Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Shanthie Thamotharan"'
Autor:
Shubhamoy Ghosh, Shanthie Thamotharan, Jeanette Fong, Margarida Y. Y. Lei, Carla Janzen, Sherin U. Devaskar
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract In a prospective cohort of subjects who subsequently developed preeclampsia (PE, n = 14) versus remaining healthy (NORM, n = 12), early gestation circulating extracellular vesicles (EVs) containing a panel of microRNA signatures were charact
Externí odkaz:
https://doaj.org/article/7d1ca48d3456430d8f6a1f2599459211
Autor:
Giorgia Del Vecchio, Qingjiao Li, Wenyuan Li, Shanthie Thamotharan, Anela Tosevska, Marco Morselli, Kyunghyun Sung, Carla Janzen, Xianghong Zhou, Matteo Pellegrini, Sherin U. Devaskar
Publikováno v:
Epigenetics, Vol 16, Iss 6, Pp 642-661 (2021)
Although analysis of maternal plasma cell-free content has been employed for screening of genetic abnormalities within a pregnancy, limited attention has been paid to its use for the detection of adverse pregnancy outcomes (APOs) based on placental f
Externí odkaz:
https://doaj.org/article/6e54e87db55d4f039b84478cd3ab9356
Autor:
Shanthie Thamotharan, Shubhamoy Ghosh, Laura James-Allan, Margarida Y. Y. Lei, Carla Janzen, Sherin U. Devaskar
Publikováno v:
PLoS ONE, Vol 17, Iss 5 (2022)
We undertook a prospective temporal study collecting blood samples from consenting pregnant women, to test the hypothesis that circulating extracellular vesicles (EVs) carrying specific non-coding microRNA signatures can underlie gestational diabetes
Externí odkaz:
https://doaj.org/article/2862e26971574e7f8f1b29ffe796cf71
Autor:
Shanthie Thamotharan, Alison Chu, Katie Kempf, Carla Janzen, Tristan Grogan, David A Elashoff, Sherin U Devaskar
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176493 (2017)
Placental insufficiency leading to intrauterine growth restriction (IUGR) demonstrates perturbed gene expression affecting placental angiogenesis and nutrient transfer from mother to fetus. To understand the post-transcriptional mechanisms underlying
Externí odkaz:
https://doaj.org/article/e61f6efa2c004208aabc5dc2bfd925ef
Autor:
Carla Janzen, Margarida Y. Y. Lei, Brian R. Lee, Sitaram Vangala, Irish DelRosario, Qi Meng, Beate Ritz, Jonathan Liu, Michael Jerrett, Teresa Chanlaw, Sarah Choi, Arya Aliabadi, Precious Ann Fortes, Peggy S. Sullivan, Aisling Murphy, Giorgia Del Vecchio, Shanthie Thamotharan, KyungHyun Sung, Sherin U. Devaskar
Publikováno v:
American journal of perinatology.
The aim of Placental Assessment in Response to Environmental Pollution Study (PARENTs) was to determine whether imaging of the placenta by novel multiparametric magnetic resonance imaging (MRI) techniques in early pregnancy could help predict adverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb119986acfd9fa173591960e5ab43b5
https://pubmed.ncbi.nlm.nih.gov/36241211
https://pubmed.ncbi.nlm.nih.gov/36241211
Publikováno v:
The Journal of nutrition, vol 150, iss 5
J Nutr
J Nutr
BackgroundThere is evidence that microRNA (MIR) 122 is a biomarker for various liver diseases in adults and children. To date, MIR122 has not been explored in children with intestinal failure-associated liver disease (IFALD, or hyperbilirubinemia ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::665e35c27833ae7bf8f0bf49751f88ff
https://doi.org/10.1093/jn/nxaa001
https://doi.org/10.1093/jn/nxaa001
Autor:
Shanthie Thamotharan, Sherin U. Devaskar, Satish C. Kalhan, Kara L. Calkins, Bo-Chul Shin, Yun Dai
Publikováno v:
Nutrition Research. 54:93-104
Intrauterine growth restriction is linked to decreased lean body mass and insulin resistance. The mammalian target of rapamycin (mTOR) regulates muscle mass and glucose metabolism; however, little is known about maternal dietary restriction and skele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a36be83e807c8eac2bf8851d139bd54
https://doi.org/10.1016/j.nutres.2018.03.013
https://doi.org/10.1016/j.nutres.2018.03.013
Autor:
Andrew Frew, Shanthie Thamotharan, Jingjing Zhang, Bo-Chul Shin, Carlos Cepeda, Jeffry R. Alger, Yun Dai, Sudatip Kositamongkol, Michael S. Levine, Yuanzi Zhao, Monica Sondhi, Raman Sankar, Andrey Mazarati, Sherin U. Devaskar, Peter M. Clark, Masatoshi Tomi, Elizabeth A. Wang, Leah Leibovitch
Publikováno v:
Endocrinology. 158:936-949
We tested the hypothesis that exposure of glut3+/− mice to a ketogenic diet ameliorates autism-like features, which include aberrant behavior and electrographic seizures. We first investigated the life course sex-specific changes in basal plasma–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c71fccbcc0ea123b97790bbaa09997e4
https://doi.org/10.1210/en.2016-1816
https://doi.org/10.1210/en.2016-1816
Autor:
Sherin U. Devaskar, Matteo Pellegrini, Larry Lam, Amit Ganguly, Wen-Wei Liao, Dennis Montoya, Alison Chu, Fei-Man Hsu, Shanthie Thamotharan, Carla Janzen, Pao-Yang Chen, Liudmilla Rubbi
Publikováno v:
Reproductive sciences (Thousand Oaks, Calif.), vol 25, iss 4
Inherent genetic programming and environmental factors affect fetal growth in utero. Epidemiologic data in growth-altered fetuses, either intrauterine growth restricted (IUGR) or large for gestational age (LGA), demonstrate that these newborns are at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f4fa48115d364032efa9c54f011de2
https://escholarship.org/uc/item/6rc1w6m3
https://escholarship.org/uc/item/6rc1w6m3
Publikováno v:
Journal of Cellular Biochemistry. 116:566-579
Intrauterine growth restriction leads to the development of adult onset obesity/metabolic syndrome, diabetes mellitus, cardiovascular disease, hypertension, stroke, dyslipidemia, and non-alcoholic fatty liver disease/steatohepatitis. Continued postna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c758b3567cda570caefbca8da5cb8a0
https://doi.org/10.1002/jcb.25008
https://doi.org/10.1002/jcb.25008