Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Shao-Zheng Peng"'
Autor:
Hung-Kai Chen, Li-Ming Lu, Chih-Lun Hsiao, Yin-Ping Wang, Chu-Bin Liao, Shao-Zheng Peng, Huey-Wen Hsiao, Jing-Yi Huang, Daw-Tsun Shih
Publikováno v:
Cancer Research. 79:343-343
We have found that tumor-associated macrophages (TAMs) isolated from metastatic tumors displayed a predominant M2 phenotype. Preclinical studies show that M2-polarized TAMs forge an immunosuppressive microenvironment at metastatic niches to facilitat
Autor:
Mann-Yan Kuo, Shao-Zheng Peng, Sian-Yi Ciou, Ju-Ying Yang, Yen-Hsi Liu, Chu-Bin Liao, Hung-Jyun Huang, Shih Chieh Yen
Publikováno v:
Cancer Research. 78:2809-2809
The oncogenic mutations of BRAF which occur most frequently in V600E, leading to constitutive activation of the MAPK signaling pathway, are common in a variety of human cancers. Recently, drugs targeting RAF kinase have been approved as an effective
Autor:
Chin-Kang Sha, Shao-Zheng Peng
Publikováno v:
ChemInform. 46
Total syntheses of (±)-guanacastepenes N and O were accomplished with 2-cycloheptenone as starting material. The six- and five-membered rings of the core [5, 7, 6] ring skeleton were constructed with an intramolecular Diels–Alder reaction and α-c
Autor:
Chin-Kang Sha, Shao-Zheng Peng
Publikováno v:
Organic letters. 17(14)
Total syntheses of (±)-guanacastepenes N and O were accomplished with 2-cycloheptenone as starting material. The six- and five-membered rings of the core [5, 7, 6] ring skeleton were constructed with an intramolecular Diels–Alder reaction and α-c
Publikováno v:
Current Medicinal Chemistry. 12:1-22
Protein tyrosine phosphatase (PTP) is the family of enzymes that are key players in cellular signal transduction system and perturbation in their functioning is implicated in many disease-states. Diverse chemical compounds are being synthesized and e
Publikováno v:
Current Organic Chemistry. 8:947-976
Autor:
Yu-Kai Chen, Shao-Zheng Peng, Hung-Jyun Huang, Pan Yu-Chih, Jia-Ming Chang, Sian-Yi Ciou, Chen-Hsuan Ho, Chao-Pin Lee, Chu-Bin Liao
Publikováno v:
Cancer Research. 77:3206-3206
Tumor-associated macrophages (TAMs) are major components of leukocytic infiltrate of tumors. It has been reported that high TAMs density is associated with poor clinical prognosis. Within the tumor microenvironment, TAMs rely on signaling through CSF
Autor:
Shao Zheng Peng, Wen Ren Li
Publikováno v:
Tetrahedron Letters. 39:7373-7376
The first general method for the synthesis of a library of trifunctionalized (Z)-3-alkylidene-2,5-piperazinediones as potential protein tyrosine kinase inhibitors from commercially available amino compounds, α-keto acids and aldehydes using a novel
Autor:
Wen Ren Li, Shao Zheng Peng
Publikováno v:
ChemInform. 29
The first general method for the synthesis of a library of trifunctionalized (Z)-3-alkylidene-2,5-piperazinediones as potential protein tyrosine kinase inhibitors from commercially available amino compounds, α-keto acids and aldehydes using a novel