Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Shao Ning Yang"'
Autor:
Florencia Cayrol, Pannee Praditsuktavorn, Tharu M. Fernando, Nicholas Kwiatkowski, Rosella Marullo, M. Nieves Calvo-Vidal, Jude Phillip, Benet Pera, Shao Ning Yang, Kaipol Takpradit, Lidia Roman, Marcello Gaudiano, Ramona Crescenzo, Jia Ruan, Giorgio Inghirami, Tinghu Zhang, Graciela Cremaschi, Nathanael S. Gray, Leandro Cerchietti
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
T-cell lymphomas are aggressive diseases associated with poor outcome. Here, the authors show that the THZ1, a CDK7 inhibitor, suppresses STAT transcriptional activity leading to apoptosis and sensitization to BCL2 inhibitors in T-cell lymphomas.
Externí odkaz:
https://doaj.org/article/d9b0eca4497a40c1b2e964a28298864d
Autor:
Florencia Cayrol, Pannee Praditsuktavorn, Tharu M. Fernando, Nicholas Kwiatkowski, Rossella Marullo, M. Nieves Calvo-Vidal, Jude Phillip, Benet Pera, Shao Ning Yang, Kaipol Takpradit, Lidia Roman, Marcello Gaudiano, Ramona Crescenzo, Jia Ruan, Giorgio Inghirami, Tinghu Zhang, Graciela Cremaschi, Nathanael S Gray, Leandro Cerchietti
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-1 (2017)
Nature Communications 8: Article number: 14290 (2017); Published: 30 January 2017; Updated: 20 February 2017 The original version of this Article contained an error in the spelling of the author Rossella Marullo, which was incorrectly given as Rosell
Externí odkaz:
https://doaj.org/article/4f6d287b1b314c20bd2687a9811a5e95
Autor:
Leandro Cerchietti, Christine Damm-Welk, Inga Vater, Wolfram Klapper, Lana Harder, Christiane Pott, Shao Ning Yang, Alfred Reiter, Reiner Siebert, Ari Melnick, Willi Woessmann
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18436 (2011)
ALK positive diffuse large B-cell lymphomas (DLBCL) are a distinct lymphoma subtype associated with a poor outcome. Most of them feature a t(2;17) encoding a clathrin (CLTC)-ALK fusion protein. The contribution of deregulated ALK-activity in the path
Externí odkaz:
https://doaj.org/article/6f94016c034448dc9816df728bd9e896
Autor:
Ari Melnick, Iannis Aifantis, Weimin Ci, Olivier Elemento, Ivan Maillard, Patrick A. Zweidler-McKay, John P. Leonard, Kamala Bhatt, Wayne Tam, Zhuoning Li, Eric Perkey, Xabier Agirre, Katerina Hatzi, Yanwen Jiang, Camille W. Graham, Erin Oswald, Shao Ning Yang, Philmo Oh, Leandro Cerchietti, Martín Rivas, Mariano Cardenas, Ling Wang, Huimin Geng, Camille Lobry, Ester Valls
Supplementary Table S8. DLBCL p-values and rho values on GCB-DLBCL probesets for Notch2 pathway genes. (See Supplementary Figure S1G).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42efdd16395832aa1cd1f8e5ff4b8110
https://doi.org/10.1158/2159-8290.22532026.v1
https://doi.org/10.1158/2159-8290.22532026.v1
Autor:
Ari Melnick, Iannis Aifantis, Weimin Ci, Olivier Elemento, Ivan Maillard, Patrick A. Zweidler-McKay, John P. Leonard, Kamala Bhatt, Wayne Tam, Zhuoning Li, Eric Perkey, Xabier Agirre, Katerina Hatzi, Yanwen Jiang, Camille W. Graham, Erin Oswald, Shao Ning Yang, Philmo Oh, Leandro Cerchietti, Martín Rivas, Mariano Cardenas, Ling Wang, Huimin Geng, Camille Lobry, Ester Valls
Supplementary Figure S1. BCL6 displays a specific genomic localization pattern in FL. Supplementary Figure S2. Inverse correlation between BCL6 and NOTCH2 complex genes in primary GC B-cells. Supplementary Figure S3. GC reaction is impaired in Notch2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a421adc5484b4841a2793ce3d9f32c
https://doi.org/10.1158/2159-8290.22532050
https://doi.org/10.1158/2159-8290.22532050
Autor:
Leandro Cerchietti, Scott R. Manalis, Gabriela Chiosis, Giorgio Inghirami, Peter Martin, John P. Leonard, Catherine Thieblemont, Tony Taldone, Lucy Yang, Shao Ning Yang, Jayeshkumar Patel, Nikita Kotlov, Ekaterina Tikhonova, Rossella Marullo, Jude M. Phillip, Maria V. Revuelta, Max A. Stockslager, Jan Krumsiek, Nahuel Zamponi, M. Nieves Calvo-Vidal
Supplementary Table 1, Table 2 and Table 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e1d53e6797cd252b54f45cc51c3fc3
https://doi.org/10.1158/0008-5472.22528806.v1
https://doi.org/10.1158/0008-5472.22528806.v1
Autor:
Leandro Cerchietti, Ari M. Melnick, Masayuki Hirano, Gilbert G. Privé, Balázs Győrffy, Todd Evans, Haelee Ahn, Ingrid Torregroza, Geoffrey Lundell-Smith, Shao Ning Yang, Jude M. Phillip, Benet Pera Gresely, Rossella Marullo, Tharu M. Fernando
Supplementary Figures 1-8 Supplementary Tables 1-2 Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01a311eedd22c4494abb498526c1cf5
https://doi.org/10.1158/2159-8290.22532999.v1
https://doi.org/10.1158/2159-8290.22532999.v1
Autor:
Lucy F. Yang, John P. Leonard, Gabriela Chiosis, M. Nieves Calvo-Vidal, Tony Taldone, Nikita Kotlov, Maria Victoria Revuelta, Catherine Thieblemont, Giorgio Inghirami, Peter Martin, Jan Krumsiek, Shao Ning Yang, Leandro Cerchietti, Rossella Marullo, Ekaterina Tikhonova, Jude M. Phillip, Nahuel Zamponi, Jayeshkumar Patel, Scott R. Manalis, Max A. Stockslager
Publikováno v:
Cancer Res
Prof. Manolis
Prof. Manolis
HSP90 is critical for maintenance of the cellular proteostasis. In cancer cells, HSP90 also becomes a nucleating site for the stabilization of multiprotein complexes including signaling pathways and transcription complexes. Here we described the role
Autor:
Yoon-Chi Han, Pui-Yee Ng, Luisa Shin Ogawa, Shao Ning Yang, Miao Chen, Noboru Ishiyama, Tai-An Lin, Elizabeth Buck
Publikováno v:
Cancer Research. 83:3415-3415
Mutations in BRAF and RAS are often oncogenic and lead to a constitutively active MAPK pathway that promotes aberrant cell proliferation and tumor growth. Currently approved BRAF inhibitors are selective against monomeric BRAF V600 mutants. These dru
Autor:
Ingrid Torregroza, Jude M. Phillip, Leandro Cerchietti, Shao Ning Yang, Rossella Marullo, Tharu M. Fernando, Todd Evans, Haelee Ahn, Geoffrey Lundell-Smith, Ari Melnick, Balázs Győrffy, Masayuki Hirano, Benet Pera Gresely, Gilbert G. Privé
Publikováno v:
Cancer Discov
Several lines of evidence link the canonical oncogene BCL6 to stress response. Here we demonstrate that BCL6 evolved in vertebrates as a component of the HSF1-driven stress response, which has been co-opted by the immune system to support germinal ce