Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Shannon Manzi"'
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61468 (2013)
Drug-drug interactions (DDIs) can lead to serious and potentially lethal adverse events. In recent years, several drugs have been withdrawn from the market due to interaction-related adverse events (AEs). Current methods for detecting DDIs rely on th
Externí odkaz:
https://doaj.org/article/cf92d19690964d739ca5b86f50b5e203
Autor:
Timothy M Herr, Suzette J Bielinski, Erwin Bottinger, Ariel Brautbar, Murray Brilliant, Christopher G Chute, Beth L Cobb, Joshua C Denny, Hakon Hakonarson, Andrea L Hartzler, George Hripcsak, Joseph Kannry, Isaac S Kohane, Iftikhar J Kullo, Simon Lin, Shannon Manzi, Keith Marsolo, Casey Lynnette Overby, Jyotishman Pathak, Peggy Peissig, Jill Pulley, James Ralston, Luke Rasmussen, Dan M Roden, Gerard Tromp, Timothy Uphoff, Chunhua Weng, Wendy Wolf, Marc S Williams, Justin Starren
Publikováno v:
Journal of Pathology Informatics, Vol 6, Iss 1, Pp 50-50 (2015)
Background: Genomic medicine has the potential to improve care by tailoring treatments to the individual. There is consensus in the literature that pharmacogenomics (PGx) may be an ideal starting point for real-world implementation, due to the presen
Externí odkaz:
https://doaj.org/article/b8b223e0710f4c67b15f41599205674d
Autor:
Alon Geva, Chen Lin, Kenneth D. Mandl, Paul Avillach, Jason Stedman, Shannon Manzi, Guergana Savova
Publikováno v:
JAMIA Open
ObjectiveTo advance use of real-world data (RWD) for pharmacovigilance, we sought to integrate a high-sensitivity natural language processing (NLP) pipeline for detecting potential adverse drug events (ADEs) with easily interpretable output for high-
Publikováno v:
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 79(9)
Purpose In this descriptive report, we describe a unique trial of pharmacist participation in a multidisciplinary pediatric emergency department disaster simulation exercise. With the number of disasters increasing worldwide, the role of pharmacists
Several drugs repurposed as COVID-19 treatment are in short supply. We collect data from MediaCloud and Google Health Trends about eight drugs proposed for repurposing as COVID-19 treatments and reported to be in shortage by the U.S. Food and Drug Ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cf4dd757b4b2a90a67b6d1684935094
https://doi.org/10.1101/2020.10.12.20211656
https://doi.org/10.1101/2020.10.12.20211656
Publikováno v:
The Lancet Global Health. 10:e330
Patients dispensed medications with actionable pharmacogenomic biomarkers: rates and characteristics
Publikováno v:
Genetics in medicine : official journal of the American College of Medical Genetics. 23(4)
Purpose Pharmacogenomic biomarkers are increasingly listed on medication labels and authoritative guidelines but pharmacogenomic-guided prescribing is not yet common. Our objective was to assess the potential for incorporating knowledge of patients'
Autor:
Shannon Manzi, Dhara D Shah
Publikováno v:
Pediatric Emergency Care. 34:497-500
This study aimed to assess the frequency, type, and potential severity of errors intercepted by pharmacists on review of discharge prescriptions in a pediatric emergency department (ED). This was a retrospective, observational study conducted in the
Publikováno v:
Pediatrics. 141:S434-S438
Oxcarbazepine is an antiepileptic drug (AED) commonly used as a first-line treatment option for focal epilepsy. Several AEDs, including carbamazepine, oxcarbazepine, and phenytoin are associated with various delayed-hypersensitivity reactions such as
Autor:
Weizhen Tan, Shannon Manzi, Asaf Vivante, Thomas M. Kitzler, Michael J. Somers, Eugen Widmeier, Deborah R. Stein, Michelle A. Baum, Hannah Hugo, Shazia Ashraf, Michael A. J. Ferguson, Ankana Daga, Avram Z. Traum, Amelie T. van der Ven, Svjetlana Lovric, Nancy Rodig, Shrikant Mane, Heung Bae Kim, Makiko Nakayama, Jillian K. Warejko, Shirlee Shril, Friedhelm Hildebrandt, Jing Chen, Amar J. Majmundar, Kassaundra Amann, Richard P. Lifton, Leslie Spaneas, Ronen Schneider, Daniela A. Braun, Ghaleb Daouk, Tilman Jobst-Schwan, Nina Mann, Hadas Ityel, Dervla M. Connaughton, Khashayar Vakili
Background Whole-exome sequencing (WES) finds a CKD-related mutation in approximately 20% of patients presenting with CKD before 25 years of age. Although provision of a molecular diagnosis could have important implications for clinical management, e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6e95378a9e50475a10bcc34adc4cf3
https://europepmc.org/articles/PMC6362619/
https://europepmc.org/articles/PMC6362619/