Výsledky vyhledávání - "Shannon Mathewes"

Molecular Cloning, Expression, and Partial Characterization of Two Novel Members of the Ovalbumin Family of Serine Proteinase Inhibitors

Autor: Jeffrey R. Dahlen, Shannon Mathewes, Sara K. Schrader, Cindy A. Sprecher, Walter Kisiel, Kurt A. Morgenstern, Donald C. Foster

Publikováno v: Journal of Biological Chemistry. 270:29854-29861

A human placental lambda gt11 cDNA library was screened for sequences encoding proteins related to human proteinase inhibitor 6 (PI6), and two plaques were identified that displayed weak hybridization at high stringency. Isolation and characterizatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb2f5cdd39a948248dab1db30c7e8cc
https://doi.org/10.1074/jbc.270.50.29854

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Elucidation of the mechanism of CryIIIA overproduction in a mutagenized strain ofBacillus thuringiensisvar.tenebrionis

Autor: Patrick J. O'Hara, Hanne Gurtler, Lee F. Adams, Shannon Mathewes, Petersen Annette S

Publikováno v: Molecular Microbiology. 14:381-389

Summary NB176 is a Bacillus thuringiensis mutant derived by λ-irradiation of NB125 Bacillus thuringiensis var. tenebrionis (Krieg). It exhibits two interesting phenotypes: (i) oligosporogeny and (ii) twofold to threefold overproduction of the CryIII

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ac4c426586cdeaeb88457d72c73893
https://doi.org/10.1111/j.1365-2958.1994.tb01298.x

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Molecular cloning, cDNA sequence, and bacterial expression of human glutamine:fructose-6-phosphate amidotransferase

Autor: Shannon Mathewes, S Marshall, Paul O. Sheppard, Gary L. McKnight, R R Traxinger, Patrick J. O'Hara, S L Mudri

Publikováno v: Journal of Biological Chemistry. 267:25208-25212

Glutamine:fructose-6-phosphate amidotransferase (GFAT) has recently been shown to be an insulin-regulated enzyme that plays a key role in the induction of insulin resistance in cultured cells. As a first step in understanding the molecular regulation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a38e16b245b2b5f480cf9531e2f3e3f0
https://doi.org/10.1016/s0021-9258(19)74026-5

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Molecular cloning of porcine alveolar macrophage-derived neutrophil chemotactic factors I and II: identification of porcine IL-8 and another intercrine-.alpha. protein

Autor: Joseph L. Kuijper, Shannon Mathewes, Richard B. Goodman, John W. Forstrom, Donald C. Foster, Thomas R. Martin, Sherri G. Osborn

Publikováno v: Biochemistry. 31:10483-10490

Alveolar macrophages (AM) mediate lung inflammation by producing lipid and peptide molecules that attract neutrophils (PMN) to the lung. Recently we described two porcine proteins called alveolar macrophage-derived chemotactic factors, AMCF-I and -II

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7474a9cc11712df0544a064d22de5918
https://doi.org/10.1021/bi00158a011

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Sequence of Human Galanin and Its Inhibition of Glucose-Stimulated Insulin Secretion From RIN Cells

Autor: Shannon Mathewes, Gerald J. Taborsky, Stephan Kowalyk, Gary L. McKnight, Allan E. Karlsen, Paul O. Sheppard, Patrick J. O'Hara

Publikováno v: Diabetes. 41:82-87

Human progalanin cDNA was cloned with polymerase chain reaction techniques. The cDNA sequence predicts that the human form of galanin has a substitution of the glycine residue found at position 30 in other species and thus is likely to retain this re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f618586647e156e4bda5aef292a3d29
https://doi.org/10.2337/diab.41.1.82

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Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10

Autor: William Hagopian, Don Foster, David A. Adler, Christine M. Disteche, Catherine E. Grubin, Francis J. Grant, Åke Lernmark, Syamalima Dube, Allan E. Karlsen, Shannon Mathewes, Heike Bärmeier

Publikováno v: Proceedings of the National Academy of Sciences. 88:8337-8341

Glutamic acid decarboxylase (GAD; glutamate decarboxylase, L-glutamate 1-carboxy-lyase, EC 4.1.1.15), which catalyzes formation of gamma-aminobutyric acid from L-glutamic acid, is detectable in different isoforms with distinct electrophoretic and kin

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https://doi.org/10.1073/pnas.88.19.8337

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Molecular cloning, expression, and partial characterization of a second human tissue-factor-pathway inhibitor

Autor: Walter Kisiel, Shannon Mathewes, Donald C. Foster, Cindy A. Sprecher

Previous studies have shown that tissue-factor-pathway inhibitor (TFPI) is an important regulator of the extrinsic pathway of blood coagulation through its ability to inhibit factor Xa and factor VIIa-tissue factor activity. We describe the molecular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af846e4b048553d01f9f73d9b3b01199
https://europepmc.org/articles/PMC43575/

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The human glucagon receptor encoding gene: structure, cDNA sequence and chromosomal localization

Autor: Paul O. Sheppard, Donald C. Foster, Shannon Mathewes, Si Lok, Francis J. Grant, Cindy A. Sprecher, Patrick J. O'Hara, Laura J. Jelinek, Joseph L. Kuijper, Gary B. Rosenberg, Wayne R. Kindsvogel, Janet M. Kramer, Theodore E. Whitmore, Shaula H. Biggs

Publikováno v: Gene. 140(2)

Characterization of the human glucagon-receptor-encoding gene (GGR) should provide a greater understanding of blood glucose regulation and may reveal a genetic basis for the pathogenesis of diabetes. A cDNA encoding a complete functional human glucag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddb7fd6f1d5740574af07e8351fb6402
https://pubmed.ncbi.nlm.nih.gov/8144028

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