Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Shantelle L. LaFayette"'
Autor:
Émilie Maillé, Manon Ruffin, Damien Adam, Hatem Messaoud, Shantelle L. Lafayette, Geoffrey McKay, Dao Nguyen, Emmanuelle Brochiero
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
The function of cystic fibrosis transmembrane conductance regulator (CFTR) channels is crucial in human airways. However unfortunately, chronic Pseudomonas aeruginosa infection has been shown to impair CFTR proteins in non-CF airway epithelial cells
Externí odkaz:
https://doaj.org/article/77d9d3aca52049d0b9a71fd3b3c1d4b4
Autor:
Lisa C Hennemann, Shantelle L LaFayette, Julien K Malet, Perrine Bortolotti, Tianxiao Yang, Geoffrey A McKay, Daniel Houle, Danuta Radzioch, Simon Rousseau, Dao Nguyen
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009375 (2021)
Pseudomonas aeruginosa causes chronic airway infections, a major determinant of lung inflammation and damage in cystic fibrosis (CF). Loss-of-function lasR mutants commonly arise during chronic CF infections, are associated with accelerated lung func
Externí odkaz:
https://doaj.org/article/bf90d258e3c04ab581f8f7448141615d
Autor:
Perrine Bortolotti, Simon Rousseau, Lisa C. Hennemann, Daniel Houle, Danuta Radzioch, Shantelle L. LaFayette, Geoffrey McKay, Dao Nguyen, Tianxiao Yang, Julien K. Malet
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 3, p e1009375 (2021)
PLoS Pathogens, Vol 17, Iss 3, p e1009375 (2021)
Pseudomonas aeruginosa causes chronic airway infections, a major determinant of lung inflammation and damage in cystic fibrosis (CF). Loss-of-function lasR mutants commonly arise during chronic CF infections, are associated with accelerated lung func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c996e78bcf07c304ac397d0faf15b608
https://doi.org/10.1371/journal.ppat.1009375
https://doi.org/10.1371/journal.ppat.1009375
Autor:
Dao Nguyen, Claudia Bilodeau, Émilie Maillé, Nguyen Thu Ngan Trinh, Martin-Yvon Desrosiers, Geoffrey McKay, Shantelle L. LaFayette, Emmanuelle Brochiero, Simon Rousseau, Manon Ruffin, Trevor Beaudoin
Publikováno v:
The FASEB Journal. 30:3011-3025
Chronic Pseudomonas aeruginosa lung infections are associated with progressive epithelial damage and lung function decline. In addition to its role in tissue injury, the persistent presence of P. aeruginosa–secreted products may also affect epithel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ddf7196719df32a0fe40a5dd554430
https://doi.org/10.1096/fj.201500166r
https://doi.org/10.1096/fj.201500166r
Publikováno v:
Frontiers in Cell and Developmental Biology
Pseudomonas aeruginosa are gram-negative bacteria that frequently infect the lungs of cystic fibrosis (CF) patients. This bacterium is highly responsive to changes in its environment, resulting in the expression of a diverse array of genes that may c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f540e35ad5a2145dd204df7835e36d
http://europepmc.org/articles/PMC5177610
http://europepmc.org/articles/PMC5177610
Autor:
Shantelle L, LaFayette, Daniel, Houle, Trevor, Beaudoin, Gabriella, Wojewodka, Danuta, Radzioch, Lucas R, Hoffman, Jane L, Burns, Ajai A, Dandekar, Nicole E, Smalley, Josephine R, Chandler, James E, Zlosnik, David P, Speert, Joanie, Bernier, Elias, Matouk, Emmanuelle, Brochiero, Simon, Rousseau, Dao, Nguyen
Publikováno v:
Science Advances
Cystic fibrosis–adapted Pseudomonas aeruginosa lasR quorum sensing mutants cause hyperinflammation contributing to chronic lung disease.
Cystic fibrosis lung disease is characterized by chronic airway infections with the opportunistic pathogen
Cystic fibrosis lung disease is characterized by chronic airway infections with the opportunistic pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa8bfd1f9a2a2e88433647cdee5cc03f
https://pubmed.ncbi.nlm.nih.gov/26457326
https://pubmed.ncbi.nlm.nih.gov/26457326
Autor:
David P. Speert, Elias Matouk, Danuta Radzioch, Dao Nguyen, Nicole E. Smalley, Daniel Houle, Simon Rousseau, Gabriella Wojewodka, Lucas R. Hoffman, Shantelle L. LaFayette, Emmanuelle Brochiero, James E. A. Zlosnik, Jane L. Burns, Trevor Beaudoin, Josephine R. Chandler, Joanie Bernier, Ajai A. Dandekar
Publikováno v:
Science Advances. 1
Cystic fibrosis lung disease is characterized by chronic airway infections with the opportunistic pathogen Pseudomonas aeruginosa and severe neutrophilic pulmonary inflammation. P. aeruginosa undergoes extensive genetic adaptation to the cystic fibro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b956f615480666df81226636d6667269
https://doi.org/10.1126/sciadv.1500199
https://doi.org/10.1126/sciadv.1500199
Autor:
Samuel M. Chekabab, Shantelle L. LaFayette, Simon Rousseau, Dao Nguyen, Richard J. Silverman, Yishan Luo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 9, p e0137753 (2015)
PLoS ONE, Vol 10, Iss 9, p e0137753 (2015)
Pseudomonas aeruginosa (PA) and Staphylococcus aureus (SA) are major respiratory pathogens and can concurrently colonize the airways of patients with chronic obstructive diseases, such as cystic fibrosis (CF). Airway epithelial cell signalling is cri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d2e3f7c417e84e20f4438ba1313018f
https://pubmed.ncbi.nlm.nih.gov/26360879
https://pubmed.ncbi.nlm.nih.gov/26360879
Autor:
Dao Nguyen, Shantelle L. LaFayette, Simon Rousseau, Martin Desrosiers, Julie Bérubé, Lucie Roussel, Trevor Beaudoin
Publikováno v:
The Journal of infectious diseases. 207(10)
Biofilm microcolonies of Pseudomonas aeruginosa chronically infect the airways of patients with cystic fibrosis and fuel ongoing destructive inflammation, yet the impact of the switch from planktonic to biofilm growth on host responses is poorly unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff96a178ff4729fb47ca908cdb3045b
https://pubmed.ncbi.nlm.nih.gov/23402824
https://pubmed.ncbi.nlm.nih.gov/23402824
Publikováno v:
Biochemical and biophysical research communications. 428(1)
The presence of the mucoid phenotype of Pseudomonas aeruginosa is a marker of poor survival in cystic fibrosis. As CF lung disease results from chronic infection leading to airway inflammation, we determined whether the switch to a mucoid phenotype b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f148b7c41522318894a4077c64f99a7d
https://pubmed.ncbi.nlm.nih.gov/23068105
https://pubmed.ncbi.nlm.nih.gov/23068105