Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Shanti K. Samuel"'
Autor:
Javeed, Siddiqui, Shanti K, Samuel, Brooke, Hayward, Kelly A, Wirka, Kathleen L, Deering, Qing, Harshaw, Amy, Phillips, Michael, Harbour
Publikováno v:
Journal of Managed Care & Specialty Pharmacy. 28:1180-1189
Autor:
Michael Harbour, Javeed Siddiqui, Shanti K. Samuel, Brooke Hayward, Kathleen L. Deering, Amy L. Phillips, Kelly Athayde Wirka, Qing Harshaw
Publikováno v:
AIDS (London, England)
Objective: To understand the prevalence of HIV-associated wasting (HIVAW) in the United States. Design: Medical and pharmacy claims study using IBM MarketScan Commercial, Medicare Supplemental and Medicaid Databases. Methods: Study period: July 2012
Autor:
Steven M. Schmid, Shanti K. Samuel, Donald J. Dykes, Lisa Ann Kraus, William R. Waud, Marie Christine Bissery
Publikováno v:
Investigational New Drugs. 21:259-268
Docetaxel is a new taxoid compound with a broad spectrum of antitumor activity. Previous studies have shown that in vitro treatment of specific human tumor lines with docetaxel is associated with the phosphorylation and inactivation of the bcl-2 prot
Publikováno v:
Biochemistry. 38:5939-5947
Histone acetylation is involved in nuclear processes requiring chromatin remodeling. In chicken erythrocytes, DNA replication has ceased, and active reversible histone acetylation is restricted to transcriptionally active/competent chromatin domains.
Publikováno v:
Journal of Biological Chemistry. 273:29093-29097
In a previous study we showed that the levels of the intermediate filament proteins, cytokeratins 8, 18, and 19, in the nuclear matrix-intermediate filament (NM-IF) fraction from the hormone-dependent and estrogen receptor (ER)-positive human breast
Autor:
Suzanne A. W. Fuqua, Toby M. Sullivan, Steffi Oesterreich, James R. Davie, Shanti K. Samuel, Adrian V. Lee
Publikováno v:
Journal of Cellular Biochemistry. 67:275-286
Since the small heat shock protein hsp27 enhances both growth and drug resistance in breast cancer cells, and is a bad prognostic factor in certain subsets of breast cancer patients, we have characterized the transcriptional regulation of hsp27, with
Publikováno v:
Journal of Cellular Biochemistry. 66:9-15
The nuclear matrix, besides providing the structural support of the nucleus, is involved in various cellular functions of the nucleus. Nuclear matrix proteins (NMPs), which are both tissue- and cell type-specific, are altered with transformation and
Autor:
Eva A. Turley, N. Khalil, Robert A. R. Hurta, Shanti K. Samuel, Paturu Kondaiah, J. A. Wright, A. H. Greenberg
Publikováno v:
The EMBO Journal. 11:1599-1605
An expression vector was constructed in which TGF-beta 1 was placed under the control of the metallothionein promoter. Cys223 and Cys225 in the TGF-beta 1 propeptide were converted to serines, mutations which result in dissociation of the pro-peptide
Publikováno v:
Journal of Biological Chemistry. 266:24097-24100
Previous investigations have indicated that the suppression of proliferation by transforming growth factor (TGF) beta 1 is often lost upon cellular transformation, and that proliferation of some tumors is stimulated by TGF-beta. The present study pro
Autor:
Ramanda Upshaw, Zhican Qu, Jaideep V. Thottassery, Yanjie Sun, Marina Manuvakhova, Sarah S. Rentz, Shanti K. Samuel, Louise Westbrook, Amanda Cunningham, Francis G. Kern
Publikováno v:
Cancer research. 64(13)
Increased growth factor receptor signaling is implicated in antiestrogen-resistant breast tumors suggesting that abrogation of such signaling could restore or prolong sensitivity to antihormonal agents. Activation of the mitogen-activated protein/ext