Cysteine catabolism and the serine biosynthesis pathway support pyruvate production during pyruvate kinase knockdown in pancreatic cancer cells

Autor: Lei Yu, Shao Thing Teoh, Elliot Ensink, Martin P. Ogrodzinski, Che Yang, Ana I. Vazquez, Sophia Y. Lunt

Publikováno v: Cancer & Metabolism, Vol 7, Iss 1, Pp 1-13 (2019)

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with limited treatment options. Pyruvate kinase, especially the M2 isoform (PKM2), is highly expressed in PDAC cells, but its role in pancreatic cancer remains contro

Externí odkaz: https://doaj.org/article/0dd57d2ce6dc48dd85df26dd36c615c7

Loss of Health Promoting Bacteria in the Gastrointestinal Microbiome of PICU Infants with Bronchiolitis: A Single-Center Feasibility Study

Autor: Madeleine M. Russell, Mara L. Leimanis-Laurens, Sihan Bu, Gigi A. Kinney, Shao Thing Teoh, Ruth-Anne L. McKee, Karen Ferguson, John W. Winters, Sophia Y. Lunt, Jeremy W. Prokop, Surender Rajasekaran, Sarah S. Comstock

Publikováno v: Children, Vol 9, Iss 1, p 114 (2022)

The feasibility of gastrointestinal (GI) microbiome work in a pediatric intensive care unit (PICU) to determine the GI microbiota composition of infants as compared to control infants from the same hospital was investigated. In a single-site observat

Externí odkaz: https://doaj.org/article/032a357f202f4a98b4ad10cc2ebe485e

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Observation of Spin Splitting in Room-Temperature Metallic Antiferromagnet CrSb.

Autor: Zeng M; Department of Physics and Shenzhen Institute for Quantum Science and Engineering (SIQSE), Southern University of Science and Technology (SUSTech), Shenzhen, Guangdong, 518055, China., Zhu MY; Department of Physics and Shenzhen Institute for Quantum Science and Engineering (SIQSE), Southern University of Science and Technology (SUSTech), Shenzhen, Guangdong, 518055, China., Zhu YP; Department of Physics and Shenzhen Institute for Quantum Science and Engineering (SIQSE), Southern University of Science and Technology (SUSTech), Shenzhen, Guangdong, 518055, China., Liu XR; Department of Physics and Shenzhen Institute for Quantum Science and Engineering (SIQSE), Southern University of Science and Technology (SUSTech), Shenzhen, Guangdong, 518055, China., Ma XM; Department of Physics and Shenzhen Institute for Quantum Science and Engineering (SIQSE), Southern University of Science and Technology (SUSTech), Shenzhen, Guangdong, 518055, China., Hao YJ; Department of Physics and Shenzhen Institute for Quantum Science and Engineering (SIQSE), Southern University of Science and Technology (SUSTech), Shenzhen, Guangdong, 518055, China., Liu P; Department of Physics and Shenzhen Institute for Quantum Science and Engineering (SIQSE), Southern University of Science and Technology (SUSTech), Shenzhen, Guangdong, 518055, China., Qu G; Beijing National Laboratory for Condensed Matter Physics and Institute of Physics Chinese Academy of Sciences, Beijing, 100190, China., Yang Y; State Key Laboratory of Functional Materials for Informatics, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050, China., Jiang Z; National Synchrotron Radiation Laboratory and School of Nuclear Science and Technology, University of Science and Technology of China, Hefei, Anhui, 230026, China., Yamagami K; Japan Synchrotron Radiation Research Institute (JASRI), Sayo, Hyogo, 679-5198, Japan., Arita M; Hiroshima Synchrotron Radiation Centre, Hiroshima University, Higashi-Hiroshima, Hiroshima, 739-0046, Japan., Zhang X; Key Laboratory of Quantum Materials and Devices of Ministry of Education, School of Physics, Southeast University, Nanjing, Jiangsu, 211189, China., Shao TH; Department of Physics and Shenzhen Institute for Quantum Science and Engineering (SIQSE), Southern University of Science and Technology (SUSTech), Shenzhen, Guangdong, 518055, China., Dai Y; Department of Physics and Shenzhen Institute for Quantum Science and Engineering (SIQSE), Southern University of Science and Technology (SUSTech), Shenzhen, Guangdong, 518055, China., Shimada K; Hiroshima Synchrotron Radiation Centre, Hiroshima University, Higashi-Hiroshima, Hiroshima, 739-0046, Japan., Liu Z; Shanghai Synchrotron Radiation Facility, Shanghai Advanced Research Institute Chinese Academy of Sciences, Shanghai, 201204, China., Ye M; Shanghai Synchrotron Radiation Facility, Shanghai Advanced Research Institute Chinese Academy of Sciences, Shanghai, 201204, China., Huang Y; Shanghai Synchrotron Radiation Facility, Shanghai Advanced Research Institute Chinese Academy of Sciences, Shanghai, 201204, China., Liu Q; Department of Physics and Shenzhen Institute for Quantum Science and Engineering (SIQSE), Southern University of Science and Technology (SUSTech), Shenzhen, Guangdong, 518055, China., Liu C; Department of Physics and Shenzhen Institute for Quantum Science and Engineering (SIQSE), Southern University of Science and Technology (SUSTech), Shenzhen, Guangdong, 518055, China.

Publikováno v: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Nov; Vol. 11 (43), pp. e2406529. Date of Electronic Publication: 2024 Sep 20.