Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Shany Koren"'
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Studying dynamic biological processes requires approaches compatible with the lifetimes of the biochemical transactions under investigation, which can be very short. We describe a genetically encoded system that allows protein neighborhoods to be map
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16b72b3098baf08dfddbb38fa2f37f98
https://doi.org/10.1073/pnas.2219339120
https://doi.org/10.1073/pnas.2219339120
Studying dynamic biological processes requires approaches compatible with the lifetimes of the biochemical transactions under investigation, which can be very short. We describe a genetically encoded system that allows protein interactomes to be capt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d61738b9d38f7bab946f78dd72c3be
Autor:
Ulrich Lehmann, Nadia Harbeck, Elna Kuehnle, Ulrike Nitz, Henriette Christgen, Hans Kreipe, Friedrich Feuerhake, Ronald E. Kates, Jos Jonkers, Matthias Christgen, Silke Glage, Patrick W. B. Derksen, Mirjam C. Boelens, Oleg Gluz, Mieke Raap, Mohammad Bentires-Alj, Shany Koren, Malte Gronewold
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 98(1)
Transcription factor AP-2β (TFAP2B) regulates embryonic organ development and is overexpressed in alveolar rhabdomyosarcoma, a rare childhood malignancy. Gene expression profiling has implicated AP-2β in breast cancer (BC). This study characterizes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d16605f5064f156a674c2c273e1d7f96
https://pubmed.ncbi.nlm.nih.gov/29035379
https://pubmed.ncbi.nlm.nih.gov/29035379
Autor:
Christina Scheel, Zsuzsanna Varga, Michael B. Stadler, Mohamed Bentires-Alj, Sungeun Kim, Daniela Kaup, Kirsten D. Mertz, Adrian Britschgi, Shany Koren, Heike Brinkhaus, Alexandra Vissieres, Ghislain M. C. Bonamy, Joana Pinto Couto, Hans Voshol, Tim Roloff, Stephan Duss, Loren Miraglia, Duvini De Silva, Cédric Leroy, Venkateshwar A. Reddy, Anthony P. Orth
Publikováno v:
Nature
Nature 541, 541-545 (2017)
Nature 541, 541-545 (2017)
Cell fate perturbations underlie many human diseases, including breast cancer(1,2). Unfortunately, the mechanisms by which breast cell fate are regulated are largely unknown. The mammary gland epithelium consists of differentiated luminal epithelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfaecbd14442fc5673ce88a718c01021
https://europepmc.org/articles/PMC6726477/
https://europepmc.org/articles/PMC6726477/
Autor:
Shany Koren, Mohamed Bentires-Alj
Publikováno v:
Molecular cell. 60(4)
Tumor heterogeneity impinges on prognosis, response to therapy, and metastasis. As such, heterogeneity is one of the most important and clinically relevant areas of cancer research. Breast cancer displays frequent intra- and inter-tumor heterogeneity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb30792b9bdc4c0832de39f24268a06e
https://pubmed.ncbi.nlm.nih.gov/26590713
https://pubmed.ncbi.nlm.nih.gov/26590713
Autor:
Mohamed Bentires-Alj, Duvini De Silva, Olulanu H. Aina, Linsey Reavie, Joana Pinto Couto, Tim Roloff, Hubertus Kohler, Adrian Britschgi, Tobias Eichlisberger, Robert D. Cardiff, Shany Koren, Michael B. Stadler
Publikováno v:
Nature. 525(7567)
The adult mouse mammary epithelium contains self-sustained cell lineages that form the inner luminal and outer basal cell layers, with stem and progenitor cells contributing to its proliferative and regenerative potential. A key issue in breast cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c712d3a5b23424207b1fe3f91b6609b
https://pubmed.ncbi.nlm.nih.gov/26266975
https://pubmed.ncbi.nlm.nih.gov/26266975
Autor:
Mohamed Bentires-Alj, Shany Koren
Publikováno v:
The FEBS journal. 280(12)
The phosphoinositide 3-kinase (PI3K) signaling pathway is crucial for cell growth, proliferation, metabolism, and survival, and is frequently deregulated in human cancer, including ~ 70% of breast tumors. PIK3CA, the gene encoding the catalytic subun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b369a4f10da538cb2ed2e5b35808d1
https://pubmed.ncbi.nlm.nih.gov/23384338
https://pubmed.ncbi.nlm.nih.gov/23384338
Publikováno v:
Endocrinology. 152(5)
Serum phosphate levels are regulated by PTH and the fibroblast growth factor 23 (Fgf23)/Klotho endocrine system, which both affect expression of Npt2a and thus the apical reabsorption of phosphate in the proximal renal tubules. In addition to Fgf23,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ff596c89447b5ec1b6797ba087f8d1
https://pubmed.ncbi.nlm.nih.gov/21427221
https://pubmed.ncbi.nlm.nih.gov/21427221
Autor:
Mohamed Bentires-Alj, Matthias Müller, Heike Brinkhaus, Dominique S. Meyer, Shany Koren, Cédric Leroy, Robert D. Cardiff, I. Klebba, Urs Müller
Publikováno v:
Oncogenesis, 2
Oncogenesis, vol 2, iss 9
Oncogenesis
Oncogenesis, vol 2, iss 9
Oncogenesis
The phosphoinositide 3-kinase (PI3K) signaling cascade is a key mediator of cellular growth, survival and metabolism and is frequently subverted in human cancer. The gene encoding for the alpha catalytic subunit of PI3K (PIK3CA) is mutated and/or amp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::432e07db1639efb02b327aa81576d7be
https://doi.org/10.1038/oncsis.2013.38
https://doi.org/10.1038/oncsis.2013.38
Publikováno v:
Bone. 47:S41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4812fe6218c979e6a19920193539b62f
https://doi.org/10.1016/j.bone.2010.04.071
https://doi.org/10.1016/j.bone.2010.04.071