Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Shannon M. Beaty"'
Autor:
Satoshi Ikegame, Shannon M Beaty, Christian Stevens, Taylor Won, Arnold Park, David Sachs, Patrick Hong, Benhur Lee, Patricia A Thibault
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008877 (2020)
The antigenic and genomic stability of paramyxoviruses remains a mystery. Here, we evaluate the genetic plasticity of Sendai virus (SeV) and mumps virus (MuV), sialic acid-using paramyxoviruses that infect mammals from two Paramyxoviridae subfamilies
Externí odkaz:
https://doaj.org/article/c4fa34d2d8c24fb08f8972c939d22f10
Autor:
Benjamin O. Fulton, David Sachs, Shannon M. Beaty, Sohui T. Won, Benhur Lee, Peter Palese, Nicholas S. Heaton
Publikováno v:
Cell Reports, Vol 11, Iss 9, Pp 1331-1338 (2015)
Measles virus undergoes error-prone replication like other RNA viruses, but over time, it has remained antigenically monotypic. The constraints on the virus that prevent the emergence of antigenic variants are unclear. As a first step in understandin
Externí odkaz:
https://doaj.org/article/572093e3f28746d19e5c05d542a4dbdd
Autor:
Shannon M. Beaty, Arnold Park, Sohui T. Won, Patrick Hong, Michael Lyons, Frederic Vigant, Alexander N. Freiberg, Benjamin R. tenOever, W. Paul Duprex, Benhur Lee
Publikováno v:
mSphere, Vol 2, Iss 2 (2017)
ABSTRACT The notoriously low efficiency of Paramyxoviridae reverse genetics systems has posed a limiting barrier to the study of viruses in this family. Previous approaches to reverse genetics have utilized a wide variety of techniques to overcome th
Externí odkaz:
https://doaj.org/article/9ed5da7edaf44f2b8d23894e3de833c7
Autor:
Mickey Pentecost, Ajay A Vashisht, Talia Lester, Tim Voros, Shannon M Beaty, Arnold Park, Yao E Wang, Tatyana E Yun, Alexander N Freiberg, James A Wohlschlegel, Benhur Lee
Publikováno v:
PLoS Pathogens, Vol 11, Iss 3, p e1004739 (2015)
The paramyxovirus matrix (M) protein is a molecular scaffold required for viral morphogenesis and budding at the plasma membrane. Transient nuclear residence of some M proteins hints at non-structural roles. However, little is known regarding the mec
Externí odkaz:
https://doaj.org/article/e0e16e96e7c14b2eb3f3d427fa4a45e5
Autor:
Shannon M. Beaty, Benhur Lee
Publikováno v:
Viruses, Vol 8, Iss 4, p 109 (2016)
Antigenic drift and genetic variation are significantly constrained in measles virus (MeV). Genetic stability of MeV is exceptionally high, both in the lab and in the field, and few regions of the genome allow for rapid genetic change. The regions of
Externí odkaz:
https://doaj.org/article/e7dd1a1f2131450ca568bcfc4907d169
Autor:
Terence E. Hill, Shannon M. Beaty, Tatyana Yun, Yao E. Wang, Benhur Lee, Frederic Vigant, Junling Gao, Lihong Zhang, Arnold Park, Terry L. Juelich, Alexander N. Freiberg, Olivier Pernet, Ping Wu, Jennifer K. Smith
Publikováno v:
Journal of Virology. 89:1242-1253
Nipah virus (NiV) and Hendra virus (HeV) are closely related henipaviruses of the Paramyxovirinae . Spillover from their fruit bat reservoirs can cause severe disease in humans and livestock. Despite their high sequence similarity, NiV and HeV exhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc3a0d1edc5e23d062f17ab0a38a2409
https://doi.org/10.1128/jvi.02583-14
https://doi.org/10.1128/jvi.02583-14
Publikováno v:
Journal of Virology. 88:5171-5176
Recent evidence identified multiple Henipavirus species in Africa distinct from those in Southeast Asia and Australia. The reported fusion glycoprotein (F) sequence of the African Gh-M74a strain (GhV-F) is likely incorrect: a single base pair deletio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de75db6c0f494a5efd0e722f2ac24026
https://doi.org/10.1128/jvi.03655-13
https://doi.org/10.1128/jvi.03655-13
Autor:
Tara TeSlaa, Michael A. Teitell, Jeff F. Miller, Shannon M. Beaty, Pei-Yu Chiou, Isabelle Toesca, Ting-Hsiang Wu, Imke Schröder, Christopher T. French, Minghsun Liu, Wayne Wong
Publikováno v:
Proceedings of the National Academy of Sciences. 108:12095-12100
Burkholderia pseudomallei and Burkholderia thailandensis are related pathogens that invade a variety of cell types, replicate in the cytoplasm, and spread to nearby cells. We have investigated temporal and spatial requirements for virulence determina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81926704335c76aaba450652e11cbae
https://doi.org/10.1073/pnas.1107183108
https://doi.org/10.1073/pnas.1107183108
Publikováno v:
Proceedings of the National Academy of Sciences. 112
The discovery of African henipaviruses (HNVs) related to pathogenic Hendra virus (HeV) and Nipah virus (NiV) from Southeast Asia and Australia presents an open-ended health risk. Cell receptor use by emerging African HNVs at the stage of host-cell en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed60b90b7d45d6e6fbb218c276b00892
https://doi.org/10.1073/pnas.1501690112
https://doi.org/10.1073/pnas.1501690112
Autor:
Peter Daszak, Christina M. Ramirez, Alexander N. Freiberg, Matthew LeBreton, Bradley S. Schneider, Jonna A. K. Mazet, Tatyana Yun, Nathan D. Wolfe, Arnold Park, Peta L. Hitchens, Olivier Pernet, Thomas A. Bowden, Benhur Lee, Shannon M. Beaty, Trevor T. Zachariah
Publikováno v:
Nature communications, vol 5, iss 1
Nature Communications
Nature Communications
Zoonotic transmission of lethal henipaviruses (HNVs) from their natural fruit bat reservoirs to humans has only been reported in Australia and South/Southeast Asia. However, a recent study discovered numerous HNV clades in African bat samples. To det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7dd129d193307e054af53f448b6f977
https://doi.org/10.1038/ncomms6342
https://doi.org/10.1038/ncomms6342