Výsledky vyhledávání - "Shao-Yong Chen"

Akademický článek

Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases

Autor: Giacomo Canesin, Annalisa Di Ruscio, Mailin Li, Simone Ummarino, Andreas Hedblom, Reeham Choudhury, Agnieszka Krzyzanowska, Eva Csizmadia, Macarena Palominos, Anna Stiehm, Alexander Ebralidze, Shao-Yong Chen, Mahmoud A. Bassal, Ping Zhao, Emanuela Tolosano, Laurence Hurley, Anders Bjartell, Daniel G. Tenen, Barbara Wegiel

Publikováno v: Cell Reports, Vol 32, Iss 12, Pp 108181- (2020)

Summary: Hemopexin (Hx) is a scavenger of labile heme. Herein, we present data defining the role of tumor stroma-expressed Hx in suppressing cancer progression. Labile heme and Hx levels are inversely correlated in the plasma of patients with prostat

Externí odkaz: https://doaj.org/article/76000eec6b3949338a7ea5bf4b5f4c5a

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Akademický článek

Interaction between c-jun and androgen receptor determines the outcome of taxane therapy in castration resistant prostate cancer.

Autor: Martina Tinzl, Binshen Chen, Shao-Yong Chen, Julius Semenas, Per-Anders Abrahamsson, Nishtman Dizeyi

Publikováno v: PLoS ONE, Vol 8, Iss 11, p e79573 (2013)

Taxane based chemotherapy is the standard of care treatment in castration resistant prostate cancer (CRPC). There is convincing evidence that taxane therapy affects androgen receptor (AR) but the exact mechanisms have to be further elucidated. Our st

Externí odkaz: https://doaj.org/article/c9fca333663a44018cb8abcfc2d52046

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Rhodium(iii)-catalyzed regioselective C(sp2)–H activation of indoles at the C4-position with iodonium ylides

Autor: Fuhai Wu, Lin Xiao, Hui Xie, Shao-Yong Chen, Jia-Lin Song, Yi-Chuan Zheng, Yan-Zhi Liu, Shang-Shi Zhang

Publikováno v: Organic & Biomolecular Chemistry. 20:5055-5059

Herein, we report a Rh(iii)-catalyzed C4-selective activation of indoles by using iodonium ylides as carbene precursors.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9d0dddeaa61f11e54d8a5a888f8fd99
https://doi.org/10.1039/d2ob00722c

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Rh(iii)-Catalyzed dienylation and cyclopropylation of indoles at the C4 position with alkylidenecyclopropanes

Autor: Yan-Zhi Liu, Yao-Fu Zeng, Bing Shu, Yi-Chuan Zheng, Lin Xiao, Shao-Yong Chen, Jia-Lin Song, Xuanxuan Zhang, Shang-Shi Zhang

Publikováno v: Organic Chemistry Frontiers. 9:4287-4293

Herein, we report a Rh(iii)-catalyzed C–H functionalization of indoles at the C4 position with alkylidenecyclopropanes (ACPs).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::288c6e9c9a419295eb7a5aefca225890
https://doi.org/10.1039/d2qo00763k

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A cascade indazolone-directed Ir(iii)- and Rh(iii)-catalyzed C(sp2)–H functionalization/[4 + 2] annulation of 1-arylindazolones with sulfoxonium ylides to access chemically divergent 8H-indazolo [1,2-a]cinnolines

Autor: Yi-Chuan Zheng, Bing Shu, Yao-Fu Zeng, Shao-Yong Chen, Jia-Lin Song, Yan-Zhi Liu, Lin Xiao, Xu-Ge Liu, Xuanxuan Zhang, Shang-Shi Zhang

Publikováno v: Organic Chemistry Frontiers. 9:5185-5190

An indazolone-directed chemoselective synthesis of 8H-indazolo [1,2-a]cinnolines has been realized via a cascade Cp*Ir(iii)- and Cp*Rh(iii)-catalyzed C–H activation/cyclization reaction of 1-arylindazolones with sulfoxonium ylides.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63cd7d028aecc41432c3f873da7a61f1
https://doi.org/10.1039/d2qo00871h

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