Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Shanta Sarfare"'
Autor:
Debora L. Nickla, Frances Rucker, Christopher P. Taylor, Shanta Sarfare, William Chen, Jonathan Elin-Calcador, Xia Wang
Publikováno v:
Exp Eye Res
Recent evidence indicates that moderate levels of blue light are sufficient to suppress the nighttime rise in serum melatonin in humans, suggesting that luminous screens may be deleterious to sleep cycles and to other functions. Little is known howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8194e8d92afa877101ecbe214c81f83
https://europepmc.org/articles/PMC8957570/
https://europepmc.org/articles/PMC8957570/
Publikováno v:
Exp Eye Res
Evidence suggests that the relevant variable in the anti-myopigenic effect of increased time spent outdoors is the increase in light intensity. Because light is the strongest Zeitgeber, it is plausible that the effects of bright light exposure depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9d4349b54d565883c59408358d198b
https://europepmc.org/articles/PMC9387149/
https://europepmc.org/articles/PMC9387149/
Publikováno v:
Proceedings of the National Academy of Sciences. 114:3987-3992
Recessive Stargardt macular degeneration (STGD1) is caused by mutations in the gene for the ABCA4 transporter in photoreceptor outer segments. STGD1 patients and Abca4−/− (STGD1) mice exhibit buildup of bisretinoid-containing lipofuscin pigments
Autor:
Monte J. Radeke, T. Michael Redmond, William Samuel, Silvia C. Finnemann, Marcia Lloyd, Jane Hu, Cynthia Jaworski, Sze Yin Ng, Zhichun Jiang, Tamara L. Lenis, Dean Bok, Roxana A. Radu, Shanta Sarfare, Nicholas J. Esposito, Gabriel H. Travis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 47
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance Recessive Stargardt macular degeneration (STGD1) and a subset of cone–rod dystrophies are caused by mutations in the Abca4 gene. The ABCA4 protein is a flippase in photoreceptor cells that helps eliminate retinaldehyde, a toxic photopr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8251b92cb707be43ecb2aa9d9aa30fb7
https://escholarship.org/uc/item/22h745hj
https://escholarship.org/uc/item/22h745hj
Autor:
Shanta Sarfare, Jonathan Elin-Calcador, P.M. Iuvone, Jendayi A Dixon, Susov Dhakal, Maureen G. Maguire, Richard A. Stone, Li He, Brendan McGeehan, Wenjie Wei, Debora L. Nickla
Publikováno v:
Exp Eye Res
In chicks, the diurnal patterns of retinal dopamine synthesis and release are associated with refractive development. To assess the within-day patterns of dopamine release, we assayed vitreal levels of DOPAC (3,4-dihydroxyphenylacetic acid) using hig
Autor:
Shanta Sarfare, Wenjie Wei, P. Michael Iuvone, Tejvir S. Khurana, Maureen G. Maguire, Brendan McGeehan, Debora L. Nickla, K. Cameron Engelhart, Richard A. Stone
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Stimulated by evidence implicating diurnal/circadian rhythms and light in refractive development, we studied the expression over 24 hours of selected clock and circadian rhythm-related genes in retina/retinal pigment epithelium (RPE) and chor
Autor:
Joanna J. Kaylor, Shanta Sarfare, C Nathaniel Roybal, Paul Kim, Tongzhou Xu, Samer Habib, Gabriel H. Travis, Steven Nusinowitz, Jeremy D. Cook, Anita Kim, Anh Miu, Quan Yuan, Jacob Makshanoff
Publikováno v:
Nature chemical biology
Nature chemical biology, vol 9, iss 1
Nature chemical biology, vol 9, iss 1
Absorption of a light particle by an opsin-pigment causes photoisomerization of its retinaldehyde chromophore. Restoration of light sensitivity to the resulting apo-opsin requires chemical re-isomerization of the photobleached chromophore. This is ca
Publikováno v:
Journal of clinical & experimental ophthalmology, vol 6, iss 5
Objective: The aim of this study is to evaluate the retinal safety and toxicity of a novel synthetic biopolymer to be used as a patch to treat rhegmatogenous retinal detachment. Methods: Thirty one adult wild type albino mice were divided in 2 groups
Autor:
Timothy W. Kraft, G. R. Rubin, Steven J. Pittler, Alex S. McKeown, Hongjun Wei, Shanta Sarfare, Jeffrey D. Messinger
Publikováno v:
Cell Communication and Signaling : CCS
Background The rod photoreceptor cGMP-gated cation channel, consisting of three α- and one β subunit, controls ion flow into the rod outer segment (ROS). In addition to the β-subunit, the Cngb1 locus encodes an abundant soluble protein, GARP2 that
Autor:
Shanta Sarfare, Gordon L. Fain, Timothy W. Kraft, Youwen Zhang, Robert S. Molday, Laurie L. Molday, Michael L. Woodruff, Steven J. Pittler
Ion flow into the rod photoreceptor outer segment (ROS) is regulated by a member of the cyclic-nucleotide-gated cation-channel family; this channel consists of two subunit types, alpha and beta. In the rod cells, the Cngb1 locus encodes the channel b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e5d464f1c43aa1f9ef7a01084060c92
https://europepmc.org/articles/PMC2778734/
https://europepmc.org/articles/PMC2778734/