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pro vyhledávání: '"Shannon M. Swikert"'
Autor:
Lukas Tamayo-Orrego, Chia-Lun Wu, Nicolas Bouchard, Ahmed Khedher, Shannon M. Swikert, Marc Remke, Patryk Skowron, Michael D. Taylor, Frédéric Charron
Publikováno v:
Cell Reports, Vol 14, Iss 12, Pp 2925-2937 (2016)
How brain tumors progress from precancerous lesions to advanced cancers is not well understood. Using Ptch1+/− mice to study medulloblastoma progression, we found that Ptch1 loss of heterozygosity (LOH) is an early event that is associated with hig
Externí odkaz:
https://doaj.org/article/5325309091c64d3382be0994b9f66ca2
Publikováno v:
Cell Cycle
The mechanisms leading to brain tumor formation are poorly understood. Using Ptch1+/− mice as a medulloblastoma model, sequential mutations were found to shape tumor evolution. Initially, medulloblastoma preneoplastic lesions display loss of hetero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5dc10099687a4223936d0c2abd20d41
https://doi.org/10.1080/15384101.2016.1189044
https://doi.org/10.1080/15384101.2016.1189044
Autor:
Lukas Tamayo-Orrego, Chia-Lun Wu, Frédéric Charron, Nicolas Bouchard, Patryk Skowron, Michael D. Taylor, Marc Remke, Ahmed Khedher, Shannon M. Swikert
Publikováno v:
Cell Reports, Vol 14, Iss 12, Pp 2925-2937 (2016)
Summary How brain tumors progress from precancerous lesions to advanced cancers is not well understood. Using Ptch1 +/− mice to study medulloblastoma progression, we found that Ptch1 loss of heterozygosity (LOH) is an early event that is associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd7194d126dc1e65ccd00317cad60ec
https://pubmed.ncbi.nlm.nih.gov/26997276
https://pubmed.ncbi.nlm.nih.gov/26997276