Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Shanta, Dhar"'
Publikováno v:
Addiction Neuroscience, Vol 4, Iss , Pp 100027- (2022)
Opioid addiction is a worldwide public health crisis stemming from the well-intentioned efforts of physicians to improve pain management in the 1990’s. The lack of knowledge behind the addictive tendencies of opioids, led to what is now known as th
Externí odkaz:
https://doaj.org/article/376c231f660e43fa92890eae485b3205
Autor:
Akil A. Kalathil, Subham Guin, Akash Ashokan, Uttara Basu, Bapurao Surnar, Katiana S. Delma, Leonor M. Lima, Oleksandr N. Kryvenko, Shanta Dhar
Publikováno v:
ACS Central Science, Vol 9, Iss 8, Pp 1705-1705 (2023)
Externí odkaz:
https://doaj.org/article/6a087f0f7bbe4fffaa52137b6202429e
Publikováno v:
Dalton Transactions. 52:3575-3585
We report the synthesis of a curcumin–cisplatin combination chemotherapeutic agent, Platin-C, suitably packaged in a mitochondrion-targeted nanovehicle for enhanced anticancer efficacy and diminished chemotherapy-associated inflammation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65bfa03c68d1171c4ec399378a1ea5fa
https://doi.org/10.1039/d2dt03149c
https://doi.org/10.1039/d2dt03149c
Autor:
Andrew J. Ciciriello, Bapurao Surnar, Giovanni D. Medy, Xiaoyu Su, Shanta Dhar, Courtney M. Dumont
Publikováno v:
Acta Biomaterialia. 152:532-545
Drug delivery requires precision in timing, location, and dosage to achieve therapeutic benefits. Challenges in addressing all three of these critical criteria result in poor temporal dexterity, widespread accumulation and off-target effects, and hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e27a5683237edc4227839156c0631ff4
https://doi.org/10.1016/j.actbio.2022.08.077
https://doi.org/10.1016/j.actbio.2022.08.077
Cancer cells maintain normal mitochondrial glutathione as one of the defense mechanisms to inhibit mitochondrial membrane polarization and hence apoptosis. A combinational therapeutic modality Platin-Cbl, a prodrug of FDA-approved chemotherapeutic ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28a0789b45a9197074ec1d325cfdbe13
https://doi.org/10.1158/1535-7163.c.6538749.v1
https://doi.org/10.1158/1535-7163.c.6538749.v1
Supplementary Materials and Methods. Figure S1. 1H NMR of Platin-Cbl using DMSO-d6; Figure S2. 13C NMR of Platin-Cbl using DMSO-d6; Figure S3. 195Pt NMR of Platin-Cbl using DMSO-d6; Figure S4. HRMS-ESI of Platin-Cbl along with observed and calculated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aafe3ccc3bedca6b9c15dd071fe20d6c
https://doi.org/10.1158/1535-7163.22507647.v1
https://doi.org/10.1158/1535-7163.22507647.v1
Publikováno v:
Acc Mater Res
Since its discovery in 1965, the inorganic drug cisplatin has become a mainstay of cancer therapies and has inspired many platinum (Pt)-based compounds to solve various issues of toxicity and limitations associated with the original cisplatin. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e807b212b3106eb3f84e6ba748f8407
https://doi.org/10.1021/accountsmr.1c00178
https://doi.org/10.1021/accountsmr.1c00178
Autor:
Leonidas G. Bachas, Elnaz Zeynaloo, Dharmendra Shukla, Joshua L. Cohn, Mary O. Olagunju, Shanta Dhar, Bapurao Surnar, Marc R. Knecht, Elsayed M. Zahran
Publikováno v:
Langmuir. 37:11986-11995
The development of photocatalytic materials that exploit visible light is imperative for their sustainable application in environmental remediation. While a variety of approaches have been attempted, facile routes to achieve such structures remain li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0dad7f548fd5db79ea4c95f371c1478
https://doi.org/10.1021/acs.langmuir.1c01537
https://doi.org/10.1021/acs.langmuir.1c01537
Publikováno v:
Biomacromolecules
As the COVID-19 pandemic has continued to spread, studies have shown that hospitalized COVID-19 patients are at significant risk for developing acute kidney injury (AKI), which can cause increased morbidity, the need for dialysis treatment, chronic k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47fd777875d6712e1a0e763468d10cec
https://doi.org/10.1021/acs.biomac.1c00799
https://doi.org/10.1021/acs.biomac.1c00799
Autor:
Nilesh Deshpande, Anna Bianchi, Iago De Castro Silva, Bapu Surnar, Ifeanyichukwu Ogobuiro, Siddharth Mehra, Samara Singh, Vanessa Garrido, Nipun Merchant, Shanta Dhar, Jashodeep Datta
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a8e0f76790928b879460ddaff5b9876
https://doi.org/10.1136/jitc-2022-sitc2022.1224
https://doi.org/10.1136/jitc-2022-sitc2022.1224