Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Shannon M. Gallagher-Colombo"'
Autor:
Amit Maity, Constantinos Koumenis, Nicholas Denko, Sergei A. Vinogradov, Tatiana V. Esipova, Ramon Sun, Alexander Lin, Theresa M. Busch, Stephen Tuttle, Natalie A. Daurio, Shannon M. Gallagher-Colombo, Souvik Dey, George J. Cerniglia
Supplementary Figures 1-9; Supplementary Table 1. Suppl. Fig. 1 Western blotting for downstream targets of PI3K and mTOR. Suppl. Fig. 2 Effect of dual PI3K/mTOR inhibitors on OCR. Suppl. Fig. 3 Effect of BEZ235 on mitochondrial mass and membrane pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f4179956747d01dfc147a099355562
https://doi.org/10.1158/1535-7163.22501992
https://doi.org/10.1158/1535-7163.22501992
Autor:
Theresa M. Busch, Sergei A. Vinogradov, Mary E. Putt, Keith A. Cengel, Joann Miller, Shannon M. Gallagher-Colombo
Supplemental Figures 1-7. Supplemental Figure 1. Erlotinib does not alter oxygenation of tumors Supplemental Figure 2. Erlotinib increases in vivo tumor cell death at delayed timepoints. Supplemental Figure 3. In vivo imaging of tumor perfusion is we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271d9c59c5ac1eb0d5d84f7f9083a21a
https://doi.org/10.1158/0008-5472.22405017.v1
https://doi.org/10.1158/0008-5472.22405017.v1
Autor:
Theresa M. Busch, Sergei A. Vinogradov, Mary E. Putt, Keith A. Cengel, Joann Miller, Shannon M. Gallagher-Colombo
Supplemental Materials and Methods. This file contains supplemental materials and methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685c99b2f9ec69bde1afd06b5328e235
https://doi.org/10.1158/0008-5472.22405014
https://doi.org/10.1158/0008-5472.22405014
Autor:
Ara A. Chalian, Bert W. O'Malley, Peter H. Ahn, Theresa M. Busch, Virginia A. LiVolsi, Gregory S. Weinstein, Timothy C. Zhu, Keith A. Cengel, Jarod C. Finlay, Shannon M. Gallagher-Colombo, Kelly M. Malloy, Harry Quon, Michael Feldman, Alexander Lin, Charles B. Simone, Martin S. Greenberg, Rosemarie Mick, Sally McNulty, Thomas P. Sollecito
Publikováno v:
Photodiagnosis and Photodynamic Therapy. 21:28-35
Background We report on a Phase 1 trial of photodynamic therapy (PDT) for superficial head and neck (H&N) lesions. Due to known oxygen dependencies of PDT, translational measurements of lesion hemoglobin oxygen saturation (StO2) and blood volume (tHb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f8b44c075a0c41231021eefaa580ac4
https://doi.org/10.1016/j.pdpdt.2017.10.015
https://doi.org/10.1016/j.pdpdt.2017.10.015
Autor:
Theresa M. Busch, Joann Miller, Mary E. Putt, Keith A. Cengel, Sergei A. Vinogradov, Shannon M. Gallagher-Colombo
Publikováno v:
Cancer Research. 75:3118-3126
Aberrant expression of the epidermal growth factor receptor (EGFR) is a common characteristic of many cancers, including non–small cell lung carcinoma (NSCLC), head and neck squamous cell carcinoma, and ovarian cancer. Although EGFR is currently a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8511a5eca475559fd2e99d6f0abc2fee
https://doi.org/10.1158/0008-5472.can-14-3304
https://doi.org/10.1158/0008-5472.can-14-3304
Autor:
Shannon M. Gallagher-Colombo, Sarah Hagan, Theresa M. Busch, Christine E Edmonds, Keith A. Cengel
Publikováno v:
Cancer Biology & Therapy. 13:1463-1470
Patients with serosal (pleural or peritoneal) spread of malignancy have few definitive treatment options and consequently have a very poor prognosis. We have previously shown that photodynamic therapy (PDT) can be an effective treatment for these pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a304578584f4021bf3e238eddcb8650
https://doi.org/10.4161/cbt.22256
https://doi.org/10.4161/cbt.22256
Publikováno v:
Israel Journal of Chemistry. 52:681-690
Photodynamic therapy (PDT) can be a highly effective treatment for diseases ranging from actinic keratosis to cancer. While use of this therapy shows great promise in preclinical and clinical studies, understanding the molecular consequences of PDT i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f653ec3988038159ac422eef5632e61
https://doi.org/10.1002/ijch.201200011
https://doi.org/10.1002/ijch.201200011
Autor:
Jarod C. Finlay, Peter H. Ahn, Kelly M. Malloy, Ara A. Chalian, Harry Quon, Charles B. Simone, Bert W. O'Malley, Gregory S. Weinstein, Mary E. Putt, Timothy C. Zhu, Keith A. Cengel, Shannon M. Gallagher-Colombo, Theresa M. Busch
Photodynamic therapy (PDT) can treat superficial, early-stage disease with minimal damage to underlying tissues and without cumulative dose-limiting toxicity. Treatment efficacy is affected by disease physiologic properties, but these properties are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e837dfb84a3096beb5bae5b3f15c456
https://europepmc.org/articles/PMC4560604/
https://europepmc.org/articles/PMC4560604/
Publikováno v:
Resistance to Targeted Anti-Cancer Therapeutics ISBN: 9783319127293
The tumor microenvironment is a complex force to be reckoned with in terms of cancer treatment. Structure and composition of the tumor stroma, oxygenation status within the tumor, and expression and/or activation of proteins that mediate tumor progre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c557e258f9999cdd6e8ffc5d584b14cb
https://doi.org/10.1007/978-3-319-12730-9_3
https://doi.org/10.1007/978-3-319-12730-9_3
Autor:
George J. Cerniglia, Sergei A. Vinogradov, Alexander Lin, Souvik Dey, Stephen W. Tuttle, Constantinos Koumenis, Natalie A. Daurio, Theresa M. Busch, Shannon M. Gallagher-Colombo, Ramon C. Sun, Amit Maity, Nicholas C. Denko, Tatiana V. Esipova
Publikováno v:
Molecular cancer therapeutics. 14(8)
Inhibition of the PI3K/Akt pathway decreases hypoxia within SQ20B human head and neck cancer xenografts. We set out to understand the molecular mechanism underlying this observation. We measured oxygen consumption using both a Clark electrode and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c0d15f4de88e73898c293605d938f05
https://pubmed.ncbi.nlm.nih.gov/25995437
https://pubmed.ncbi.nlm.nih.gov/25995437