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Akademický článek

mRNA processing in mutant zebrafish lines generated by chemical and CRISPR-mediated mutagenesis produces unexpected transcripts that escape nonsense-mediated decay.

Autor: Jennifer L Anderson, Timothy S Mulligan, Meng-Chieh Shen, Hui Wang, Catherine M Scahill, Frederick J Tan, Shao J Du, Elisabeth M Busch-Nentwich, Steven A Farber

Publikováno v: PLoS Genetics, Vol 13, Iss 11, p e1007105 (2017)

As model organism-based research shifts from forward to reverse genetics approaches, largely due to the ease of genome editing technology, a low frequency of abnormal phenotypes is being observed in lines with mutations predicted to lead to deleterio

Externí odkaz: https://doaj.org/article/113fcbe6ef3a4950b7f16a238692a5a8

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mRNA processing in mutant zebrafish lines generated by chemical and CRISPR-mediated mutagenesis produces unexpected transcripts that escape nonsense-mediated decay

Autor: Catherine M Scahill, Jennifer L. Anderson, Hui Wang, Meng-Chieh Shen, Shao J. Du, Frederick J. Tan, Steven A. Farber, Timothy Mulligan, Elisabeth M. Busch-Nentwich

Publikováno v: PLoS Genetics
PLoS Genetics, Vol 13, Iss 11, p e1007105 (2017)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763c46cb4449f034c0f08c67681fe848
https://pubmed.ncbi.nlm.nih.gov/29470494

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mRNA processing in mutant zebrafish lines generated by chemical and CRISPR-mediated mutagenesis produces potentially functional transcripts

Autor: Meng-Chieh Shen, Elisabeth M. Busch-Nentwich, Catherine M Scahill, Steven A. Farber, Jennifer L. Anderson, Timothy Mulligan, Shao J. Du, Hui Wang

As model organism-based research shifts from forward to reverse genetics approaches, largely due to the ease of genome editing technology, allow frequency of abnormal phenotypes is being observed in lines with mutations predicted to lead to deleterio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccc83429bd297d597cc471405fa790f7
https://doi.org/10.1101/154856

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Knockdown of a galectin-1-like protein in zebrafish (Danio rerio) causes defects in skeletal muscle development

Autor: Gerardo R. Vasta, Shao-J. Du, Hafiz Ahmed

Publikováno v: Glycoconjugate Journal. 26:277-283

We previously identified and characterized four galectin-1-like proteins in zebrafish, Drgal1-L1, Drgal1-L2, Drgal1-L3, and one splice variant of Drgal1-L2, of distinct ontogenic expression. Drgal1-L1 is maternal; Drgal1-L2 is zygotic and strongly ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0973e280be252ce963b44499bb74f130
https://doi.org/10.1007/s10719-008-9178-9

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Galectins in teleost fish: Zebrafish (Danio rerio) as a model species to address their biological roles in development and innate immunity

Autor: Shao J. Du, Hafiz Ahmed, Davin Henrikson, Gerardo R. Vasta

Publikováno v: Glycoconjugate Journal. 21:503-521

Cell surface glycans, such as glycocoproteins and glycolipids, encode information that modulates interactions between cells, or between cells and the extracellular matrix, by specifically regulating the binding to cell surface-associated or soluble c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61afff5e5ceb134b72680383a4ef0b24
https://doi.org/10.1007/s10719-004-5541-7

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