Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Shao Lee Lin"'
Publikováno v:
Nephron. 129:29-33
Background: Most patients with diabetic kidney disease (DKD) experience disease progression despite receiving standard care therapy. Oxidative stress is associated with DKD severity and risk of progression, but currently approved therapies do not dir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24d9a5e975a922cc792324390dd5b5f
https://doi.org/10.1159/000369152
https://doi.org/10.1159/000369152
Autor:
Rob Lambkin-Williams, Shao-Lee Lin, John P. DeVincenzo, Sandra A Lewis, Cecilia Scaglioni-Weinlich, Xiaoming Li, Richard L Mackman, Yan Xin, Lisa Harrison, Srini Ramanathan, Jason W. Chien, Eric Farrell, Robert Jordan, Seth Toback, Richard J. Whitley, Thomas G. O'Riordan, Stephen McBride
Publikováno v:
New England Journal of Medicine. 371:711-722
Respiratory syncytial virus (RSV) is a common cause of infant hospitalizations and is increasingly recognized as a cause of considerable morbidity and mortality. No accepted antiviral treatment exists.We conducted a double-blind, placebo-controlled s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371742cab11dd13f22a187c7260594d8
https://doi.org/10.1056/nejmoa1401184
https://doi.org/10.1056/nejmoa1401184
Autor:
Chamian, Francesca1 mfnchamian@msn.com, Shao-Lee Lin1 shaol@amgen.com, Lee, Edmund1 elee96@yahoo.com, Kikuchi, Toyoko1 kikuchi@rockefeller.edu, Gilleaudeau, Patricia1 gilleap@rockefeller.edu, Sullivan-Whalen, Mary1 whalems@rockefeller.edu, Cardinale, Irma1 cardini@rockefeller.edu, Khatcherian, Artemis1 khatcha@rockefeller.edu, Novitskaya, Inna1 novitsi@rockefeller.edu, Wittkowski, Knut M.1 kmw@rockefeller.edu, Krueger, James G.1 jgk@rockefeller.edu, Lowes, Michelle A.1 lowesm@rockefeller.edu
Publikováno v:
Journal of Translational Medicine. 2007, Vol. 5, p27-7. 7p. 2 Graphs.
Autor:
William W. Busse, Shao-Lee Lin, Joseph Lin, J. Feng, Stephen T. Holgate, Edward Kerwin, Yun Chon
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 188:1294-1302
IL-17 signaling has been implicated in development and persistence of asthma. Cytokine-targeted strategies blocking IL-17 receptor signaling may be beneficial in asthma treatment.To determine efficacy and safety of brodalumab, a human anti-IL-17 rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4f3872655583f14ebc5faaf06bc965
https://doi.org/10.1164/rccm.201212-2318oc
https://doi.org/10.1164/rccm.201212-2318oc
Autor:
Nicola J. Roberts, James D. Lewsey, Michelle Gillies, Andrew H. Briggs, Vasily Belozeroff, Denise R. Globe, Chiun-Fang Chiou, Shao-Lee Lin, Gary Globe
Publikováno v:
Respiratory Medicine. 107(8):1172-1177
Summary Background The risk of case-fatality following hospitalisation for asthma has not been well characterised. We describe trends in 30 day case-fatality following hospitalisation for asthma in adults in Scotland from 1981 to 2009. Methods Using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbcde80ea678e4fd83a5f83ada1adfe
Autor:
Patrick W. Sullivan, Karen L. Smith, Vahram H. Ghushchyan, Denise R. Globe, Shao-Lee Lin, Gary Globe
Publikováno v:
Journal of Asthma. 50:891-899
Given the growing prevalence of asthma in USA, it is important to understand its national burden from the patient's perspective. The objective of this research is to examine the national burden of asthma and poor asthma control on health function, he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1fcd9d2892afcab1322370928bb77c8
https://doi.org/10.3109/02770903.2013.813035
https://doi.org/10.3109/02770903.2013.813035
Autor:
Sally E. Wenzel, Nan Zhang, Edward Kerwin, Mark C. Liu, William W. Busse, Eli O. Meltzer, Yun Chon, Alison L. Budelsky, Shao Lee Lin, Joseph Lin
Publikováno v:
Journal of Allergy and Clinical Immunology. 131:339-345
Background The D-prostanoid receptor and the chemoattractant receptor homologous molecule expressed on T H 2 cells (CRTH2) are implicated in asthma pathogenesis. AMG 853 is a potent, selective, orally bioavailable, small-molecule dual antagonist of h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a7fda70113ce7339635dbd587a3679
https://doi.org/10.1016/j.jaci.2012.10.013
https://doi.org/10.1016/j.jaci.2012.10.013
Autor:
Severine Vermeire, Yi-Hsiang Hsu, Stephan R. Targan, Chris B. Russell, Brian G. Feagan, Carol J. Landers, Dalin Li, Remo Panaccione, Shao-Lee Lin, Richard Newmark, Gil Y. Melmed, Nan Zhang, Yun Chon, Paul Klekotka
Publikováno v:
The American journal of gastroenterology. 111(11)
To assess the safety and efficacy of brodalumab, a human anti-interleukin-17 receptor monoclonal antibody, in patients with moderate-to-severe Crohn's disease (CD).Phase 2, randomized, double-blind, placebo-controlled, dose-ranging study in patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1eded7eb777dd1b6b82d221d05ecbe6
https://pubmed.ncbi.nlm.nih.gov/27481309
https://pubmed.ncbi.nlm.nih.gov/27481309
Autor:
Jill Fredrickson, Brian H. Smith, Megan A. Gibbs, Itzela Correa, Shao-Lee Lin, Todd Barbee, John P. Gibbs
Publikováno v:
The Journal of Clinical Pharmacology. 52:1494-1505
Dipeptidyl peptidase-4 (DPP-4) inhibition is a well- characterized treatment for type 2 diabetes mellitus (T2DM). The objective of this model-based meta-analysis was to describe the time course of HbA1c response after dosing with alogliptin (ALOG), s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecd29acb7457e13b9eaf5d7d38ebe303
https://doi.org/10.1177/0091270011420153
https://doi.org/10.1177/0091270011420153
Autor:
Marta Starcevic, Christopher Banfield, Alex Colbert, Peiming Ma, Cynthia Sung, Michael S. Vincent, Shao-Lee Lin, Tarundeep Kakkar, Thuy Vu, Leonid Gibiansky, Adimoolam Narayanan, Sarah A Hoofring
Publikováno v:
Pharmaceutical Research. 28:2530-2542
For AMG 317, a fully human monoclonal antibody to interleukin receptor IL-4Rα, we developed a population pharmacokinetic (PK) model by fitting data from four early phase clinical trials of intravenous and subcutaneous (SC) routes simultaneously, inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3bcdd788ee1c518f64c8bc0a709322a
https://doi.org/10.1007/s11095-011-0481-y
https://doi.org/10.1007/s11095-011-0481-y