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Fenretinide differentially modulates the levels of long- and very long-chain ceramides by downregulating Cers5 enzyme: evidence from bench to bedside

Autor: Daniel Houle, Danuta Radzioch, Juan B. De Sanctis, Shanon Cupri, John W. Hanrahan, Elias Matouk, Dušan Garić, Gabriella Wojewodka, Marian Hajduch, Asmahan Abu-Arish

Publikováno v: Journal of Molecular Medicine. 95:1053-1064

Cystic fibrosis is the most common genetic disease, in which symptoms may be alleviated but not fully eliminated. Ceramides have long been implicated in the inflammatory etiology of cystic fibrosis, with contradicting reports with regards to their ro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeec33d3b0a8f4c1c3cb7fa94115aaf5
https://doi.org/10.1007/s00109-017-1564-y

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