Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shao-Kun Yu"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Chaperonin Containing TCP1 Subunit 6 A (CCT6A) is a prominent protein involved in the folding and stabilization of newly synthesized proteins. However, its roles and underlying mechanisms in lung adenocarcinoma (LUAD), one of the
Externí odkaz:
https://doaj.org/article/ee10134e8f1d4f45819c84e1331d8192
Autor:
Tao Yu, Feng-Qi Nie, Qi Zhang, Shao-Kun Yu, Mei-Ling Zhang, Qian Wang, En-Xiu Wang, Kai-Hua Lu, Ming Sun
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Lung squamous cell carcinoma (LUSC) is a subtype of lung cancer for which precision therapy is lacking. Chimeric antigen receptor T-cells (CAR-T) have the potential to eliminate cancer cells by targeting specific antigens. However, the tumor
Externí odkaz:
https://doaj.org/article/c5ac2f4ddbeb41ffbd69255b82a0e57a
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-13 (2023)
Abstract The THO complex (THOC) is ubiquitously involved in RNA modification and various THOC proteins have been reported to regulate tumor development. However, the role of THOC3 in lung cancer remains unknown. In this study, we identified that THOC
Externí odkaz:
https://doaj.org/article/cd6bb7052d894a17b89f14e85905b0f6
Publikováno v:
Pathology and Oncology Research, Vol 28 (2022)
Background: Solute carrier (SLC) family members are crucial in transporting amino acids across membranes. Amino acids are indispensable for both cancer and immune cells. However, the clinical significance of amino acid transporting SLC members in sto
Externí odkaz:
https://doaj.org/article/efeea8c76d034b4484e6cbdb5dafd1a2
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chimeric antigen receptor (CAR)-T cells have enormous potentials for clinical therapies. The CAR-T therapy has been approved for treating hematological malignancies. However, their application is limited in solid tumors owing to antigen loss and muta
Externí odkaz:
https://doaj.org/article/7ba2a921aa3a43e5a0e25faa8e9f5c2b