Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Shanze Chen"'
Autor:
Jinyong Wang, Dakai Ling, Lulin Shi, Huayun Li, Minhua Peng, Huihong Wen, Tao Liu, Ruifang Liang, Yongjian Lin, Laiyou Wei, Guangzhi Zhang, Shanze Chen
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Background Ovarian cancer (OC) typically develops an immunosuppressive microenvironment by funtional changes of host immune cells. Dysregulated m6A level is associated with cancer progression via the intrinsic oncogenic pathways. However, th
Externí odkaz:
https://doaj.org/article/cd779173a1154f52bd0def7cbe3f43bc
Publikováno v:
PLoS Biology, Vol 22, Iss 3, p e3002537 (2024)
Defective autophagy is linked to proinflammatory diseases. However, the mechanisms by which autophagy limits inflammation remain elusive. Here, we found that the pan-FGFR inhibitor LY2874455 efficiently activated autophagy and suppressed expression o
Externí odkaz:
https://doaj.org/article/1d6e0c25ef9b4958bd6a68a3f329ce6f
Autor:
Xueqin Huang, Bingbing Sheng, Hemi Tian, Qiuxia Chen, Yingqi Yang, Brian Bui, Jiang Pi, Huaihong Cai, Shanze Chen, Jianglin Zhang, Wei Chen, Haibo Zhou, Pinghua Sun
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 10, Pp 4338-4340 (2023)
Externí odkaz:
https://doaj.org/article/d01eaa62e5a04a9a93fd9029d2cf3978
Autor:
Shanze Chen, Abdullah F.U.H. Saeed, Quan Liu, Qiong Jiang, Haizhao Xu, Gary Guishan Xiao, Lang Rao, Yanhong Duo
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-35 (2023)
Abstract Macrophages exist in various tissues, several body cavities, and around mucosal surfaces and are a vital part of the innate immune system for host defense against many pathogens and cancers. Macrophages possess binary M1/M2 macrophage polari
Externí odkaz:
https://doaj.org/article/7a491539ebda4ca39275e67405ad2620
Autor:
Xueqin Huang, Bingbing Sheng, Hemi Tian, Qiuxia Chen, Yingqi Yang, Brian Bui, Jiang Pi, Huaihong Cai, Shanze Chen, Jianglin Zhang, Wei Chen, Haibo Zhou, Pinghua Sun
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 3, Pp 1303-1317 (2023)
In situ and real-time monitoring of responsive drug release is critical for the assessment of pharmacodynamics in chemotherapy. In this study, a novel pH-responsive nanosystem is proposed for real-time monitoring of drug release and chemo-phototherap
Externí odkaz:
https://doaj.org/article/58b4b4ef76b449e5945cc8cb87f9092a
Autor:
Lin Gao, Shanze Chen, Malin Hong, Wenbin Zhou, Bilan Wang, Junying Qiu, Jinquan Xia, Pan Zhao, Li Fu, Jigang Wang, Yong Dai, Ni Xie, Qinhe Yang, Hsien-Da Huang, Xiang Gao, Chang Zou
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract Triple-negative breast cancer (TNBC) is the most challenging subtype of breast cancer. Various endeavor has been made to explore the molecular biology basis of TNBC. Herein, we reported a novel function of factor Kinectin 1 (KTN1) as a carci
Externí odkaz:
https://doaj.org/article/eb5d43a5f4e24d38b46d473fb315ca14
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Air pollution is one of the major risk factors for lung disease. Microplastics are a ubiquitous environmental pollutant, both indoors and in outdoor air. Microplastics have also been found in human lung tissue and sputum. However, there is a paucity
Externí odkaz:
https://doaj.org/article/a7aff4669b2340b7b20cf852bf2d0db1
Autor:
Li Yu, Lingwei Wang, Guang Hu, Laibin Ren, Chen Qiu, Shun Li, Xiaohui Zhou, Shanze Chen, Rongchang Chen
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Cellular energy metabolism plays a crucial role in the regulation of macrophage polarization and in the execution of immune functions. A recent study showed that Slc6a8-mediated creatine uptake from exogenous supplementation modulates macrophage pola
Externí odkaz:
https://doaj.org/article/99a4bd6465864c75bc08df2e5bb59483
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Skin malignant melanoma is a highly aggressive skin tumor, which is also a major cause of skin cancer-related mortality. It can spread from a relatively small primary tumor and metastasize to multiple locations, including lymph nodes, lungs, liver, b
Externí odkaz:
https://doaj.org/article/3a9a8a2db81a46aca997a28807ed0e6e
Autor:
Lijuan Guo, Shanze Chen, Qingrong Liu, Hongyu Ren, Yuhao Li, Junyue Pan, Yuhan Luo, Tongzhou Cai, Ruofan Liu, Junli Chen, Yi Wang, Xiaoying Wang, Ning Huang, Jingyu Li
Publikováno v:
Thoracic Cancer, Vol 11, Iss 10, Pp 2966-2974 (2020)
Background Macrophage polarization affects tumor growth, metabolism, and many other tumor processes. M1 macrophages can promote antitumor immunity response. Signal transducer and activator of transcription 1 (STAT1) is one of the critical transcripti
Externí odkaz:
https://doaj.org/article/a6893b87eda84c0aae510736d570ecd3