Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Shannon M. Gallagher"'
Autor:
Amit Maity, Constantinos Koumenis, Nicholas Denko, Sergei A. Vinogradov, Tatiana V. Esipova, Ramon Sun, Alexander Lin, Theresa M. Busch, Stephen Tuttle, Natalie A. Daurio, Shannon M. Gallagher-Colombo, Souvik Dey, George J. Cerniglia
Supplementary Figures 1-9; Supplementary Table 1. Suppl. Fig. 1 Western blotting for downstream targets of PI3K and mTOR. Suppl. Fig. 2 Effect of dual PI3K/mTOR inhibitors on OCR. Suppl. Fig. 3 Effect of BEZ235 on mitochondrial mass and membrane pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71f4179956747d01dfc147a099355562
https://doi.org/10.1158/1535-7163.22501992
https://doi.org/10.1158/1535-7163.22501992
Supplementary Figure 1 from Monocarboxylate Transporter 4 Regulates Maturation and Trafficking of CD147 to the Plasma Membrane in the Metastatic Breast Cancer Cell Line MDA-MB-231
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32dce6b2ba6102bef94e7dfc131ed854
https://doi.org/10.1158/0008-5472.22368140.v1
https://doi.org/10.1158/0008-5472.22368140.v1
Metastatic cancer cells increase glucose consumption and metabolism via glycolysis, producing large quantities of lactate. Recent work has shown that lactate efflux is mediated by monocarboxylate transporters (MCT), which are composed of a catalytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04616675e3d08ed9d1a1dabad4ef9d8d
https://doi.org/10.1158/0008-5472.c.6495830.v1
https://doi.org/10.1158/0008-5472.c.6495830.v1
Autor:
Theresa M. Busch, Sergei A. Vinogradov, Mary E. Putt, Keith A. Cengel, Joann Miller, Shannon M. Gallagher-Colombo
Supplemental Figures 1-7. Supplemental Figure 1. Erlotinib does not alter oxygenation of tumors Supplemental Figure 2. Erlotinib increases in vivo tumor cell death at delayed timepoints. Supplemental Figure 3. In vivo imaging of tumor perfusion is we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271d9c59c5ac1eb0d5d84f7f9083a21a
https://doi.org/10.1158/0008-5472.22405017.v1
https://doi.org/10.1158/0008-5472.22405017.v1
Autor:
Theresa M. Busch, Sergei A. Vinogradov, Mary E. Putt, Keith A. Cengel, Joann Miller, Shannon M. Gallagher-Colombo
Supplemental Materials and Methods. This file contains supplemental materials and methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685c99b2f9ec69bde1afd06b5328e235
https://doi.org/10.1158/0008-5472.22405014
https://doi.org/10.1158/0008-5472.22405014
Autor:
Judy Garber, Eric Rosenthal, Shannon M. Gallagher, Elisha Hughes, Susan M. Domchek, Braden Probst, Jeffrey N. Weitzel, Thomas P. Slavin, Placede Tshiaba, Mark E. Robson, Alexander Gutin, Allison W. Kurian, Benjamin B. Roa, Brian Morris, Susanne Wagner, Jerry S. Lanchbury
Publikováno v:
Cancer Research. 81:PD10-09
Background: Germline pathogenic variants (PVs) in the moderate penetrance ATM gene confer a roughly 2-fold increased risk for breast cancer. Currently, any woman with an ATM PV meets the >20% lifetime risk threshold for consideration of relatively ag
Autor:
Ara A. Chalian, Bert W. O'Malley, Peter H. Ahn, Theresa M. Busch, Virginia A. LiVolsi, Gregory S. Weinstein, Timothy C. Zhu, Keith A. Cengel, Jarod C. Finlay, Shannon M. Gallagher-Colombo, Kelly M. Malloy, Harry Quon, Michael Feldman, Alexander Lin, Charles B. Simone, Martin S. Greenberg, Rosemarie Mick, Sally McNulty, Thomas P. Sollecito
Publikováno v:
Photodiagnosis and Photodynamic Therapy. 21:28-35
Background We report on a Phase 1 trial of photodynamic therapy (PDT) for superficial head and neck (H&N) lesions. Due to known oxygen dependencies of PDT, translational measurements of lesion hemoglobin oxygen saturation (StO2) and blood volume (tHb
Autor:
Sheeri Hanjra, Jerod Parsons, Jun Hu, Joshua Drews, Jack Michuda, Calvin McCarter, Naihui Zhou, Nike Beaubier, Josh Sk Bell, Jenna Malinauskas, Shannon M. Gallagher, Nithya Sreenivasan, Jack C. Tyndall, Brittany Mineo, Rasika Dhond, Robert Tell, Richard A. Blidner, Ankit Jambusaria, Catherine Igartua
Publikováno v:
Cancer Research. 81:2239-2239
Tumor genome sequencing has emerged as a powerful tool for identifying biomarkers for targeted cancer therapies. While DNA sequencing is a well-established method and considered a gold standard, RNA sequencing (RNA-seq) can identify anomalies in gene
Autor:
Theresa M. Busch, Joann Miller, Mary E. Putt, Keith A. Cengel, Sergei A. Vinogradov, Shannon M. Gallagher-Colombo
Publikováno v:
Cancer Research. 75:3118-3126
Aberrant expression of the epidermal growth factor receptor (EGFR) is a common characteristic of many cancers, including non–small cell lung carcinoma (NSCLC), head and neck squamous cell carcinoma, and ovarian cancer. Although EGFR is currently a
Autor:
Shannon M. Gallagher-Colombo, Sarah Hagan, Theresa M. Busch, Christine E Edmonds, Keith A. Cengel
Publikováno v:
Cancer Biology & Therapy. 13:1463-1470
Patients with serosal (pleural or peritoneal) spread of malignancy have few definitive treatment options and consequently have a very poor prognosis. We have previously shown that photodynamic therapy (PDT) can be an effective treatment for these pat