Výsledky vyhledávání - "Shantanu Balkundi"

Pulmonary sustained release of insulin from microparticles composed of polyelectrolyte layer-by-layer assembly

Autor: Shantanu Balkundi, Kiran Amancha, Alamdar Hussain, Yuri Lvov

Publikováno v: International Journal of Pharmaceutics. 466:96-108

The present study tests the hypothesis that layer-by-layer (LbL) nanoassembly of thin polyelectrolyte films on insulin particles provides sustained release of the drug after pulmonary delivery. LbL insulin microparticles were formulated using cationi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65698102e10d85d5c33f2a2adf4ed41
https://doi.org/10.1016/j.ijpharm.2014.02.006

Zobrazit plný text záznamu

Macrophage folate receptor-targeted antiretroviral therapy facilitates drug entry, retention, antiretroviral activities and biodistribution for reduction of human immunodeficiency virus infections

Autor: Ram S. Veerubhotla, Alexander V. Kabanov, Shantanu Balkundi, Xin Ming Liu, Howard E. Gendelman, Lindsey M. Kendrick, JoEllyn M McMillan, Tatiana K. Bronich, Pavan Puligujja, Nathan Smith, Benson J Edagwa, Tianyuzi Li

Publikováno v: Nanomedicine: Nanotechnology, Biology and Medicine. 9:1263-1273

Macrophages serve as vehicles for the carriage and delivery of polymer-coated nanoformulated antiretroviral therapy (nanoART). Although superior to native drug, high drug concentrations are required for viral inhibition. Herein, folate-modified riton

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52748a3376bd1fbe71b4c61fadc34af6
https://doi.org/10.1016/j.nano.2013.05.003

Zobrazit plný text záznamu

Preclinical Pharmacokinetics and Tissue Distribution of Long-Acting Nanoformulated Antiretroviral Therapy

Autor: Howard S. Fox, Howard E. Gendelman, Shantanu Balkundi, Benjamin G. Lamberty, JoEllyn M McMillan, Xin Ming Liu, Nathan Smith, Brenda Morsey, Dongwei Guo, Pavan Puligujja, Nagsen Gautam, Upal Roy, Yazen Alnouti

Publikováno v: Antimicrobial Agents and Chemotherapy. 57:3110-3120

Long-acting injectable nanoformulated antiretroviral therapy (nanoART) was developed with the explicit goal of improving medicine compliance and for drug targeting of viral tissue reservoirs. Prior nanoART studies completed in humanized virus-infecte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cad57ed8848515a9c8ffda10264f689
https://doi.org/10.1128/aac.00267-13

Zobrazit plný text záznamu

Long-acting nanoformulated antiretroviral therapy elicits potent antiretroviral and neuroprotective responses in HIV-1-infected humanized mice

Autor: Larisa Y. Poluektova, Prasanta K. Dash, JoEllyn M McMillan, Yazen Alnouti, Shantanu Balkundi, Upal Roy, Howard E. Gendelman, Santhi Gorantla, R.L. Mosley, Harris A. Gelbard

Publikováno v: AIDS. 26:2135-2144

Objectives Long-acting nanoformulated antiretroviral therapy (nanoART) with improved pharmacokinetics, biodistribution and limited systemic toxicities will likely improve drug adherence and access to viral reservoirs. Design Atazanavir and ritonavir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ec158098cf634bd85b3b26ffcd6344c
https://doi.org/10.1097/qad.0b013e328357f5ad

Zobrazit plný text záznamu

Comparative manufacture and cell-based delivery of antiretroviral nanoformulations

Autor: Georgette D. Kanmogne, Tatiana K. Bronich, Alexander V. Kabanov, Xin Ming Liu, Ram S. Veerubhotla, Andrea Martinez-Skinner, Shantanu Balkundi, Han Chen, R. Lee Mosley, Upal Roy, JoEllyn M McMillan, Ari S. Nowacek, Howard E. Gendelman

Publikováno v: International Journal of Nanomedicine
Scopus-Elsevier
International Journal of Nanomedicine, Vol 2011, Iss default, Pp 3393-3404 (2011)

Shantanu Balkundi1, Ari S Nowacek1, Ram S Veerubhotla1, Han Chen2, Andrea Martinez-Skinner1, Upal Roy1, R Lee Mosley1,3, Georgette Kanmogne1, Xinming Liu1,3,4, Alexander V Kabanov3,4, Tatiana Bronich3,4, JoEllyn McMillan1, Howard E Gendelman1,31Depar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c8177d556ab1d254e99f7bdf299fa2
http://europepmc.org/articles/PMC3260033

Zobrazit plný text záznamu

Pharmacotoxicology of monocyte-macrophage nanoformulated antiretroviral drug uptake and carriage

Autor: JoEllyn M McMillan, Barrett E. Rabinow, Sangya Singh, Ari S. Nowacek, Shantanu Balkundi, Howard E. Gendelman, Rafael Bressani, Georgette D. Kanmogne

Publikováno v: Nanotoxicology. 5:592-605

Limitations inherent to antiretroviral therapy (ART) in its pharmacokinetic properties remain despite over 15 years of broad use. Our laboratory has pioneered a means to improve ART delivery through monocyte-macrophage carriage of nanoformulated drug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4639c608f1742231602cb47b6e615c65
https://doi.org/10.3109/17435390.2010.541292

Zobrazit plný text záznamu

Layer-by-Layer Nano-Encapsulation of Microbes: Controlled Cell Surface Modification and Investigation of Substrate Uptake in Bacteria

Autor: Shantanu Balkundi, Bettina Franz, Yuri Lvov, Christiane Dahl, Alexander Prange

Publikováno v: Macromolecular Bioscience. 10:164-172

LbL nano self-assembly coating of A. vinosum with different polyelectrolyte combinations is presented as an example to investigate substrate uptake in bacteria. The effects of surface charge and the formation of a physical barrier provides new insigh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7082bee84e61c521b98d77ce923e4ad9
https://doi.org/10.1002/mabi.200900142

Zobrazit plný text záznamu

Layer-by-Layer-Coated Gelatin Nanoparticles as a Vehicle for Delivery of Natural Polyphenols

Autor: Rebecca L. H. Bigelow, D. Patrick O'Neal, Shantanu Balkundi, Yuri Lvov, James A. Cardelli, Joshua J. Steffan, Tatsiana Shutava, Pranitha Vangala

Publikováno v: ACS Nano. 3:1877-1885

Natural polyphenols with previously demonstrated anticancer potential, epigallocatechin gallate (EGCG), tannic acid, curcumin, and theaflavin, were encased into gelatin-based 200 nm nanoparticles consisting of a soft gel-like interior with or without

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f347c56b5729576f930933e89b67021
https://doi.org/10.1021/nn900451a

Zobrazit plný text záznamu

Encapsulation of Bacterial Spores in Nanoorganized Polyelectrolyte Shells

Autor: Nalinkanth G. Veerabadran, Yuri Lvov, Shantanu Balkundi, D. Matthew Eby, Glenn R. Johnson

Publikováno v: Langmuir. 25:14011-14016

Layer-by-layer assembly uses alternating charged layers of polyionic polymers to coat materials sequentially in a sheath of functionalized nanofilms. Bacterial spores were encapsulated in organized ultrathin shells using layer-by-layer assembly in or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08743a1a0ee7b0411224570cd511f206
https://doi.org/10.1021/la900971h

Zobrazit plný text záznamu

Polypeptide Multilayer Films: Role of Molecular Structure and Charge

Autor: Kiran Chakravarthula, Shantanu Balkundi, Naveen Palath, Donald T. Haynie, Komal Dave

Publikováno v: Langmuir. 20:4540-4547

The role of molecular structure, charge, and hydrophobicity in polyelectrolyte layer-by-layer assembly (LbL) of thin films has been studied using the model polypeptides poly-L-glutamatic acid (PLGA) and poly-L-lysine (PLL), quartz crystal microbalanc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f3e85fd6c9836029e799cc69507da0
https://doi.org/10.1021/la036330p

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání