Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Shanta Mancham"'
Autor:
Lisanne Noordam, Monique T.A. de Beijer, Shanta Mancham, Isabel Vogler, Patrick P.C. Boor, Valeska de Ruiter, Robbie Luijten, Jan N.M. IJzermans, Ugur Sahin, Marco J. Bruno, Dave Sprengers, Sonja I. Buschow, Jaap Kwekkeboom
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related deaths worldwide due to high recurrence rates after curative treatment and being frequently diagnosed at an advanced stage. Immune-checkpoint inhibition (ICPI) has yielded i
Externí odkaz:
https://doaj.org/article/157b3da14c4742598e466ea3411e9ddf
Autor:
Lisanne Noordam, Zhouhong Ge, Hadiye Özturk, Michail Doukas, Shanta Mancham, Patrick P. C. Boor, Lucia Campos Carrascosa, Guoying Zhou, Thierry P. P. van den Bosch, Qiuwei Pan, Jan N. M. IJzermans, Marco J. Bruno, Dave Sprengers, Jaap Kwekkeboom
Publikováno v:
Cancers, Vol 13, Iss 10, p 2499 (2021)
High recurrence rates after resection of hepatocellular carcinoma (HCC) with curative intent impair clinical outcomes of HCC. Cancer/testis antigens (CTAs) are suitable targets for cancer immunotherapy if selectively expressed in tumor cells. The aim
Externí odkaz:
https://doaj.org/article/454cef315927479f8dc2534eaa0ebc5d
Autor:
Guoying Zhou, Lisanne Noordam, Dave Sprengers, Michail Doukas, Patrick P. C. Boor, Adriaan A. van Beek, Remco Erkens, Shanta Mancham, Dirk Grünhagen, Anand G. Menon, Johan F. Lange, Pim J. W. A. Burger, Alexandra Brandt, Boris Galjart, Cornelis Verhoef, Jaap Kwekkeboom, Marco J. Bruno
Publikováno v:
OncoImmunology, Vol 7, Iss 7 (2018)
Purpose: Liver metastasis develops in >50% of patients with colorectal cancer (CRC), and is a leading cause of CRC-related mortality. We aimed to identify which inhibitory immune checkpoint pathways can be targeted to enhance functionality of intra-t
Externí odkaz:
https://doaj.org/article/860f7b5822ba4d95acd8859e33f3e7a5
Autor:
Kostandinos Sideras, Katharina Biermann, Joanne Verheij, Bart R. Takkenberg, Shanta Mancham, Bettina E. Hansen, Hannah M. Schutz, Robert A. de Man, Dave Sprengers, Sonja I. Buschow, Maddy C. M. Verseput, Patrick P. C. Boor, Qiuwei Pan, Thomas M. van Gulik, Turkan Terkivatan, Jan N. M. Ijzermans, Ulrich H. W. Beuers, Stefan Sleijfer, Marco J. Bruno, Jaap Kwekkeboom
Publikováno v:
OncoImmunology, Vol 6, Iss 2 (2017)
Novel systemic treatments for hepatocellular carcinoma (HCC) are strongly needed. Immunotherapy is a promising strategy that can induce specific antitumor immune responses. Understanding the mechanisms of immune resistance by HCC is crucial for devel
Externí odkaz:
https://doaj.org/article/5f8e3ae8e9ab4fa2a3ac206ae24b7197
Autor:
Ozlem Tapirdamaz, Shanta Mancham, Luc J W van der Laan, Geert Kazemier, Kris Thielemans, Herold J Metselaar, Jaap Kwekkeboom
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14452 (2010)
Conventional assays for quantification of allo-reactive T-cell precursor frequencies (PF) are relatively insensitive. We present a robust assay for quantification of PF of T-cells with direct donor-specificity, and establish the kinetics of circulati
Externí odkaz:
https://doaj.org/article/71bf0cd4bc3647e6be392ce92bbed61c
Autor:
Michail Doukas, Robert A. de Man, Maikel P. Peppelenbosch, Dave Sprengers, Robert J. de Knegt, Dave L. Roelen, Patrick P.C. Boor, Michiel G. H. Betjes, Simone H. Brand-Schaaf, Jaap Kwekkeboom, Nicolle H.R. Litjens, Shanta Mancham, Mariska Klepper, Aafke A. Duizendstra
Publikováno v:
Liver Transplantation, 28(1), 98-112. WILEY
Liver Transplantation, 28(1), 98-112. John Wiley & Sons Ltd.
Liver Transplantation, 28(1), 98-112. John Wiley & Sons Ltd.
Spontaneous operational tolerance to the allograft develops in a proportion of liver transplantation (LT) recipients weaned off immunosuppressive (IS) drugs. Several studies have investigated whether peripheral blood circulating T cells could play a
Autor:
M. Hosein Aziz, Xingxing Zang, Casper H.J. van Eijck, Nicole S. Erler, Shanta Mancham, Jaap Kwekkeboom, Patrick P.C. Boor, Dave Sprengers, Xudong Tang, Katharina Biermann, Iris J. Levink, Kostandinos Sideras, Marco J. Bruno
Publikováno v:
British Journal of Cancer, 122(8), 1211-1218. Nature Publishing Group
British Journal of Cancer
British Journal of Cancer
Background HHLA2 is a recently discovered member of the B7-family of immune checkpoint molecules with limited expression in normal tissues but overexpression in several types of cancer. The aim was to determine the expression, prevalence and biologic
Autor:
Aafke A, Duizendstra, Robert J, de Knegt, Shanta, Mancham, Mariska, Klepper, Dave L, Roelen, Simone H, Brand-Schaaf, Patrick P, Boor, Michail, Doukas, Robert A, de Man, Dave, Sprengers, Maikel P, Peppelenbosch, Michiel G H, Betjes, Jaap, Kwekkeboom, Nicolle H R, Litjens
Publikováno v:
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. 28(1)
Spontaneous operational tolerance to the allograft develops in a proportion of liver transplantation (LT) recipients weaned off immunosuppressive (IS) drugs. Several studies have investigated whether peripheral blood circulating T cells could play a
Autor:
Guoying Zhou, Jaap Kwekkeboom, Michail Doukas, Patrick P.C. Boor, Zhouhong Ge, Lucia Campos Carrascosa, Lisanne Noordam, Dave Sprengers, Thierry P P van den Bosch, Jan N. M. IJzermans, Marco J. Bruno, Hadiye Özturk, Qiuwei Pan, Shanta Mancham
Publikováno v:
Cancers
Volume 13
Issue 10
Cancers, Vol 13, Iss 2499, p 2499 (2021)
Cancers, 13(10):2499. Multidisciplinary Digital Publishing Institute (MDPI)
Volume 13
Issue 10
Cancers, Vol 13, Iss 2499, p 2499 (2021)
Cancers, 13(10):2499. Multidisciplinary Digital Publishing Institute (MDPI)
Simple Summary High recurrence rates after resection of liver cancer (hepatocellular carcinoma) with curative intent impair clinical outcomes of patients diagnosed with liver cancer. Cancer/testis antigens (CTAs) are expressed in cancer and can serve
Autor:
Lisanne Noordam, Zhouhong Ge, Hadiye Özturk, Michail Doukas, Shanta Mancham, Patrick P.C. Boor, Lucia Campos Carrascosa, Guoying Zhou, Thierry P.P. van den Bosch, Qiuwei Pan, Jan N.M. IJzermans, Marco J. Bruno, Dave Sprengers, Jaap Kwekkeboom
Background: High recurrence rates after resection of hepatocellular cancer (HCC) with curative intent and lack of effective therapy for advanced disease impair clinical outcomes of HCC. Cancer/testis antigens (CTAs) are suitable targets for cancer im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac9c3faefa39248f218139c8fd26d885
https://doi.org/10.21203/rs.3.rs-45347/v1
https://doi.org/10.21203/rs.3.rs-45347/v1