabetic mice. We previously reported that peptide/MHC complexes containing optimized B:9–23 mim
Externí odkaz:
https://doaj.org/article/72ce24d0357c4b38886ed579e0584dd3
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2428 (2021)
Nickel (Ni2+) is one of the most common allergens, affecting around 10–15% of the general population. As the demand for orthopedic implant surgery rises, the number of surgical revisions due to joint implant failure also increases. There is evidenc
Externí odkaz:
https://doaj.org/article/0eaff64eaaf6496c81fcf3a934a2d40c
Autor:
Hanmant Gaikwad, Yue Li, Guankui Wang, Ronghui Li, Shaodong Dai, Cody Rester, Ross Kedl, Laura Saba, Nirmal K. Banda, Robert I. Scheinman, Casey Patrick, Krishna M.G. Mallela, S. Moein Moghimi, Dmitri Simberg
Publikováno v:
ACS Nano. 16:8704-8715
Many aspects of innate immune responses to SARS viruses remain unclear. Of particular interest is the role of emerging neutralizing antibodies against the receptor-binding domain (RBD) of SARS-CoV-2 in complement activation and opsonization. To overc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075a84763c8326e5b06d80f760396cc6
https://doi.org/10.1021/acsnano.2c02794
https://doi.org/10.1021/acsnano.2c02794
Autor:
Wei Ye, Wei Wu, Shaodong Dai, Zhongzhou Chen, Hong-Wei Wang, Manfeng Zhang, Hongyun Lu, Jia Wang, Xue Wang, Cuixia Hu, Jie Xu, Xiaofei Dong, Fanglin Zhang, Xiaorong Li
Publikováno v:
J Virol
Rift Valley fever virus (RVFV) belongs to the order Bunyavirales and is the type species of genus Phlebovirus, which accounts for over 50% of family Phenuiviridae species. RVFV is mosquito-borne and causes severe diseases in both humans and livestock
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::585b88f36325dc6852d8aad8322432b8
https://doi.org/10.1128/jvi.01713-21
https://doi.org/10.1128/jvi.01713-21
Autor:
John W. Kappler, Jill E. Slansky, Philippa Marrack, Shaodong Dai, Jonathan D. Buhrman, Hexiang Deng, Lei Yin, Jun Lei, Pengcheng Wei, Kimberly R. Jordan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Tumor vaccines using modified self-antigens that structurally enhance T cell receptor–peptide–major histocompatibility complex interactions greatly improve a T cell protective response against the tumor’s unmodified self-antigen. X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6cc98e7706b3d0d3ebcf81bb9199aa9
https://doi.org/10.1073/pnas.2100588118
https://doi.org/10.1073/pnas.2100588118